Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells.

by Grant A Challen, Margaret A Goodell
Published 2008-06-01

LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner.

by Georgi L Lukov, Margaret A Goodell
Published 2010-09-01

DNA methylation and de-methylation using hybrid site-targeting proteins

by Yong Lei, Yung-Hsin Huang, Margaret A. Goodell
Published 2018-11-01

Chk1 haploinsufficiency results in anemia and defective erythropoiesis.

by Nathan C Boles, Sirisha Peddibhotla, Alice J Chen, Margaret A Goodell, Jeffrey M Rosen
Published 2010-01-01

Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation.

by Stuart M Chambers, Chad A Shaw, Catherine Gatza, C Joseph Fisk, Lawrence A Donehower, Margaret A Goodell
Published 2007-08-01

CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway.

by Kuanyin K Lin, Lara Rossi, Nathan C Boles, Brian E Hall, Thaddeus C George, Margaret A Goodell
Published 2011-09-01

Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans.

by Katherine Y King, Justin D Lew, Ngan P Ha, Jeffery S Lin, Xin Ma, Edward A Graviss, Margaret A Goodell
Published 2011-01-01

Molecular signatures of proliferation and quiescence in hematopoietic stem cells.

by Teresa A Venezia, Akil A Merchant, Carlos A Ramos, Nathan L Whitehouse, Andrew S Young, Chad A Shaw, Margaret A Goodell
Published 2004-10-01

Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein

by Yong Lei, Xiaotian Zhang, Jianzhong Su, Mira Jeong, Michael C. Gundry, Yung-Hsin Huang, Yubin Zhou, Wei Li, Margaret A. Goodell
Published 2017-07-01

Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery.

by Juliette J Kahle, George P Souroullas, Peng Yu, Fabian Zohren, Yoontae Lee, Chad A Shaw, Huda Y Zoghbi, Margaret A Goodell
Published 2013-03-01

DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A

by Yung-Hsin Huang, Jianzhong Su, Yong Lei, Lorenzo Brunetti, Michael C. Gundry, Xiaotian Zhang, Mira Jeong, Wei Li, Margaret A. Goodell
Published 2017-09-01

Correction: Evidence for Diversity in Transcriptional Profiles of Single Hematopoietic Stem Cells

by Carlos A Ramos, Teresa A Bowman, Nathan C Boles, Akil A Merchant, Yayun Zheng, Irma Parra, Suzanne A. W Fuqua, Chad A Shaw, Margaret A Goodell
Published 2006-11-01

Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells.

by Jonathan S Berg, Kuanyin K Lin, Corinne Sonnet, Nathan C Boles, David C Weksberg, Hoang Nguyen, Lowenna J Holt, Danny Rickwood, Roger J Daly, Margaret A Goodell
Published 2011-01-01

Homeobox oncogene activation by pan-cancer DNA hypermethylation

by Jianzhong Su, Yung-Hsin Huang, Xiaodong Cui, Xinyu Wang, Xiaotian Zhang, Yong Lei, Jianfeng Xu, Xueqiu Lin, Kaifu Chen, Jie Lv, Margaret A. Goodell, Wei Li
Published 2018-08-01

Evidence for diversity in transcriptional profiles of single hematopoietic stem cells.

by Carlos A Ramos, Teresa A Bowman, Nathan C Boles, Akil A Merchant, Yayun Zheng, Irma Parra, Suzanne A W Fuqua, Chad A Shaw, Margaret A Goodell
Published 2006-09-01

Correction: Evidence for Diversity in Transcriptional Profiles of Single Hematopoietic Stem Cells.

by Carlos A Ramos, Teresa A Bowman, Nathan C Boles, Akil A Merchant, Yayun Zheng, Irma Parra, Suzanne A. W Fuqua, Chad A Shaw, Margaret A Goodell
Published 2006-11-01

Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9

by Michael C. Gundry, Lorenzo Brunetti, Angelique Lin, Allison E. Mayle, Ayumi Kitano, Dimitrios Wagner, Joanne I. Hsu, Kevin A. Hoegenauer, Cliona M. Rooney, Margaret A. Goodell, Daisuke Nakada
Published 2016-10-01

Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons

by Chongyuan Luo, Qian Yi Lee, Orly Wapinski, Rosa Castanon, Joseph R Nery, Moritz Mall, Michael S Kareta, Sean M Cullen, Margaret A Goodell, Howard Y Chang, Marius Wernig, Joseph R Ecker
Published 2019-01-01

A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells

by Lei Guo, Jia Li, Hongxiang Zeng, Anna G. Guzman, Tingting Li, Minjung Lee, Yubin Zhou, Margaret A. Goodell, Clifford Stephan, Peter J. A. Davies, Mark A Dawson, Deqiang Sun, Yun Huang
Published 2020-02-01

Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo

by Mira Jeong, Hyun Jung Park, Hamza Celik, Elizabeth L. Ostrander, Jaime M. Reyes, Anna Guzman, Benjamin Rodriguez, Yong Lei, Yeojin Lee, Lei Ding, Olga A. Guryanova, Wei Li, Margaret A. Goodell, Grant A. Challen
Published 2018-04-01