Advances in HIV-1 Vaccine Development

by Yong Gao, Paul F. McKay, Jamie F. S. Mann
Published 2018-04-01

Structural Components for Amplification of Positive and Negative Strand VEEV Splitzicons

by Anna K. Blakney, Paul F. McKay, Robin J. Shattock
Published 2018-07-01

Plasmid DNA Vaccine Co-Immunisation Modulates Cellular and Humoral Immune Responses Induced by Intranasal Inoculation in Mice.

by Deborah F L King, Paul F McKay, Jamie F S Mann, C Bryn Jones, Robin J Shattock
Published 2015-01-01

Mucosal application of gp140 encoding DNA polyplexes to different tissues results in altered immunological outcomes in mice.

by Jamie F S Mann, Paul F McKay, Samantha Arokiasamy, Reeyeshkumar K Patel, John S Tregoning, Robin J Shattock
Published 2013-01-01

TLR4 and TLR7/8 Adjuvant Combinations Generate Different Vaccine Antigen-Specific Immune Outcomes in Minipigs when Administered via the ID or IN Routes.

by Paul F McKay, Deborah F L King, Jamie F S Mann, Guillermo Barinaga, Darrick Carter, Robin J Shattock
Published 2016-01-01

Molecular Signatures of a TLR4 Agonist-Adjuvanted HIV-1 Vaccine Candidate in Humans

by Jenna Anderson, Thorunn A. Olafsdottir, Sven Kratochvil, Paul F. McKay, Malin Östensson, Josefine Persson, Robin J. Shattock, Ali M. Harandi
Published 2018-02-01

Optimisation of ex vivo memory B cell expansion/differentiation for interrogation of rare peripheral memory B cell subset responses [version 2; referees: 2 approved]

by Luke Muir, Paul F. McKay, Velislava N. Petrova, Oleksiy V. Klymenko, Sven Kratochvil, Christopher L. Pinder, Paul Kellam, Robin J. Shattock
Published 2018-01-01

Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination

by Sven Kratochvil, Paul F. McKay, Amy W. Chung, Stephen J. Kent, Stephen J. Kent, Stephen J. Kent, Jill Gilmour, Robin J. Shattock
Published 2017-12-01

Intramuscular Immunisation with Chlamydial Proteins Induces Chlamydia trachomatis Specific Ocular Antibodies.

by Alexander Badamchi-Zadeh, Paul F McKay, Martin J Holland, Wayne Paes, Andrzej Brzozowski, Charles Lacey, Frank Follmann, John S Tregoning, Robin J Shattock
Published 2015-01-01

Corrigendum: Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination

by Sven Kratochvil, Paul F. McKay, Amy W. Chung, Stephen J. Kent, Stephen J. Kent, Stephen J. Kent, Jill Gilmour, Robin J. Shattock
Published 2018-02-01

Glucopyranosyl lipid A adjuvant significantly enhances HIV specific T and B cell responses elicited by a DNA-MVA-protein vaccine regimen.

by Paul F McKay, Alethea V Cope, Jamie F S Mann, Sarah Joseph, Mariano Esteban, Roger Tatoud, Darrick Carter, Steven G Reed, Jonathan Weber, Robin J Shattock
Published 2014-01-01

Identification of potential biomarkers of vaccine inflammation in mice

by Paul F McKay, Deniz Cizmeci, Yoann Aldon, Jeroen Maertzdorf, January Weiner, Stefan HE Kaufmann, David JM Lewis, Robert A van den Berg, Giuseppe Del Giudice, Robin J Shattock
Published 2019-05-01

A multi-component prime-boost vaccination regimen with a consensus MOMP antigen enhances Chlamydia trachomatis clearance.

by Alexander eBadamchi-Zadeh, Paul F. McKay, Bette T. Korber, Guillermo eBarinaga, Adam A. Walters, Alexandra eNunes, João Paulo Gomes, Frank eFollmann, John S. Tregoning, Robin J. Shattock
Published 2016-04-01

Combined Influence of B-Cell Receptor Rearrangement and Somatic Hypermutation on B-Cell Class-Switch Fate in Health and in Chronic Lymphocytic Leukemia

by Velislava N. Petrova, Luke Muir, Paul F. McKay, George S. Vassiliou, Kenneth G. C. Smith, Paul A. Lyons, Colin A. Russell, Carl A. Anderson, Paul Kellam, Rachael J. M. Bashford-Rogers
Published 2018-08-01

Immunogenicity of stabilized HIV-1 Env trimers delivered by self-amplifying mRNA

by Yoann Aldon, Paul F. McKay, Jorge Moreno Herrero, Annette B. Vogel, Réka Lévai, Pauline Maisonnasse, Nathalie Dereuddre-Bosquet, Heinrich Haas, Katalin Fábián, Roger Le Grand, Ugur Sahin, Robin J. Shattock
Published 2021-09-01

Rational Design of DNA-Expressed Stabilized Native-Like HIV-1 Envelope Trimers

by Yoann Aldon, Paul F. McKay, Joel Allen, Gabriel Ozorowski, Réka Felfödiné Lévai, Monica Tolazzi, Paul Rogers, Linling He, Natalia de Val, Katalin Fábián, Gabriella Scarlatti, Jiang Zhu, Andrew B. Ward, Max Crispin, Robin J. Shattock
Published 2018-09-01

Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice

by Paul F. McKay, Kai Hu, Anna K. Blakney, Karnyart Samnuan, Jonathan C. Brown, Rebecca Penn, Jie Zhou, Clément R. Bouton, Paul Rogers, Krunal Polra, Paulo J. C. Lin, Christopher Barbosa, Ying K. Tam, Wendy S. Barclay, Robin J. Shattock
Published 2020-07-01

Heterologous vaccination regimens with self-amplifying RNA and adenoviral COVID vaccines induce robust immune responses in mice

by Alexandra J. Spencer, Paul F. McKay, Sandra Belij-Rammerstorfer, Marta Ulaszewska, Cameron D. Bissett, Kai Hu, Karnyart Samnuan, Anna K. Blakney, Daniel Wright, Hannah R. Sharpe, Ciaran Gilbride, Adam Truby, Elizabeth R. Allen, Sarah C. Gilbert, Robin J. Shattock, Teresa Lambe
Published 2021-05-01

A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost V...

by Sven Kratochvil, Paul F. McKay, Jakub T. Kopycinski, Cynthia Bishop, Peter John Hayes, Luke Muir, Christopher L. Pinder, Deniz Cizmeci, Deborah King, Yoann Aldon, Bruce D. Wines, P. Mark Hogarth, Amy W. Chung, Stephen J. Kent, Stephen J. Kent, Stephen J. Kent, Kathrin Held, Christof Geldmacher, Len Dally, Nelson S. Santos, Tom Cole, Jill Gilmour, Sarah Fidler, Robin J. Shattock
Published 2017-05-01