Leupaxin Expression Is Dispensable for B Cell Immune Responses

by Amélie Bonaud, Amélie Bonaud, Simon Clare, Valeria Bisio, John M. Sowerby, John M. Sowerby, Shugang Yao, Hanne Ostergaard, Karl Balabanian, Karl Balabanian, Kenneth G. C. Smith, Kenneth G. C. Smith, Marion Espéli, Marion Espéli
Published 2020-03-01

FcγRIIb differentially regulates pre-immune and germinal center B cell tolerance in mouse and human

by Marion Espéli, Rachael Bashford-Rogers, John M. Sowerby, Nagham Alouche, Limy Wong, Alice E. Denton, Michelle A. Linterman, Kenneth G. C. Smith
Published 2019-04-01

Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease.

by James E Peters, Paul A Lyons, James C Lee, Arianne C Richard, Mary D Fortune, Paul J Newcombe, Sylvia Richardson, Kenneth G C Smith
Published 2016-03-01

Peripheral Immune Cell Populations Associated with Cognitive Deficits and Negative Symptoms of Treatment-Resistant Schizophrenia.

by Emilio Fernandez-Egea, Petra E Vértes, Shaun M Flint, Lorinda Turner, Syed Mustafa, Alex Hatton, Kenneth G C Smith, Paul A Lyons, Edward T Bullmore
Published 2016-01-01

A CD8+ NK cell transcriptomic signature associated with clinical outcome in relapsing remitting multiple sclerosis

by Eoin F. McKinney, Iona Cuthbertson, Kristina M. Harris, Dawn E. Smilek, Christopher Connor, Giulia Manferrari, Edward J. Carr, Scott S. Zamvil, Kenneth G. C. Smith
Published 2021-01-01

Reduced monocyte and macrophage TNFSF15/TL1A expression is associated with susceptibility to inflammatory bowel disease.

by Arianne C Richard, James E Peters, Natalia Savinykh, James C Lee, Eric T Hawley, Françoise Meylan, Richard M Siegel, Paul A Lyons, Kenneth G C Smith
Published 2018-09-01

Combined Influence of B-Cell Receptor Rearrangement and Somatic Hypermutation on B-Cell Class-Switch Fate in Health and in Chronic Lymphocytic Leukemia

by Velislava N. Petrova, Luke Muir, Paul F. McKay, George S. Vassiliou, Kenneth G. C. Smith, Paul A. Lyons, Colin A. Russell, Carl A. Anderson, Paul Kellam, Rachael J. M. Bashford-Rogers
Published 2018-08-01

One Gene, Many Facets: Multiple Immune Pathway Dysregulation in SOCS1 Haploinsufficiency

by Julia Körholz, Julia Körholz, Anastasia Gabrielyan, John M. Sowerby, John M. Sowerby, Felix Boschann, Lan-Sun Chen, Diana Paul, David Brandt, Janina Kleymann, Martin Kolditz, Nicole Toepfner, Ralf Knöfler, Eva-Maria Jacobsen, Christine Wolf, Karsten Conrad, Nadja Röber, Min Ae Lee-Kirsch, Min Ae Lee-Kirsch, Kenneth G. C. Smith, Kenneth G. C. Smith, Stefan Mundlos, Stefan Mundlos, Stefan Mundlos, Stefan Mundlos, Reinhard Berner, Reinhard Berner, Alexander H. Dalpke, Catharina Schuetz, Catharina Schuetz, William Rae, William Rae
Published 2021-08-01

Lipid anti-lipid antibody responses correlate with disease activity in systemic lupus erythematosus.

by Vojislav Jovanović, Nurhuda Abdul Aziz, Yan Ting Lim, Amanda Ng Ai Poh, Sherlynn Jin Hui Chan, Eliza Ho Xin Pei, Fei Chuin Lew, Guanghou Shui, Andrew M Jenner, Li Bowen, Eoin F McKinney, Paul A Lyons, Michael D Kemeny, Kenneth G C Smith, Markus R Wenk, Paul A Macary
Published 2013-01-01

Correction: Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus

by Vojislav Jovanović, Nurhuda Abdul Aziz, Yan Ting Lim, Amanda Ng Ai Poh, Sherlynn Jin Hui Chan, Eliza Ho Xin Pei, Fei Chuin Lew, Guanghou Shui, Andrew M. Jenner, Li Bowen, Eoin F. McKinney, Paul A. Lyons, David M. Kemeny, Kenneth G. C. Smith, Markus R. Wenk, Paul A. MacAry
Published 2013-01-01

Correction: Lipid Anti-Lipid Antibody Responses Correlate with Disease Activity in Systemic Lupus Erythematosus.

by Vojislav Jovanović, Nurhuda Abdul Aziz, Yan Ting Lim, Amanda Ng Ai Poh, Sherlynn Jin Hui Chan, Eliza Ho Xin Pei, Fei Chuin Lew, Guanghou Shui, Andrew M. Jenner, Li Bowen, Eoin F. McKinney, Paul A. Lyons, David M. Kemeny, Kenneth G. C. Smith, Markus R. Wenk, Paul A. MacAry
Published 2013-01-01

Genome-wide association study of eosinophilic granulomatosis with polyangiitis reveals genomic loci stratified by ANCA status

by Paul A Lyons, James E Peters, Federico Alberici, James Liley, Richard M. R. Coulson, William Astle, Chiara Baldini, Francesco Bonatti, Maria C Cid, Heather Elding, Giacomo Emmi, Jörg Epplen, Loïc Guillevin, David R. W. Jayne, Tao Jiang, Iva Gunnarsson, Peter Lamprecht, Stephen Leslie, Mark A. Little, Davide Martorana, Frank Moosig, Thomas Neumann, Sophie Ohlsson, Stefanie Quickert, Giuseppe A. Ramirez, Barbara Rewerska, Georg Schett, Renato A. Sinico, Wojciech Szczeklik, Vladimir Tesar, Damjan Vukcevic, The European Vasculitis Genetics Consortium, Benjamin Terrier, Richard A Watts, Augusto Vaglio, Julia U Holle, Chris Wallace, Kenneth G. C. Smith
Published 2019-11-01

Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study

by Dami A. Collier, Sonny M. Assennato, Ben Warne, Nyarie Sithole, Katherine Sharrocks, Allyson Ritchie, Pooja Ravji, Matthew Routledge, Dominic Sparkes, Jordan Skittrall, Anna Smielewska, Isobel Ramsey, Neha Goel, Martin Curran, David Enoch, Rhys Tassell, Michelle Lineham, Devan Vaghela, Clare Leong, Hoi Ping Mok, John Bradley, Kenneth G.C. Smith, Vivienne Mendoza, Nikos Demiris, Martin Besser, Gordon Dougan, Paul J. Lehner, Mark J. Siedner, Hongyi Zhang, Claire S. Waddington, Helen Lee, Ravindra K. Gupta, Stephen Baker, John Bradley, Gordon Dougan, Ian Goodfellow, Ravindra K. Gupta, Paul J. Lehner, Paul Lyons, Nicholas J. Matheson, Kenneth G.C. Smith, Mark Toshner, Michael P. Weekes, Nick Brown, Martin Curran, Surendra Palmar, Hongyi Zhang, David Enoch, Daniel Chapman, Ashley Shaw, Vivien Mendoza, Sherly Jose, Areti Bermperi, Julie Ann Zerrudo, Evgenia Kourampa, Caroline Saunders, Ranalie de Jesus, Jason Domingo, Ciro Pasquale, Bensi Vergese, Phoebe Vargas, Marivic Fabiculana, Marlyn Perales, Richard Skells, Lee Mynott, Elizabeth Blake, Amy Bates, Anne-laure Vallier, Alexandra Williams, David Phillips, Edmund Chiu, Alex Overhill, Nicola Ramenante, Jamal Sipple, Steven Frost, Helena Knock, Richard Hardy, Emily Foster, Fiona Davidson, Viona Rundell, Purity Bundi, Richmond Abeseabe, Sarah Clark, Isabel Vicente
Published 2020-08-01

Treatment of COVID-19 with remdesivir in the absence of humoral immunity: a case report

by Matthew S. Buckland, James B. Galloway, Caoimhe Nic Fhogartaigh, Luke Meredith, Nicholas M. Provine, Stuart Bloor, Ane Ogbe, Wioleta M. Zelek, Anna Smielewska, Anna Yakovleva, Tiffeney Mann, Laura Bergamaschi, Lorinda Turner, Frederica Mescia, Erik J. M. Toonen, Carl-Philipp Hackstein, Hossain Delowar Akther, Vinicius Adriano Vieira, Lourdes Ceron-Gutierrez, Jimstan Periselneris, Sorena Kiani-Alikhan, Sofia Grigoriadou, Devan Vaghela, Sara E. Lear, M. Estée Török, William L. Hamilton, Joanne Stockton, Josh Quick, Peter Nelson, Michael Hunter, Tanya I. Coulter, Lisa Devlin, CITIID-NIHR COVID-19 BioResource Collaboration, MRC-Toxicology Unit COVID-19 Consortium, John R. Bradley, Kenneth G. C. Smith, Willem H. Ouwehand, Lise Estcourt, Heli Harvala, David J. Roberts, Ian B. Wilkinson, Nick Screaton, Nicholas Loman, Rainer Doffinger, Paul A. Lyons, B. Paul Morgan, Ian G. Goodfellow, Paul Klenerman, Paul J. Lehner, Nicholas J. Matheson, James E. D. Thaventhiran
Published 2020-12-01

Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant

by Petra Mlcochova, Dami Collier, Allyson Ritchie, Sonny M. Assennato, Myra Hosmillo, Neha Goel, Bo Meng, Krishna Chatterjee, Vivien Mendoza, Nigel Temperton, Leo Kiss, Leo C. James, Katarzyna A. Ciazynska, Xiaoli Xiong, John A.G. Briggs, James A. Nathan, Federica Mescia, Laura Bergamaschi, Hongyi Zhang, Petros Barmpounakis, Nikos Demeris, Richard Skells, Paul A. Lyons, John Bradley, Steven Baker, Jean Pierre Allain, Kenneth G.C. Smith, Rachel Bousfield, Michael Wilson, Dominic Sparkes, Glenn Amoroso, Effrosyni Gkrania-Klotsas, Susie Hardwick, Adrian Boyle, Ian Goodfellow, Ravindra K. Gupta, Stephen Baker, John Bradley, Gordon Dougan, Ian Goodfellow, Ravi Gupta, Paul J. Lehner, Paul Lyons, Nicholas J. Matheson, Kenneth G.C. Smith, Mark Toshner, Michael P. Weekes, Nick Brown, Martin Curran, Surendra Palmar, Hongyi Zhang, David Enoch, Daniel Chapman, Ashley Shaw, Sherly Jose, Areti Bermperi, Julie Ann Zerrudo, Evgenia Kourampa, Laura Watson, Jieniean Worsley, Caroline Saunders, Ranalie de Jesus, Jason Domingo, Ciro Pasquale, Bensi Vergese, Phoebe Vargas, Marivic Fabiculana, Marlyn Perales, Lee Mynott, Elizabeth Blake, Amy Bates, Anne-Laure Vallier, Alexandra Williams, David Phillips, Edmund Chiu, Alex Overhill, Nicola Ramenatte, Jamal Sipple, Steven Frost, Helena Knock, Richard Hardy, Emily Foster, Fiona Davidson, Viona Rundell, Purity Bundi, Richmond Abeseabe, Sarah Clark, Isabel Vicente, Laura Watson, Jieniean Worsley, Anne Elmer, Carla Ribeiro, Jenny Kourampa, Sherly Jose, Jane Kennet, Jane Rowlands, Anne Meadows, Criona O’Brien, Rebecca Rastall, Cherry Crucusio, Sarah Hewitt, Jane Price, Jo Calder, Laura Canna, Ashlea Bucke, Hugo Tordesillas, Julie Harris, Valentina Ruffolo, Jason Domingo, Barbara Graves, Helen Butcher, Daniela Caputo, Emma Le Gresley, Benjamin J. Dunmore, Jennifer Martin, Ekaterina Legchenko, Carmen Treacy, Christopher Huang, Jennifer Wood, Rachel Sutcliffe, Josh Hodgson, Joy Shih, Stefan Graf, Zhen Tong, Federica Mescia, Tobias Tilly, Ciara O’Donnell, Kelvin Hunter, Linda Pointon, Nicole Pond, Marta Wylot, Emma Jones, Stuart Fawke, Ben Bullman, Lori Turner, Isobel Jarvis, Ommar Omarjee, Aloka De Sa, Joe Marsden, Ariana Betancourt, Marianne Perera, Maddie Epping, Nathan Richoz, Georgie Bower, Rahul Sharma, Francesca Nice, Oisin Huhn, Stuart Fawke, Natalia Savoinykh Yarkoni, Nika Romashova, Daniel Lewis, Andrew Hinch, Chiara Cossetti, Mateusz Strezlecki, Richard Grenfell, Hannah Stark, Neil Walker, Kathy Stirrups, Nigel Ovington, Eleanor Dewhust, Emily Li, Sofia Papadia, Nathalie Kingston, Andrew Lever, Estee Torok, William Hamilton, Grant Hall, Aminu Jahun, Yasmin Chaudhry, Malte Pinckert, Iliana Georgana, Anna Yakovleva, Laura Caller, Sarah Caddy, Theresa Feltwell, Fahad Khokhar, Luke Meredith, Charlotte Holdcroft, Martin Curran, Surendra Parmar, Nathalie Kingston, Andrew Lever, Estee Torok, William Hamilton, Grant Hall, Aminu Jahun, Yasmin Chaudhry, Malte Pinckert, Iliana Georgana, Anna Yakovleva, Laura Caller, Sarah Caddy, Theresa Feltwell, Fahad Khokhar, Luke Meredith, Charlotte Holdcroft, Martin Curran, Surendra Parmar
Published 2020-09-01