Immunogenic Cell Death and Elimination of Immunosuppressive Cells: A Double-Edged Sword of Chemotherapy

by Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Francois Ghiringhelli
Published 2020-09-01

Resveratrol Interferes with IL1-β-Induced Pro-Inflammatory Paracrine Interaction between Primary Chondrocytes and Macrophages

by Emeric Limagne, Allan Lançon, Dominique Delmas, Mustapha Cherkaoui-Malki, Norbert Latruffe
Published 2016-05-01

Precision medicine phase II study evaluating the efficacy of a double immunotherapy by durvalumab and tremelimumab combined with olaparib in patients with solid cancers and carrier...

by Jean-David Fumet, Emeric Limagne, Marion Thibaudin, Caroline Truntzer, Aurélie Bertaut, Emilie Rederstorff, Francois Ghiringhelli
Published 2020-08-01

Tim-3/galectin-9 pathway and mMDSC control primary and secondary resistances to PD-1 blockade in lung cancer patients

by Emeric Limagne, Corentin Richard, Marion Thibaudin, Jean-David Fumet, Caroline Truntzer, Aurélie Lagrange, Laure Favier, Bruno Coudert, François Ghiringhelli
Published 2019-04-01

Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response to PD-1/PD-L1 immune checkpoint blockers

by Soleine Medjebar, Caroline Truntzer, Anaïs Perrichet, Emeric Limagne, Jean-David Fumet, Corentin Richard, Arielle Elkrief, Bertrand Routy, Cédric Rébé, François Ghiringhelli
Published 2020-01-01

Impact of proton therapy on antitumor immune response

by Céline Mirjolet, Anaïs Nicol, Emeric Limagne, Carole Mura, Corentin Richard, Véronique Morgand, Marc Rousseau, Romain Boidot, François Ghiringhelli, Georges Noel, Hélène Burckel
Published 2021-06-01

Fluorouracil and bevacizumab plus anakinra for patients with metastatic colorectal cancer refractory to standard therapies (IRAFU): a single-arm phase 2 study

by Nicolas Isambert, Alice Hervieu, Cedric Rébé, Audrey Hennequin, Christophe Borg, Sylvie Zanetta, Angélique Chevriaux, Corentin Richard, Valentin Derangère, Emeric Limagne, Julie Blanc, Aurélie Bertaut, François Ghiringhelli
Published 2018-09-01

Immune classifications with cytotoxic CD8+ and Th17 infiltrates are predictors of clinical prognosis in glioblastoma

by Rachid Madkouri, Coureche Guillaume Kaderbhai, Aurélie Bertaut, Caroline Truntzer, Julie Vincent, Marie Hélene Aubriot-Lorton, Walid Farah, Emeric Limagne, Sylvain Ladoire, Romain Boidot, Valentin Derangère, François Ghiringhelli
Published 2017-06-01

Lysophosphatidylcholine acyltransferase 2-mediated lipid droplet production supports colorectal cancer chemoresistance

by Alexia Karen Cotte, Virginie Aires, Maxime Fredon, Emeric Limagne, Valentin Derangère, Marion Thibaudin, Etienne Humblin, Alessandra Scagliarini, Jean-Paul Pais de Barros, Patrick Hillon, François Ghiringhelli, Dominique Delmas
Published 2018-01-01

Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination

by Mathieu Grapin, Corentin Richard, Emeric Limagne, Romain Boidot, Véronique Morgand, Aurélie Bertaut, Valentin Derangere, Pierre-Antoine Laurent, Marion Thibaudin, Jean David Fumet, Gilles Crehange, François Ghiringhelli, Céline Mirjolet
Published 2019-06-01

Sirtuin-1 Activation Controls Tumor Growth by Impeding Th17 Differentiation via STAT3 Deacetylation

by Emeric Limagne, Marion Thibaudin, Romain Euvrard, Hélène Berger, Pauline Chalons, Frédérique Végan, Etienne Humblin, Romain Boidot, Cédric Rébé, Valentin Derangère, Sylvain Ladoire, Lionel Apetoh, Dominique Delmas, François Ghiringhelli
Published 2017-04-01

IRF8-dependent molecular complexes control the Th9 transcriptional program

by Etienne Humblin, Marion Thibaudin, Fanny Chalmin, Valentin Derangère, Emeric Limagne, Corentin Richard, Richard A. Flavell, Sandy Chevrier, Sylvain Ladoire, Hélène Berger, Romain Boidot, Lionel Apetoh, Frédérique Végran, François Ghiringhelli
Published 2017-12-01

Response to first line chemotherapy regimen is associated with efficacy of nivolumab in non-small-cell lung cancer

by Courèche-Guillaume Kaderbhai, Corentin Richard, Jean David Fumet, Anne Aarnink, Sandra Ortiz-Cuaran, Maurice Pérol, Pascal Foucher, Bruno Coudert, Laure Favier, Aurélie Lagrange, Emeric Limagne, Romain Boidot, Sylvain Ladoire, Michel Poudenx, Marius Ilie, Paul Hofman, Pierre Saintigny, François Ghiringhelli
Published 2017-09-01

Baseline Splenic Volume as a Prognostic Biomarker of FOLFIRI Efficacy and a Surrogate Marker of MDSC Accumulation in Metastatic Colorectal Carcinoma

by Julie Niogret, Emeric Limagne, Marion Thibaudin, Julie Blanc, Aurelie Bertaut, Karine Le Malicot, Yves Rinaldi, François-Xavier Caroli-Bosc, Franck Audemar, Suzanne Nguyen, Corinne Sarda, Catherine Lombard-Bohas, Christophe Locher, Miguel Carreiro, Jean-Louis Legoux, Pierre-Luc Etienne, Mathieu Baconnier, Marc Porneuf, Thomas Aparicio, Francois Ghiringhelli
Published 2020-05-01