CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

by Pybus Brandon S, Sousa Jason C, Jin Xiannu, Ferguson James A, Christian Robert E, Barnhart Rebecca, Vuong Chau, Sciotti Richard J, Reichard Gregory A, Kozar Michael P, Walker Larry A, Ohrt Colin, Melendez Victor
Published 2012-08-01

Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice

by Shackleford David M, Roncal Norma, Norval Suzanne, Read Kevin D, Moon Jay, McCalmont William, Mannila Anne, Lanteri Charlotte, Kozar Michael, Gerena Lucia, Gardner Sean, Caridha Diana, Bhonsle Jayendra, Bathurst Ian, Milner Erin, Dow Geoffrey S, Sousa Jason, Steuten Jessica, White Karen L, Zeng Qiang, Charman Susan A
Published 2011-06-01

Analysis and Prediction of Integrated Kinetic Energy in Atlantic Tropical Cyclones