Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells

by Adrianna K. San Roman, Alessio Tovaglieri, David T. Breault, Ramesh A. Shivdasani
Published 2015-11-01

JAK/STAT-1 Signaling Is Required for Reserve Intestinal Stem Cell Activation during Intestinal Regeneration Following Acute Inflammation

by Camilla A. Richmond, Hannah Rickner, Manasvi S. Shah, Tracy Ediger, Luke Deary, Fanny Zhou, Alessio Tovaglieri, Diana L. Carlone, David T. Breault
Published 2018-01-01

Microfluidic Organ-on-a-Chip Models of Human IntestineSummary

by Amir Bein, Woojung Shin, Sasan Jalili-Firoozinezhad, Min Hee Park, Alexandra Sontheimer-Phelps, Alessio Tovaglieri, Angeliki Chalkiadaki, Hyun Jung Kim, Donald E. Ingber
Published 2018-01-01

The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile.

by Jesse Lyons, Phaedra C Ghazi, Alina Starchenko, Alessio Tovaglieri, Katherine R Baldwin, Emily J Poulin, Jessica J Gierut, Casie Genetti, Vijay Yajnik, David T Breault, Douglas A Lauffenburger, Kevin M Haigis
Published 2018-03-01

Dormant Intestinal Stem Cells Are Regulated by PTEN and Nutritional Status

by Camilla A. Richmond, Manasvi S. Shah, Luke T. Deary, Danny C. Trotier, Horatio Thomas, Dana M. Ambruzs, Lijie Jiang, Bristol B. Whiles, Hannah D. Rickner, Robert K. Montgomery, Alessio Tovaglieri, Diana L. Carlone, David T. Breault
Published 2015-12-01

Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites

by Alessio Tovaglieri, Alexandra Sontheimer-Phelps, Annelies Geirnaert, Rachelle Prantil-Baun, Diogo M. Camacho, David B. Chou, Sasan Jalili-Firoozinezhad, Tomás de Wouters, Magdalena Kasendra, Michael Super, Mark J. Cartwright, Camilla A. Richmond, David T. Breault, Christophe Lacroix, Donald E. Ingber
Published 2019-03-01

Human Colon-on-a-Chip Enables Continuous In Vitro Analysis of Colon Mucus Layer Accumulation and PhysiologySummary

by Alexandra Sontheimer-Phelps, David B. Chou, Alessio Tovaglieri, Thomas C. Ferrante, Taylor Duckworth, Cicely Fadel, Viktoras Frismantas, Arlene D. Sutherland, Sasan Jalili-Firoozinezhad, Magdalena Kasendra, Eric Stas, James C. Weaver, Camilla A. Richmond, Oren Levy, Rachelle Prantil-Baun, David T. Breault, Donald E. Ingber
Published 2020-01-01