Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling.

by Lorenza A D'Alessandro, Regina Samaga, Tim Maiwald, Seong-Hwan Rho, Sandra Bonefas, Andreas Raue, Nao Iwamoto, Alexandra Kienast, Katharina Waldow, Rene Meyer, Marcel Schilling, Jens Timmer, Steffen Klamt, Ursula Klingmüller
Published 2015-04-01

Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration

by Rene eMeyer, Lorenza A D`Alessandro, Sandip eKar, Sandip eKar, Bernhard eKramer, Bin eShe, Daniel eKaschek, Bettina eHahn, David eWrangborg, Johan eKarlsson, Mats eKvarnstrom, Mats eJirstrand, Wolf-Dieter eLehmann, Jens eTimmer, Jens eTimmer, Jens eTimmer, Jens eTimmer, Jens eTimmer, Thomas eHöfer, Thomas eHöfer, Ursula eKlingmüller, Ursula eKlingmüller
Published 2012-11-01

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib

by Svantje Sobotta, Andreas Raue, Xiaoyun Huang, Joep Vanlier, Joep Vanlier, Anja Jünger, Sebastian Bohl, Ute Albrecht, Maximilian J. Hahnel, Stephanie Wolf, Nikola S. Mueller, Lorenza A. D'Alessandro, Stephanie Mueller-Bohl, Martin E. Boehm, Philippe Lucarelli, Sandra Bonefas, Georg Damm, Daniel Seehofer, Wolf D. Lehmann, Stefan Rose-John, Frank van der Hoeven, Norbert Gretz, Fabian J. Theis, Fabian J. Theis, Christian Ehlting, Johannes G. Bode, Jens Timmer, Jens Timmer, Marcel Schilling, Ursula Klingmüller
Published 2017-10-01