A cross-metathesis approach to novel pantothenamide derivatives

by Jinming Guan, Matthew Hachey, Lekha Puri, Vanessa Howieson, Kevin J. Saliba, Karine Auclair
Published 2016-05-01

Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress.

by Donelly A van Schalkwyk, Kevin J Saliba, Giancarlo A Biagini, Patrick G Bray, Kiaran Kirk
Published 2013-01-01

Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.

by Christina Spry, Cristiano Macuamule, Zhiyang Lin, Kristopher G Virga, Richard E Lee, Erick Strauss, Kevin J Saliba
Published 2013-01-01

Human dihydrofolate reductase influences the sensitivity of the malaria parasite Plasmodium falciparum to ketotifen – A cautionary tale in screening transgenic parasites

by Phuong N. Tran, Cameron J. Tate, Melanie C. Ridgway, Kevin J. Saliba, Kiaran Kirk, Alexander G. Maier
Published 2016-12-01

Biological characterization of chemically diverse compounds targeting the Plasmodium falciparum coenzyme A synthesis pathway

by Sabine Fletcher, Leonardo Lucantoni, Melissa L. Sykes, Amy J. Jones, John P. Holleran, Kevin J. Saliba, Vicky M. Avery
Published 2016-11-01

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.

by Erick T Tjhin, Christina Spry, Alan L Sewell, Annabelle Hoegl, Leanne Barnard, Anna E Sexton, Ghizal Siddiqui, Vanessa M Howieson, Alexander G Maier, Darren J Creek, Erick Strauss, Rodolfo Marquez, Karine Auclair, Kevin J Saliba
Published 2018-04-01