Cyclophilin and Viruses: Cyclophilin as a Cofactor for Viral Infection and Possible Anti-Viral Target

by Koichi Watashi, Kunitada Shimotohno
Published 2007-01-01

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by Koichi Watashi, Kunitada Shimotohno
Published 2007-01-01

Cyclophilin and Viruses: Cyclophilin as a Cofactor for Viral Infection and Possible Anti-Viral Target

by Koichi Watashi, Kunitada Shimotohno Ph.D.
Published 2007-01-01

Critical role of interferon-α constitutively produced in human hepatocytes in response to RNA virus infection.

by Yoji Tsugawa, Hiroki Kato, Takashi Fujita, Kunitada Shimotohno, Makoto Hijikata
Published 2014-01-01

Orchestration of Intracellular Circuits by G Protein-Coupled Receptor 39 for Hepatitis B Virus Proliferation

by Kaku Goto, Hironori Nishitsuji, Masaya Sugiyama, Nao Nishida, Masashi Mizokami, Kunitada Shimotohno
Published 2020-08-01

Does Genetic Predisposition Contribute to the Exacerbation of COVID-19 Symptoms in Individuals with Comorbidities and Explain the Huge Mortality Disparity between the East and the...

by Naoki Yamamoto, Rain Yamamoto, Yasuo Ariumi, Masashi Mizokami, Kunitada Shimotohno, Hiroshi Yoshikura
Published 2021-05-01

Development of mouse hepatocyte lines permissive for hepatitis C virus (HCV).

by Hussein Hassan Aly, Hiroyuki Oshiumi, Hiroaki Shime, Misako Matsumoto, Taka Wakita, Kunitada Shimotohno, Tsukasa Seya
Published 2011-01-01

Hepatitis C virus core protein abrogates the DDX3 function that enhances IPS-1-mediated IFN-beta induction.

by Hiroyuki Oshiumi, Masanori Ikeda, Misako Matsumoto, Ayako Watanabe, Osamu Takeuchi, Shizuo Akira, Nobuyuki Kato, Kunitada Shimotohno, Tsukasa Seya
Published 2010-01-01

The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families.

by Yoshiki Murakami, Hidenori Toyoda, Masami Tanaka, Masahiko Kuroda, Yoshinori Harada, Fumihiko Matsuda, Atsushi Tajima, Nobuyoshi Kosaka, Takahiro Ochiya, Kunitada Shimotohno
Published 2011-01-01

Dysregulation of IFN system can lead to poor response to pegylated interferon and ribavirin therapy in chronic hepatitis C.

by Koji Onomoto, Shiho Morimoto, Takahisa Kawaguchi, Hidenori Toyoda, Masami Tanaka, Masahiko Kuroda, Kazuko Uno, Takashi Kumada, Fumihiko Matsuda, Kunitada Shimotohno, Takashi Fujita, Yoshiki Murakami
Published 2011-01-01

Engineering Cellular Biosensors with Customizable Antiviral Responses Targeting Hepatitis B Virus

by Satoko Matsunaga, Sundararaj S. Jeremiah, Kei Miyakawa, Daisuke Kurotaki, Sayaka Shizukuishi, Koichi Watashi, Hironori Nishitsuji, Hirokazu Kimura, Tomohiko Tamura, Naoki Yamamoto, Kunitada Shimotohno, Takaji Wakita, Akihide Ryo
Published 2020-03-01

Cyclosporin A associated helicase-like protein facilitates the association of hepatitis C virus RNA polymerase with its cellular cyclophilin B.

by Kengo Morohashi, Hiroeki Sahara, Koichi Watashi, Kazuki Iwabata, Takashi Sunoki, Kouji Kuramochi, Kaori Takakusagi, Hiroki Miyashita, Noriyuki Sato, Atsushi Tanabe, Kunitada Shimotohno, Susumu Kobayashi, Kengo Sakaguchi, Fumio Sugawara
Published 2011-04-01

Serum miRNAs Predicting Sustained HBs Antigen Reduction 48 Weeks after Pegylated Interferon Therapy in HBe Antigen-Negative Patients

by Koji Fujita, Shima Mimura, Hisakazu Iwama, Mai Nakahara, Kyoko Oura, Tomoko Tadokoro, Takako Nomura, Joji Tani, Hirohito Yoneyama, Asahiro Morishita, Makoto Oryu, Takashi Himoto, Hironori Nishitsuji, Kunitada Shimotohno, Masao Omata, Tsutomu Masaki
Published 2018-07-01

Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-251

by Youki Ueda, Weilin Gu, Hiromichi Dansako, Hye-Sook Kim, Sayaka Yoshizaki, Nobuaki Okumura, Tomohiro Ishikawa, Hironori Nishitsuji, Fumihiro Kato, Takayuki Hishiki, Shinya Satoh, Koji Ishii, Michiaki Masuda, Kunitada Shimotohno, Masanori Ikeda, Nobuyuki Kato
Published 2018-09-01

Apolipoprotein E is an HIV-1-inducible inhibitor of viral production and infectivity in macrophages.

by Rokeya Siddiqui, Shinya Suzu, Mikinori Ueno, Hesham Nasser, Ryota Koba, Farzana Bhuyan, Osamu Noyori, Sofiane Hamidi, Guojun Sheng, Mariko Yasuda-Inoue, Takayuki Hishiki, Sayaka Sukegawa, Eri Miyagi, Klaus Strebel, Shuzo Matsushita, Kunitada Shimotohno, Yasuo Ariumi
Published 2018-11-01

Self-enhancement of hepatitis C virus replication by promotion of specific sphingolipid biosynthesis.

by Yuichi Hirata, Kazutaka Ikeda, Masayuki Sudoh, Yuko Tokunaga, Akemi Suzuki, Leiyun Weng, Masatoshi Ohta, Yoshimi Tobita, Ken Okano, Kazuhisa Ozeki, Kenichi Kawasaki, Takuo Tsukuda, Asao Katsume, Yuko Aoki, Takuya Umehara, Satoshi Sekiguchi, Tetsuya Toyoda, Kunitada Shimotohno, Tomoyoshi Soga, Masahiro Nishijima, Ryo Taguchi, Michinori Kohara
Published 2012-01-01