Cell-Intrinsic Roles for Autophagy in Modulating CD4 T Cell Functions

by Elise Jacquin, Elise Jacquin, Lionel Apetoh, Lionel Apetoh
Published 2018-05-01

Can Immunogenic Chemotherapies Relieve Cancer Cell Resistance to Immune Checkpoint Inhibitors?

by Thaiz Rivera Vargas, Thaiz Rivera Vargas, Lionel Apetoh, Lionel Apetoh
Published 2019-05-01

Enhancing the anticancer effects of 5-fluorouracil: Current challenges and future perspectives

by François Ghiringhelli, Lionel Apetoh
Published 2015-04-01

Modulation of Determinant Factors to Improve Therapeutic Combinations with Immune Checkpoint Inhibitors

by Magalie Dosset, Elodie Lauret-Marie Joseph, Thaiz Rivera Vargas, Lionel Apetoh
Published 2020-07-01

The 6th R of Radiobiology: Reactivation of Anti-Tumor Immune Response

by Jihane Boustani, Mathieu Grapin, Pierre-Antoine Laurent, Lionel Apetoh, Céline Mirjolet
Published 2019-06-01

Trial Watch: Adoptively transferred cells for anticancer immunotherapy

by Carole Fournier, François Martin, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi, Lionel Apetoh
Published 2017-11-01

Prospective study of the evolution of blood lymphoid immune parameters during dacarbazine chemotherapy in metastatic and locally advanced melanoma patients.

by Grégoire Mignot, Alice Hervieu, Pierre Vabres, Sophie Dalac, Geraldine Jeudy, Blandine Bel, Lionel Apetoh, François Ghiringhelli
Published 2014-01-01

Signalling strength determines proapoptotic functions of STING

by Muhammet F. Gulen, Ute Koch, Simone M. Haag, Fabian Schuler, Lionel Apetoh, Andreas Villunger, Freddy Radtke, Andrea Ablasser
Published 2017-09-01

IL-27-Induced Type 1 Regulatory T-Cells Produce Oxysterols that Constrain IL-10 Production

by Solenne Vigne, Fanny Chalmin, Donovan Duc, Aurélie S. Clottu, Lionel Apetoh, Jean-Marc A. Lobaccaro, Isabelle Christen, Juan Zhang, Caroline Pot, Caroline Pot
Published 2017-09-01

Selective degradation of PU.1 during autophagy represses the differentiation and antitumour activity of TH9 cells

by Thaiz Rivera Vargas, Zhijian Cai, Yingying Shen, Magalie Dosset, Isis Benoit-Lizon, Tiffany Martin, Aurélie Roussey, Richard A. Flavell, François Ghiringhelli, Lionel Apetoh
Published 2017-09-01

Bleomycin exerts ambivalent antitumor immune effect by triggering both immunogenic cell death and proliferation of regulatory T cells.

by Hélène Bugaut, Mélanie Bruchard, Hélène Berger, Valentin Derangère, Ludivine Odoul, Romain Euvrard, Sylvain Ladoire, Fanny Chalmin, Frédérique Végran, Cédric Rébé, Lionel Apetoh, François Ghiringhelli, Grégoire Mignot
Published 2013-01-01

Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation

by Emeric Limagne, Marion Thibaudin, Romain Euvrard, Hélène Berger, Pauline Chalons, Frédérique Végan, Etienne Humblin, Romain Boidot, Cédric Rébé, Valentin Derangère, Sylvain Ladoire, Lionel Apetoh, Dominique Delmas, François Ghiringhelli
Published 2017-04-01

IRF8-dependent molecular complexes control the Th9 transcriptional program

by Etienne Humblin, Marion Thibaudin, Fanny Chalmin, Valentin Derangère, Emeric Limagne, Corentin Richard, Richard A. Flavell, Sandy Chevrier, Sylvain Ladoire, Hélène Berger, Romain Boidot, Lionel Apetoh, Frédérique Végran, François Ghiringhelli
Published 2017-12-01

Fas signaling-mediated TH9 cell differentiation favors bowel inflammation and antitumor functions

by Yingying Shen, Zhengbo Song, Xinliang Lu, Zeyu Ma, Chaojie Lu, Bei Zhang, Yinghu Chen, Meng Duan, Lionel Apetoh, Xu Li, Jufeng Guo, Ying Miao, Gensheng Zhang, Diya Yang, Zhijian Cai, Jianli Wang
Published 2019-07-01

PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer

by Magalie Dosset, Thaiz Rivera Vargas, Anaïs Lagrange, Romain Boidot, Frédérique Végran, Aurélie Roussey, Fanny Chalmin, Lucile Dondaine, Catherine Paul, Elodie Lauret Marie-Joseph, François Martin, Bernhard Ryffel, Christophe Borg, Olivier Adotévi, François Ghiringhelli, Lionel Apetoh
Published 2018-06-01

Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondria...

by Wafa Zeriouh, Abdelhafid Nani, Meriem Belarbi, Adélie Dumont, Charlotte de Rosny, Ikram Aboura, Fatima Zahra Ghanemi, Babar Murtaza, Danish Patoli, Charles Thomas, Lionel Apetoh, Cédric Rébé, Dominique Delmas, Naim Akhtar Khan, François Ghiringhelli, Mickael Rialland, Aziz Hichami
Published 2017-01-01

Correction: Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the...

by Wafa Zeriouh, Abdelhafid Nani, Meriem Belarbi, Adélie Dumont, Charlotte de Rosny, Ikram Aboura, Fatima Zahra Ghanemi, Babar Murtaza, Danish Patoli, Charles Thomas, Lionel Apetoh, Cédric Rébé, Dominique Delmas, Naim Akhtar Khan, François Ghiringhelli, Mickael Rialland, Aziz Hichami
Published 2017-01-01

Carob leaf polyphenols trigger intrinsic apoptotic pathway and induce cell cycle arrest in colon cancer cells

by Fatima Zahra Ghanemi, Meriem Belarbi, Aurélie Fluckiger, Abdelhafid Nani, Adélie Dumont, Charlotte De Rosny, Ikram Aboura, Amira Sayed Khan, Babar Murtaza, Chahid Benammar, Boucif Farid Lahfa, Danish Patoli, Dominique Delmas, Cédric Rébé, Lionel Apétoh, Naim Akhtar Khan, François Ghringhelli, Mickael Rialland, Aziz Hichami
Published 2017-06-01

STING-dependent sensing of self-DNA drives silica-induced lung inflammation

by Sulayman Benmerzoug, Stéphanie Rose, Badreddine Bounab, David Gosset, Laure Duneau, Pauline Chenuet, Lucile Mollet, Marc Le Bert, Christopher Lambers, Silvana Geleff, Michael Roth, Louis Fauconnier, Delphine Sedda, Clarisse Carvalho, Olivier Perche, David Laurenceau, Bernhard Ryffel, Lionel Apetoh, Ahmet Kiziltunc, Hakan Uslu, Fadime Sultan Albez, Metin Akgun, Dieudonnée Togbe, Valerie F. J. Quesniaux
Published 2018-12-01

Author Correction: Crizotinib-induced immunogenic cell death in non-small cell lung cancer

by Peng Liu, Liwei Zhao, Jonathan Pol, Sarah Levesque, Adriana Petrazzuolo, Christina Pfirschke, Camilla Engblom, Steffen Rickelt, Takahiro Yamazaki, Kristina Iribarren, Laura Senovilla, Lucillia Bezu, Erika Vacchelli, Valentina Sica, Andréa Melis, Tiffany Martin, Lin Xia, Heng Yang, Qingqing Li, Jinfeng Chen, Sylvère Durand, Fanny Aprahamian, Deborah Lefevre, Sophie Broutin, Angelo Paci, Amaury Bongers, Veronique Minard-Colin, Eric Tartour, Laurence Zitvogel, Lionel Apetoh, Yuting Ma, Mikael J. Pittet, Oliver Kepp, Guido Kroemer
Published 2019-04-01