Monocyte TREM-1 Levels Associate With Anti-TNF Responsiveness in IBD Through Autophagy and Fcγ-Receptor Signaling Pathways

by Marileen M. Prins, Bram Verstockt, Bram Verstockt, Marc Ferrante, Marc Ferrante, Séverine Vermeire, Séverine Vermeire, Manon E. Wildenberg, Manon E. Wildenberg, Pim J. Koelink
Published 2021-03-01

Thiopurines correct the effects of autophagy impairment on intestinal healing – a potential role for ARHGAP18/RhoA

by Marileen M. C. Prins, Francesca P. Giugliano, Manon van Roest, Stan F. J. van de Graaf, Pim J. Koelink, Manon E. Wildenberg
Published 2021-04-01

Colonic CD90+ Crypt Fibroblasts Secrete Semaphorins to Support Epithelial Growth

by Olga N. Karpus, B. Florien Westendorp, Jacqueline L.M. Vermeulen, Sander Meisner, Jan Koster, Vanesa Muncan, Manon E. Wildenberg, Gijs R. van den Brink
Published 2019-03-01

Beneficial Effect of Mildly Pasteurized Whey Protein on Intestinal Integrity and Innate Defense in Preterm and Near-Term Piglets

by Marit Navis, Vanesa Muncan, Per Torp Sangild, Line Møller Willumsen, Pim J. Koelink, Manon E. Wildenberg, Evan Abrahamse, Thomas Thymann, Ruurd M. van Elburg, Ingrid B. Renes
Published 2020-04-01

A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines.

by Aziza A A Adam, Vincent A van der Mark, Joanne M Donkers, Manon E Wildenberg, Ronald P J Oude Elferink, Robert A F M Chamuleau, Ruurdtje Hoekstra
Published 2018-01-01

Characterization of gut-homing molecules in non-endstage livers of patients with primary sclerosing cholangitis and inflammatory bowel disease

by Manon de Krijger, Thijmen Visseren, Manon E. Wildenberg, Gerrit K.J. Hooijer, Monique M.A. Verstegen, Luc J.W. van der Laan, Wouter J. de Jonge, Joanne Verheij, Cyriel Y. Ponsioen
Published 2020-01-01

A Novel Organoid Model of Damage and Repair Identifies HNF4α as a Critical Regulator of Intestinal Epithelial RegenerationSummary

by Paula S. Montenegro-Miranda, Jonathan H.M. van der Meer, Christine Jones, Sander Meisner, Jacqueline L.M. Vermeulen, Jan Koster, Manon E. Wildenberg, Jarom Heijmans, Francois Boudreau, Agnes Ribeiro, Gijs R. van den Brink, Vanesa Muncan
Published 2020-01-01

Intestinal fibrosis is associated with lack of response to Infliximab therapy in Crohn's disease.

by Jessica R de Bruyn, Marte A Becker, Jessica Steenkamer, Manon E Wildenberg, Sybren L Meijer, Christianne J Buskens, Willem A Bemelman, Mark Löwenberg, Cyriel Y Ponsioen, Gijs R van den Brink, Geert R D'Haens
Published 2018-01-01

Early Life Antibiotics Influence In Vivo and In Vitro Mouse Intestinal Epithelium Maturation and FunctioningSummary

by Tânia Martins Garcia, Manon van Roest, Jacqueline L.M. Vermeulen, Sander Meisner, Wouter L. Smit, Joana Silva, Pim J. Koelink, Jan Koster, William J. Faller, Manon E. Wildenberg, Ruurd M. van Elburg, Vanesa Muncan, Ingrid B. Renes
Published 2021-01-01

A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients.

by Andrew Y F Li Yim, Jessica R de Bruyn, Nicolette W Duijvis, Catriona Sharp, Enrico Ferrero, Wouter J de Jonge, Manon E Wildenberg, Marcel M A M Mannens, Christianne J Buskens, Geert R D'Haens, Peter Henneman, Anje A Te Velde
Published 2018-01-01

ATF2 and ATF7 Are Critical Mediators of Intestinal Epithelial RepairSummary

by Bartolomeus J. Meijer, Francesca P. Giugliano, Bart Baan, Jonathan H.M. van der Meer, Sander Meisner, Manon van Roest, Pim J. Koelink, Ruben J. de Boer, Nic Jones, Wolfgang Breitwieser, Nicole N. van der Wel, Manon E. Wildenberg, Gijs R. van den Brink, Jarom Heijmans, Vanesa Muncan
Published 2020-01-01

Indian Hedgehog Suppresses a Stromal Cell–Driven Intestinal Immune Response

by B. Florien Westendorp, Nikè V.J.A. Büller, Olga N. Karpus, Willemijn A. van Dop, Jan Koster, Rogier Versteeg, Pim J. Koelink, Clinton Y. Snel, Sander Meisner, Joris J.T.H. Roelofs, Anja Uhmann, Emiel Ver Loren van Themaat, Jarom Heijmans, Heidi Hahn, Vanesa Muncan, Manon E. Wildenberg, Gijs R. van den Brink
Published 2018-01-01

FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming

by Ivo S. Hansen, Lisette Krabbendam, Jochem H. Bernink, Fabricio Loayza-Puch, Willianne Hoepel, Johan A. van Burgsteden, Elsa C. Kuijper, Christianne J. Buskens, Willem A. Bemelman, Sebastiaan A. J. Zaat, Reuven Agami, Gestur Vidarsson, Gijs R. van den Brink, Esther C. de Jong, Manon E. Wildenberg, Dominique L. P. Baeten, Bart Everts, Jeroen den Dunnen
Published 2018-02-01