Microglia in Alzheimer's Disease

by Lee-Way Jin
Published 2012-01-01

1700 nm optical coherence microscopy enables minimally invasive, label-free, in vivo optical biopsy deep in the mouse brain

by Jun Zhu, Hercules Rezende Freitas, Izumi Maezawa, Lee-way Jin, Vivek J. Srinivasan
Published 2021-07-01

Niemann-Pick Disease Type C Yields Possible Clue for Why Cerebellar Neurons Do Not Form Neurofibrillary Tangles

by Bitao Bu, Hans Klunemann, Kinuko Suzuki, Jin Li, Thomas Bird, Lee-Way Jin, Inez Vincent
Published 2002-11-01

Widespread distribution of PLTP in human CNS: evidence for PLTP synthesis by glia and neurons, and increased levels in Alzheimer's disease

by Simona Vuletic, Lee-Way Jin, Santica M. Marcovina, Elaine R. Peskind, Thomas Mo¨ller, John J. Albers
Published 2003-06-01

Interpretable classification of Alzheimer’s disease pathologies with a convolutional neural network pipeline

by Ziqi Tang, Kangway V. Chuang, Charles DeCarli, Lee-Way Jin, Laurel Beckett, Michael J. Keiser, Brittany N. Dugger
Published 2019-05-01

A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta

by Silvia Hilt, Robin Altman, Tamás Kálai, Izumi Maezawa, Qizhi Gong, Sebastian Wachsmann-Hogiu, Lee-Way Jin, John C. Voss
Published 2018-08-01

Defective GABAergic neurotransmission in the nucleus tractus solitarius in Mecp2-null mice, a model of Rett syndrome

by Chao-Yin Chen, Jacopo Di Lucente, Yen-Chu Lin, Cheng-Chang Lien, Michael A. Rogawski, Izumi Maezawa, Lee-Way Jin
Published 2018-01-01

HDAC1 dysregulation induces aberrant cell cycle and DNA damage in progress of TDP‐43 proteinopathies

by Cheng‐Chun Wu, Lee‐Way Jin, I‐Fang Wang, Wei‐Yen Wei, Pei‐Chuan Ho, Yu‐Chih Liu, Kuen‐Jer Tsai
Published 2020-06-01

Dysregulated bile acid receptor-mediated signaling and IL-17A induction are implicated in diet-associated hepatic health and cognitive function

by Prasant Kumar Jena, Lili Sheng, Michelle Nguyen, Jacopo Di Lucente, Ying Hu, Yongchun Li, Izumi Maezawa, Lee-Way Jin, Yu-Jui Yvonne Wan
Published 2020-11-01

TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s disease

by Yao-Hsiang Shih, Ling-Hsien Tu, Ting-Yu Chang, Kiruthika Ganesan, Wei-Wei Chang, Pao-Sheng Chang, Yu-Sheng Fang, Yeh-Tung Lin, Lee-Way Jin, Yun-Ru Chen
Published 2020-11-01

The influence of spin-labeled fluorene compounds on the assembly and toxicity of the aβ peptide.

by Jitka Petrlova, Tamás Kálai, Izumi Maezawa, Robin Altman, Ghimire Harishchandra, Hyun-Seok Hong, Daniel A Bricarello, Atul N Parikh, Gary A Lorigan, Lee-Way Jin, Kálmán Hideg, John C Voss
Published 2012-01-01

Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort

by Sang Won Seo, Nagehan Ayakta, Lea T. Grinberg, Sylvia Villeneuve, Manja Lehmann, Bruce Reed, Charles DeCarli, Bruce L. Miller, Howard J. Rosen, Adam L. Boxer, James P. O’Neil, Lee-Way Jin, William W. Seeley, William J. Jagust, Gil D. Rabinovici
Published 2017-01-01

Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

by Ching-Pang Chang, Ya-Gin Chang, Pei-Yun Chuang, Thi Ngoc Anh Nguyen, Kuo-Chen Wu, Fang-Yi Chou, Sin-Jhong Cheng, Hui-Mei Chen, Lee-Way Jin, Kevin Carvalho, Vincent Huin, Luc Buée, Yung-Feng Liao, Chun-Jung Lin, David Blum, Yijuang Chern
Published 2021-06-01

Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease

by Liang Zhang, Song Zhang, Izumi Maezawa, Sergey Trushin, Paras Minhas, Matthew Pinto, Lee-Way Jin, Keshar Prasain, Thi D.T. Nguyen, Yu Yamazaki, Takahisa Kanekiyo, Guojun Bu, Benjamin Gateno, Kyeong-Ok Chang, Karl A. Nath, Emirhan Nemutlu, Petras Dzeja, Yuan-Ping Pang, Duy H. Hua, Eugenia Trushina
Published 2015-04-01

Comprehensive analysis of diverse low-grade neuroepithelial tumors with FGFR1 alterations reveals a distinct molecular signature of rosette-forming glioneuronal tumor

by Calixto-Hope G. Lucas, Rohit Gupta, Pamela Doo, Julieann C. Lee, Cathryn R. Cadwell, Biswarathan Ramani, Jeffrey W. Hofmann, Emily A. Sloan, Bette K. Kleinschmidt-DeMasters, Han S. Lee, Matthew D. Wood, Marjorie Grafe, Donald Born, Hannes Vogel, Shahriar Salamat, Diane Puccetti, David Scharnhorst, David Samuel, Tabitha Cooney, Elaine Cham, Lee-way Jin, Ziad Khatib, Ossama Maher, Gabriel Chamyan, Carole Brathwaite, Serguei Bannykh, Sabine Mueller, Cassie N. Kline, Anu Banerjee, Alyssa Reddy, Jennie W. Taylor, Jennifer L. Clarke, Nancy Ann Oberheim Bush, Nicholas Butowski, Nalin Gupta, Kurtis I. Auguste, Peter P. Sun, Jarod L. Roland, Corey Raffel, Manish K. Aghi, Philip Theodosopoulos, Edward Chang, Shawn Hervey-Jumper, Joanna J. Phillips, Melike Pekmezci, Andrew W. Bollen, Tarik Tihan, Susan Chang, Mitchel S. Berger, Arie Perry, David A. Solomon
Published 2020-08-01