Synthesis and Pharmacophore Modelling of 2,6,9-Trisubstituted Purine Derivatives and Their Potential Role as Apoptosis-Inducing Agents in Cancer Cell Lines

by Jeannette Calderón-Arancibia, Christian Espinosa-Bustos, Álvaro Cañete-Molina, Ricardo A. Tapia, Mario Faúndez, Maria Jose Torres, Adam Aguirre, Margot Paulino, Cristian O. Salas
Published 2015-04-01

Design, synthesis, cytotoxicity and 3D-QSAR analysis of new 3,6-disubstituted-1,2,4,5-tetrazine derivatives as potential antitumor agents

by Álvaro Cañete-Molina, Christian Espinosa-Bustos, Marcos González-Castro, Mario Faúndez, Jaime Mella, Ricardo A. Tapia, Alan R. Cabrera, Iván Brito, Adam Aguirre, Cristian O. Salas
Published 2019-11-01

Quantification of carbonate radical formation by the bicarbonate-dependent peroxidase activity of superoxide dismutase 1 using pyrogallol red bleaching

by Juan David Figueroa, Eduardo Fuentes-Lemus, Eva Dorta, Victoria Melin, Javiera Cortés-Ríos, Mario Faúndez, David Contreras, Ana Denicola, Beatriz Álvarez, Michael J. Davies, Camilo López-Alarcón
Published 2019-06-01

Protective role of acetylsalicylic acid in experimental Trypanosoma cruzi infection: evidence of a 15-epi-lipoxin A₄-mediated effect.

by Alfredo Molina-Berríos, Carolina Campos-Estrada, Natalia Henriquez, Mario Faúndez, Gloria Torres, Christian Castillo, Sebastián Escanilla, Ulrike Kemmerling, Antonio Morello, Rodrigo A López-Muñoz, Juan D Maya
Published 2013-01-01

Promising 2,6,9-Trisubstituted Purine Derivatives for Anticancer Compounds: Synthesis, 3D-QSAR, and Preliminary Biological Assays

by Cristian O. Salas, Ana Maria Zarate, Vladimir Kryštof, Jaime Mella, Mario Faundez, Jose Brea, María Isabel Loza, Ivan Brito, Denisa Hendrychová, Radek Jorda, Alan R. Cabrera, Ricardo A. Tapia, Christian Espinosa-Bustos
Published 2019-12-01

A New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections

by Javier Campanini-Salinas, Juan Andrades-Lagos, Gerardo Gonzalez Rocha, Duane Choquesillo-Lazarte, Soledad Bollo Dragnic, Mario Faúndez, Pedro Alarcón, Francisco Silva, Roberto Vidal, Edison Salas-Huenuleo, Marcelo Kogan, Jaime Mella, Gonzalo Recabarren Gajardo, David Vásquez-Velásquez
Published 2018-07-01