GD2-directed bispecific trifunctional antibody outperforms dinutuximab beta in a murine model for aggressive metastasized neuroblastoma

by Annette Künkele, Angelika Eggert, Johannes H Schulte, Anika Klaus, Horst Lindhofer, Felix Zirngibl, Sara M Ivasko, Laura Grunewald, Silke Schwiebert, Peter Ruf, Kathy Astrahantseff, Lena Andersch, Holger N Lode, Kathleen Anders, Patrick Hundsdoerfer
Published 2021-07-01

CD28 Co-Stimulus Achieves Superior CAR T Cell Effector Function against Solid Tumors Than 4-1BB Co-Stimulus

by Ana Textor, Laura Grunewald, Kathleen Anders, Anika Klaus, Silke Schwiebert, Annika Winkler, Maria Stecklum, Jana Rolff, Anton G. Henssen, Uta E. Höpken, Angelika Eggert, Johannes H. Schulte, Michael C. Jensen, Thomas Blankenstein, Annette Künkele
Published 2021-03-01

CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing

by Lena Andersch, Josefine Radke, Anika Klaus, Silke Schwiebert, Annika Winkler, Elisa Schumann, Laura Grunewald, Felix Zirngibl, Carina Flemmig, Michael C. Jensen, Claudia Rossig, Antonia Joussen, Anton Henssen, Angelika Eggert, Johannes H. Schulte, Annette Künkele
Published 2019-09-01

A Reproducible Bioprinted 3D Tumor Model Serves as a Preselection Tool for CAR T Cell Therapy Optimization

by Laura Grunewald, Laura Grunewald, Tobias Lam, Tobias Lam, Lena Andersch, Anika Klaus, Silke Schwiebert, Annika Winkler, Anton Gauert, Anja I. Heeren-Hagemann, Kathy Astrahantseff, Filippos Klironomos, Alexander Thomas, Alexander Thomas, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Anton G. Henssen, Anton G. Henssen, Angelika Eggert, Angelika Eggert, Angelika Eggert, Angelika Eggert, Johannes H. Schulte, Johannes H. Schulte, Johannes H. Schulte, Kathleen Anders, Kathleen Anders, Lutz Kloke, Lutz Kloke, Annette Künkele, Annette Künkele, Annette Künkele, Annette Künkele
Published 2021-06-01

Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy

by Solin Ali, Karin Toews, Silke Schwiebert, Anika Klaus, Annika Winkler, Laura Grunewald, Lena Oevermann, Lena Oevermann, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Alicia Tüns, Michael C. Jensen, Michael C. Jensen, Michael C. Jensen, Anton G. Henssen, Anton G. Henssen, Angelika Eggert, Angelika Eggert, Angelika Eggert, Angelika Eggert, Johannes H. Schulte, Johannes H. Schulte, Johannes H. Schulte, Esther Schwich, Vera Rebmann, Alexander Schramm, Annette Künkele, Annette Künkele, Annette Künkele, Annette Künkele
Published 2020-03-01