Regenerative biomarkers for Duchenne muscular dystrophy

by Simon Guiraud, Kay E Davies
Published 2019-01-01

A motor function for the DEAD-box RNA helicase, Gemin3, in Drosophila.

by Ruben J Cauchi, Kay E Davies, Ji-Long Liu
Published 2008-11-01

Survival motor neuron deficiency enhances progression in an amyotrophic lateral sclerosis mouse model

by Bradley J. Turner, Nicholas J. Parkinson, Kay E. Davies, Kevin Talbot
Published 2009-06-01

The Cellular Processing Capacity Limits the Amounts of Chimeric U7 snRNA Available for Antisense Delivery

by Agathe Eckenfelder, Julie Tordo, Arran Babbs, Kay E Davies, Aurélie Goyenvalle, Olivier Danos
Published 2012-01-01

Temporal transcriptomics suggest that twin-peaking genes reset the clock

by William G Pembroke, Arran Babbs, Kay E Davies, Chris P Ponting, Peter L Oliver
Published 2015-11-01

In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy.

by Daniel J Stuckey, Carolyn A Carr, Patrizia Camelliti, Damian J Tyler, Kay E Davies, Kieran Clarke
Published 2012-01-01

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.

by Narinder Janghra, Jennifer E Morgan, Caroline A Sewry, Francis X Wilson, Kay E Davies, Francesco Muntoni, Jonathon Tinsley
Published 2016-01-01

Laf4/Aff3, a gene involved in intellectual disability, is required for cellular migration in the mouse cerebral cortex.

by Justin M Moore, Peter L Oliver, Mattéa J Finelli, Sheena Lee, Tom Lickiss, Zoltán Molnár, Kay E Davies
Published 2014-01-01

Oxr1 is essential for protection against oxidative stress-induced neurodegeneration.

by Peter L Oliver, Mattéa J Finelli, Benjamin Edwards, Emmanuelle Bitoun, Darcy L Butts, Esther B E Becker, Michael T Cheeseman, Ben Davies, Kay E Davies
Published 2011-10-01

Micro-utrophin Improves Cardiac and Skeletal Muscle Function of Severely Affected D2/mdx Mice

by Tahnee L. Kennedy, Simon Guiraud, Ben Edwards, Sarah Squire, Lee Moir, Arran Babbs, Guy Odom, Diane Golebiowski, Joel Schneider, Jeffrey S. Chamberlain, Kay E. Davies
Published 2018-12-01

Alternative splicing events are a late feature of pathology in a mouse model of spinal muscular atrophy.

by Dirk Bäumer, Sheena Lee, George Nicholson, Joanna L Davies, Nicholas J Parkinson, Lyndsay M Murray, Thomas H Gillingwater, Olaf Ansorge, Kay E Davies, Kevin Talbot
Published 2009-12-01

Utrophin up-regulation by an artificial transcription factor in transgenic mice.

by Elisabetta Mattei, Nicoletta Corbi, Maria Grazia Di Certo, Georgios Strimpakos, Cinzia Severini, Annalisa Onori, Agata Desantis, Valentina Libri, Serena Buontempo, Aristide Floridi, Maurizio Fanciulli, Dilair Baban, Kay E Davies, Claudio Passananti
Published 2007-08-01

Preconditioning of Cardiosphere-Derived Cells with Hypoxia or Prolyl-4-Hydroxylase Inhibitors Increases Stemness and Decreases Reliance on Oxidative Metabolism

by Suat Cheng Tan, Renata S. M. Gomes, Kar Kheng Yeoh, Filippo Perbellini, Sophia Malandraki-Miller, Lucy Ambrose, Lisa C. Heather, Giuseppe Faggian, Christopher J. Schofield, Kay E. Davies, Kieran Clarke, Carolyn A. Carr
Published 2016-01-01

Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing

by Laura C.D. Pomatto, Patrick Y. Sun, Kelsi Yu, Sandhyarani Gullapalli, Conscience P. Bwiza, Christina Sisliyan, Sarah Wong, Hongqiao Zhang, Henry Jay Forman, Peter L. Oliver, Kay E. Davies, Kelvin J.A. Davies
Published 2019-06-01

Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression.

by Gianina Ravenscroft, Connie Jackaman, Caroline A Sewry, Elyshia McNamara, Sarah E Squire, Allyson C Potter, John Papadimitriou, Lisa M Griffiths, Anthony J Bakker, Kay E Davies, Nigel G Laing, Kristen J Nowak
Published 2011-01-01

Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse.

by Jonathon M Tinsley, Rebecca J Fairclough, Richard Storer, Fraser J Wilkes, Allyson C Potter, Sarah E Squire, Dave S Powell, Anna Cozzoli, Roberta F Capogrosso, Adam Lambert, Francis X Wilson, Stephen P Wren, Annamaria De Luca, Kay E Davies
Published 2011-05-01

Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse

by Tonya N. Taylor, Dawid Potgieter, Sabina Anwar, Steven L. Senior, Stephanie Janezic, Sarah Threlfell, Brent Ryan, Laura Parkkinen, Thierry Deltheil, Milena Cioroch, Achilleas Livieratos, Peter L. Oliver, Katie A. Jennings, Kay E. Davies, Olaf Ansorge, David M. Bannerman, Stephanie J. Cragg, Richard Wade-Martins
Published 2014-02-01

Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain.

by Sonja C Vernes, Peter L Oliver, Elizabeth Spiteri, Helen E Lockstone, Rathi Puliyadi, Jennifer M Taylor, Joses Ho, Cedric Mombereau, Ariel Brewer, Ernesto Lowy, Jérôme Nicod, Matthias Groszer, Dilair Baban, Natasha Sahgal, Jean-Baptiste Cazier, Jiannis Ragoussis, Kay E Davies, Daniel H Geschwind, Simon E Fisher
Published 2011-07-01