Inhibiting PHGDH with NCT-503 reroutes glucose-derived carbons into the TCA cycle, independently of its on-target effect

by Birte Arlt, Guido Mastrobuoni, Jasmin Wuenschel, Kathy Astrahantseff, Angelika Eggert, Stefan Kempa, Hedwig E. Deubzer
Published 2021-01-01

Sinusoidal Obstruction Syndrome Following Myeloablative Therapy and Tranexamic Acid Treatment for Hemorrhage in Two Patients with Neuroblastoma

by Felix Zirngibl, Carina Flemmig, Peter Lang, Annette Künkele, Angelika Eggert, Johannes H. Schulte, Hedwig E. Deubzer
Published 2020-10-01

Tumor-Derived Extracellular Vesicles Impair CD171-Specific CD4+ CAR T Cell Efficacy

by Solin Ali, Karin Toews, Silke Schwiebert, Anika Klaus, Annika Winkler, Laura Grunewald, Lena Oevermann, Lena Oevermann, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Alicia Tüns, Michael C. Jensen, Michael C. Jensen, Michael C. Jensen, Anton G. Henssen, Anton G. Henssen, Angelika Eggert, Angelika Eggert, Angelika Eggert, Angelika Eggert, Johannes H. Schulte, Johannes H. Schulte, Johannes H. Schulte, Esther Schwich, Vera Rebmann, Alexander Schramm, Annette Künkele, Annette Künkele, Annette Künkele, Annette Künkele
Published 2020-03-01

A Reproducible Bioprinted 3D Tumor Model Serves as a Preselection Tool for CAR T Cell Therapy Optimization

by Laura Grunewald, Laura Grunewald, Tobias Lam, Tobias Lam, Lena Andersch, Anika Klaus, Silke Schwiebert, Annika Winkler, Anton Gauert, Anja I. Heeren-Hagemann, Kathy Astrahantseff, Filippos Klironomos, Alexander Thomas, Alexander Thomas, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Hedwig E. Deubzer, Anton G. Henssen, Anton G. Henssen, Angelika Eggert, Angelika Eggert, Angelika Eggert, Angelika Eggert, Johannes H. Schulte, Johannes H. Schulte, Johannes H. Schulte, Kathleen Anders, Kathleen Anders, Lutz Kloke, Lutz Kloke, Annette Künkele, Annette Künkele, Annette Künkele, Annette Künkele
Published 2021-06-01

Clinical Presentation and Management of a Dinutuximab Beta Extravasation in a Patient with Neuroblastoma

by Michael Launspach, Marita Seif, Theresa M. Thole, Patrick Jesse, Joachim Schulz, Johannes H. Schulte, Susan Bischoff, Angelika Eggert, Hedwig E. Deubzer
Published 2021-01-01

Germline Mutations Including the Rare Pathogenic Variant c.3206delC in the <i>ATM</i> Gene Cause Ataxia Teleangiectasia-Associated Primary Central Nervous System Lymphoma

by Jan R. Dörr, Anne Thorwarth, Agnieszka Mizia-Malarz, Josefine Radke, Anna Tietze, Pablo Hernáiz-Driever, Denise Horn, Alexander Gratopp, Angelika Eggert, Hedwig E. Deubzer
Published 2021-06-01

Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing

by Annabell Szymansky, Louisa-Marie Kruetzfeldt, Lukas C. Heukamp, Falk Hertwig, Jessica Theissen, Hedwig E. Deubzer, Eva-Maria Willing, Roopika Menon, Steffen Fuchs, Theresa Thole, Stefanie Schulte, Karin Schmelz, Annette Künkele, Peter Lang, Jörg Fuchs, Angelika Eggert, Cornelia Eckert, Matthias Fischer, Anton G. Henssen, Elias Rodriguez-Fos, Johannes H. Schulte
Published 2021-07-01