Polyglutamine Expanded Huntingtin Dramatically Alters the Genome-Wide Binding of HSF1

by Riva, Laura, Koeva, Martina I., Yildirim, Ferah, Pirhaji, Leila, Dinesh, Deepika, Mazor, Tali, Duennwald, Martin L., Fraenkel, Ernest
Published 2014

Histone Acetylation and CREB Binding Protein Are Required for Neuronal Resistance against Ischemic Injury

by Yildirim, Ferah, Ji, Shengbo, Kronenberg, Golo, Barco, Angel, Olivares, Roman, Benito, Eva, Dirnagl, Ulrich, Gertz, Karen, Endres, Matthias, Harms, Christoph, Meisel, Andreas
Published 2014

Extensive changes in DNA methylation are associated with expression of mutant huntingtin

by Ng, Christopher W., Yildirim, Ferah, Yap, Soon Ming Micha, Matthews, Bryan, Velez, Patricio J., Labadorf, Adam, Fraenkel, Ernest, Dalin, Simona, Housman, David E
Published 2013

Striatal transcriptome changes linked to drug‐induced repetitive behaviors

by Crittenden, Jill R., Gipson, Theresa A., Smith, Anne C., Bowden, Hilary A., Yildirim, Ferah, Fischer, Kyle B., Yim, Michael, Housman, David E., Graybiel, Ann M.
Published 2022

Early epigenomic and transcriptional changes reveal Elk-1 transcription factor as a therapeutic target in Huntington's disease

by Yildirim, Ferah, Ng, Christopher, Kappes, Vincent, Ehrenberger, Tobias, Rigby, Siobhan K., Stivanello, Victoria, Gipson, Theresa A., Soltis, Anthony R., Vanhoutte, Peter, Caboche, Jocelyne, Housman, David E., Fraenkel, Ernest
Published 2020

Targeting H3K4 trimethylation in Huntington disease

by Ng, Christopher W., Yildirim, Ferah, Labadorf, Adam, Fraenkel, Ernest, Vashishtha, Malini, Kratter, Ian H., Bodai, Laszlo, Song, Wan, Lau, Alice L., Vogel-Ciernia, Annie, Troncosco, Juan, Ross, Christopher A., Bates, Gillian P., Krainc, Dimitri, Sadri-Vakili, Ghazaleh, Finkbeiner, Steven, Marsh, J. Lawrence, Thompson, Leslie M., Wasylenko, Theresa Anne, Housman, David E
Published 2014

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

by HD iPSC Consortium, Lim, Ryan G, Salazar, Lisa L, Wilton, Daniel K, King, Alvin R, Stocksdale, Jennifer T, Sharifabad, Delaram, Lau, L Alice, Stevens, Beth, Reidling, Jack C, Winokur, Sara T, Casale, Malcolm S, Thompson, Leslie M, Pardo, Mónica, Díaz-Barriga, A Gerardo García, Straccia, Marco, Sanders, Phil, Alberch, Jordi, Canals, Josep M, Kaye, Julia A, Dunlap, Mariah, Jo, Lisa, May, Hanna, Mount, Elliot, Anderson-Bergman, Cliff, Haston, Kelly, Finkbeiner, Steven, Allen, Nicholas D, Kemp, Paul J, Atwal, Ranjit Singh, Biagioli, Marta, Gusella, James F, MacDonald, Marcy E, Akimov, Sergey S, Arbez, Nicolas, Stewart, Jacqueline, Ross, Christopher A, Mattis, Virginia B, Tom, Colton M, Mattis, Virginia B, Tom, Colton M, Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N, Kedaigle, Amanda Joy, Wasylenko, Theresa Anne, Yildirim, Ferah, Ng, Christopher W., Milani, Pamela, Housman, David E, Fraenkel, Ernest
Published 2018