The ambiguous base-pairing and high substrate efficiency of T-705 (Favipiravir) Ribofuranosyl 5'-triphosphate towards influenza A virus polymerase.

by Zhinan Jin, Lucas K Smith, Vivek K Rajwanshi, Baek Kim, Jerome Deval
Published 2013-01-01

MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling.

by Karin Lin, Gregor Bieri, Geraldine Gontier, Sören Müller, Lucas K Smith, Cedric E Snethlage, Charles W White, Sun Y Maybury-Lewis, Saul A Villeda
Published 2021-06-01

Mef2C restrains microglial inflammatory response and is lost in brain ageing in an IFN-I-dependent manner

by Aleksandra Deczkowska, Orit Matcovitch-Natan, Afroditi Tsitsou-Kampeli, Sefi Ben-Hamo, Raz Dvir-Szternfeld, Amit Spinrad, Oded Singer, Eyal David, Deborah R. Winter, Lucas K. Smith, Alexander Kertser, Kuti Baruch, Neta Rosenzweig, Anna Terem, Marco Prinz, Saul Villeda, Ami Citri, Ido Amit, Michal Schwartz
Published 2017-09-01

Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate.

by Jerome Deval, Jin Hong, Guangyi Wang, Josh Taylor, Lucas K Smith, Amy Fung, Sarah K Stevens, Hong Liu, Zhinan Jin, Natalia Dyatkina, Marija Prhavc, Antitsa D Stoycheva, Vladimir Serebryany, Jyanwei Liu, David B Smith, Yuen Tam, Qingling Zhang, Martin L Moore, Rachel Fearns, Sushmita M Chanda, Lawrence M Blatt, Julian A Symons, Leo Beigelman
Published 2015-06-01