Computational translation of genomic responses from experimental model systems to humans.

by Douglas K Brubaker, Elizabeth A Proctor, Kevin M Haigis, Douglas A Lauffenburger
Published 2019-01-01

BAY61-3606 affects the viability of colon cancer cells in a genotype-directed manner.

by Ken S Lau, Tinghu Zhang, Krystle R Kendall, Douglas Lauffenburger, Nathanael S Gray, Kevin M Haigis
Published 2012-01-01

Comparative analysis of radiosensitizers for K-RAS mutant rectal cancers.

by Laura B Kleiman, Angela M Krebs, Stephen Y Kim, Theodore S Hong, Kevin M Haigis
Published 2013-01-01

Oncogenic K-Ras promotes proliferation in quiescent intestinal stem cells

by Jessica J. Gierut, Jesse Lyons, Manasvi S. Shah, Casie Genetti, David T. Breault, Kevin M. Haigis
Published 2015-07-01

The origins and genetic interactions of KRAS mutations are allele- and tissue-specific

by Joshua H. Cook, Giorgio E. M. Melloni, Doga C. Gulhan, Peter J. Park, Kevin M. Haigis
Published 2021-03-01

Multi-scale in vivo systems analysis reveals the influence of immune cells on TNF-α-induced apoptosis in the intestinal epithelium.

by Ken S Lau, Virna Cortez-Retamozo, Sarah R Philips, Mikael J Pittet, Douglas A Lauffenburger, Kevin M Haigis
Published 2012-01-01

Correction: Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium.

by Ken S. Lau, Virna Cortez-Retamozo, Sarah R. Philips, Mikael J. Pittet, Douglas A. Lauffenburger, Kevin M. Haigis
Published 2012-10-01

A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells

by Timothy D. Martin, Danielle R. Cook, Mei Yuk Choi, Mamie Z. Li, Kevin M. Haigis, Stephen J. Elledge
Published 2017-07-01

MAPKAP Kinase-2 Drives Expression of Angiogenic Factors by Tumor-Associated Macrophages in a Model of Inflammation-Induced Colon Cancer

by Lucia Suarez-Lopez, Lucia Suarez-Lopez, Yi Wen Kong, Ganapathy Sriram, Jesse C. Patterson, Samantha Rosenberg, Sandra Morandell, Kevin M. Haigis, Michael B. Yaffe, Michael B. Yaffe
Published 2021-02-01

The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile.

by Jesse Lyons, Phaedra C Ghazi, Alina Starchenko, Alessio Tovaglieri, Katherine R Baldwin, Emily J Poulin, Jessica J Gierut, Casie Genetti, Vijay Yajnik, David T Breault, Douglas A Lauffenburger, Kevin M Haigis
Published 2018-03-01