The Extent of Ventilator-Induced Lung Injury in Mice Partly Depends on Duration of Mechanical Ventilation

by Maria A. Hegeman, Sabrine N. T. Hemmes, Maria T. Kuipers, Lieuwe D. J. Bos, Geartsje Jongsma, Joris J. T. H. Roelofs, Koenraad F. van der Sluijs, Nicole P. Juffermans, Margreeth B. Vroom, Marcus J. Schultz
Published 2013-01-01

Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury.

by Maria T Kuipers, Hamid Aslami, Alexander P J Vlaar, Nicole P Juffermans, Anita M Tuip-de Boer, Maria A Hegeman, Geartsje Jongsma, Joris J T H Roelofs, Tom van der Poll, Marcus J Schultz, Catharina W Wieland
Published 2012-01-01

High levels of S100A8/A9 proteins aggravate ventilator-induced lung injury via TLR4 signaling.

by Maria T Kuipers, Thomas Vogl, Hamid Aslami, Geartsje Jongsma, Elske van den Berg, Alexander P J Vlaar, Joris J T H Roelofs, Nicole P Juffermans, Marcus J Schultz, Tom van der Poll, Johannes Roth, Catharina W Wieland
Published 2013-01-01

Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status.

by Hamid Aslami, Wilco P Pulskens, Maria T Kuipers, Aafkeline P Bos, André B P van Kuilenburg, Ronald J A Wanders, Jeroen Roelofsen, Joris J T H Roelofs, Raphaela P Kerindongo, Charlotte J P Beurskens, Marcus J Schultz, Wim Kulik, Nina C Weber, Nicole P Juffermans
Published 2013-01-01