Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS

by Clara Tejido, Donya Pakravan, Donya Pakravan, Ludo Van Den Bosch, Ludo Van Den Bosch
Published 2021-08-01

Therapeutic potential of HDAC6 in amyotrophic lateral sclerosis

by Wenting Guo, Ludo Van Den Bosch
Published 2017-12-01

Phasing in on the cell cycle

by Steven Boeynaems, Peter Tompa, Ludo Van Den Bosch
Published 2018-01-01

Current Advances and Limitations in Modeling ALS/FTD in a Dish Using Induced Pluripotent Stem Cells

by Wenting Guo, Wenting Guo, Laura Fumagalli, Laura Fumagalli, Robert Prior, Robert Prior, Ludo Van Den Bosch, Ludo Van Den Bosch
Published 2017-12-01

Modelling amyotrophic lateral sclerosis: progress and possibilities

by Philip Van Damme, Wim Robberecht, Ludo Van Den Bosch
Published 2017-05-01

Defective axonal transport: A common pathological mechanism in inherited and acquired peripheral neuropathies

by Robert Prior, Lawrence Van Helleputte, Veronick Benoy, Ludo Van Den Bosch
Published 2017-09-01

Ivermectin inhibits AMPA receptor-mediated excitotoxicity in cultured motor neurons and extends the life span of a transgenic mouse model of amyotrophic lateral sclerosis

by Maria Andries, Philip Van Damme, Wim Robberecht, Ludo Van Den Bosch
Published 2007-01-01

Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1G93A-induced motor neuron death

by Maarten Dewil, Vidal F. dela Cruz, Ludo Van Den Bosch, Wim Robberecht
Published 2007-05-01

Skeletal muscle properties in a transgenic mouse model for amyotrophic lateral sclerosis: effects of creatine treatment

by Wim Derave, Ludo Van Den Bosch, Griet Lemmens, Bert O Eijnde, Wim Robberecht, Peter Hespel
Published 2003-08-01

Effects of vascular endothelial growth factor (VEGF) on motor neuron degeneration

by Ludo Van Den Bosch, Erik Storkebaum, Vicky Vleminckx, Lieve Moons, Ludo Vanopdenbosch, Wendy Scheveneels, Peter Carmeliet, Wim Robberecht
Published 2004-10-01

Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy.

by Angela S Laird, Annelies Van Hoecke, Louis De Muynck, Mieke Timmers, Ludo Van den Bosch, Philip Van Damme, Wim Robberecht
Published 2010-01-01

RT2 PCR array screening reveals distinct perturbations in DNA damage response signaling in FUS-associated motor neuron disease

by Haibo Wang, Suganya Rangaswamy, Manohar Kodavati, Joy Mitra, Wenting Guo, Erika N. Guerrero, Ludo Van Den Bosch, Muralidhar L. Hegde
Published 2019-12-01

Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice

by Sander Beel, Sarah Herdewyn, Raheem Fazal, Mathias De Decker, Matthieu Moisse, Wim Robberecht, Ludo Van Den Bosch, Philip Van Damme
Published 2018-10-01

Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model

by Elisabeth Rossaert, Eveliina Pollari, Tom Jaspers, Lawrence Van Helleputte, Matthew Jarpe, Philip Van Damme, Katrien De Bock, Matthieu Moisse, Ludo Van Den Bosch
Published 2019-07-01

In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis

by Tiziana Bonifacino, Francesca Provenzano, Elena Gallia, Silvia Ravera, Carola Torazza, Simone Bossi, Sara Ferrando, Aldamaria Puliti, Ludo Van Den Bosch, Giambattista Bonanno, Marco Milanese
Published 2019-09-01

Long-term interleukin-33 treatment delays disease onset and alleviates astrocytic activation in a transgenic mouse model of amyotrophic lateral sclerosis

by Paula Korhonen, Eveliina Pollari, Katja M. Kanninen, Ekaterina Savchenko, Šárka Lehtonen, Sara Wojciechowski, Yuriy Pomeshchik, Ludo Van Den Bosch, Gundars Goldsteins, Jari Koistinaho, Tarja Malm
Published 2019-06-01

Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis

by Haibo Wang, Wenting Guo, Joy Mitra, Pavana M. Hegde, Tijs Vandoorne, Bradley J. Eckelmann, Sankar Mitra, Alan E. Tomkinson, Ludo Van Den Bosch, Muralidhar L. Hegde
Published 2018-09-01

A generic approach to study the kinetics of liquid–liquid phase separation under near-native conditions

by Joris Van Lindt, Anna Bratek-Skicki, Phuong N. Nguyen, Donya Pakravan, Luis F. Durán-Armenta, Agnes Tantos, Rita Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
Published 2021-01-01

Author Correction: A generic approach to study the kinetics of liquid–liquid phase separation under near-native conditions

by Joris Van Lindt, Anna Bratek-Skicki, Phuong N. Nguyen, Donya Pakravan, Luis F. Durán-Armenta, Agnes Tantos, Rita Pancsa, Ludo Van Den Bosch, Dominique Maes, Peter Tompa
Published 2021-03-01

Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model

by Chloë Goossens, Ruben Weckx, Sarah Derde, Lawrence Van Helleputte, Dominik Schneidereit, Michael Haug, Barbara Reischl, Oliver Friedrich, Ludo Van Den Bosch, Greet Van den Berghe, Lies Langouche
Published 2021-04-01