Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

by Taipale, Mikko, Krykbaeva, Irina, Kayatekin, Can, Westover, Kenneth D, Karras, Georgios I, Lindquist, Susan, Koeva, Martina I
Published 2014

Polyglutamine Expanded Huntingtin Dramatically Alters the Genome-Wide Binding of HSF1

by Riva, Laura, Koeva, Martina I., Yildirim, Ferah, Pirhaji, Leila, Dinesh, Deepika, Mazor, Tali, Duennwald, Martin L., Fraenkel, Ernest
Published 2014

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

by Mendillo, Marc L., Santagata, Sandro, Bell, George W., Hu, Rong, Tamimi, Rulla M, Fraenkel, Ernest, Ince, Tan A., Whitesell, Luke, Lindquist, Susan, Koeva, Martina I
Published 2014

The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

by Scherz-Shouval, Ruth, Santagata, Sandro, Mendillo, Marc L, Sholl, Lynette M, Ben-Aharon, Irit, Beck, Andrew H, Dias-Santagata, Dora, Stemmer, Salomon M, Whitesell, Luke, Koeva, Martina I, Lindquist, Susan
Published 2016

Tight Coordination of Protein Translation and Heat Shock Factor 1 Activation Supports the Anabolic Malignant State

by Santagata, S., Mendillo, Marc L., Subramanian, A., Perley, C. C., Roche, S. P., Wong, B., Narayan, Rajiv, Kwon, H., Golub, Todd R., Porco, J. A., Whitesell, L., Lindquist, Susan, Tang, Yun-Chi, Koeva, Martina I, Amon, Angelika B
Published 2015

Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways

by Khurana, Vikram, Chung, Chee Yeun, Auluck, Pavan K., Fanning, Saranna, Tardiff, Daniel F., Bartels, Theresa, Eichhorn, Stephen W., Benyamini, Hadar, Lou, Yali, Nutter-Upham, Andy, Baru, Valeriya, Freyzon, Yelena, Costanzo, Michael, San Luis, Bryan-Joseph, Schöndorf, David C., Barrasa, M. Inmaculada, Ehsani, Sepehr, Sanjana, Neville, Zhong, Quan, Gasser, Thomas, Bartel, David P., Vidal, Marc, Deleidi, Michela, Boone, Charles, Berger, Bonnie, Lindquist, Susan, Peng, Jian, Koeva, Martina I, Tuncbag, Nurcan, Fraenkel, Ernest
Published 2018