Mutations at the hydrophobic core affect Hal3 trimer stability, reducing its Ppz1 inhibitory capacity but not its PPCDC moonlighting function

by Carlos Santolaria, Diego Velázquez, Erick Strauss, Joaquín Ariño
Published 2018-10-01

Vitamin in the Crosshairs: Targeting Pantothenate and Coenzyme A Biosynthesis for New Antituberculosis Agents

by Hailey S. Butman, Timothy J. Kotzé, Cynthia S. Dowd, Erick Strauss
Published 2020-12-01

Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated.

by Christina Spry, Cristiano Macuamule, Zhiyang Lin, Kristopher G Virga, Richard E Lee, Erick Strauss, Kevin J Saliba
Published 2013-01-01

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues.

by Erick T Tjhin, Christina Spry, Alan L Sewell, Annabelle Hoegl, Leanne Barnard, Anna E Sexton, Ghizal Siddiqui, Vanessa M Howieson, Alexander G Maier, Darren J Creek, Erick Strauss, Rodolfo Marquez, Karine Auclair, Kevin J Saliba
Published 2018-04-01