Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects.

by Matthew W McClure, Elina Berliba, Tengiz Tsertsvadze, Adrian Streinu-Cercel, Leen Vijgen, Béatrice Astruc, Alain Patat, Christopher Westland, Sushmita Chanda, Qingling Zhang, Thomas N Kakuda, Jennifer Vuong, Nick Khorlin, Leonid Beigelman, Lawrence M Blatt, John Fry
Published 2018-01-01

Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH).

by Xuan G Luong, Sarah K Stevens, Andreas Jekle, Tse-I Lin, Kusum Gupta, Dinah Misner, Sushmita Chanda, Sucheta Mukherjee, Caroline Williams, Antitsa Stoycheva, Lawrence M Blatt, Leonid N Beigelman, Julian A Symons, Pierre Raboisson, David McGowan, Koen Vandyck, Jerome Deval
Published 2020-01-01

Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate.

by Jerome Deval, Jin Hong, Guangyi Wang, Josh Taylor, Lucas K Smith, Amy Fung, Sarah K Stevens, Hong Liu, Zhinan Jin, Natalia Dyatkina, Marija Prhavc, Antitsa D Stoycheva, Vladimir Serebryany, Jyanwei Liu, David B Smith, Yuen Tam, Qingling Zhang, Martin L Moore, Rachel Fearns, Sushmita M Chanda, Lawrence M Blatt, Julian A Symons, Leo Beigelman
Published 2015-06-01