The Regulatory Status Adopted by Lymph Node Dendritic Cells and T Cells During Healthy Aging Is Maintained During Cancer and May Contribute to Reduced Responses to Immunotherapy

by Joanne K. Gardner, Joanne K. Gardner, Connie Jackaman, Connie Jackaman, Cyril D. S. Mamotte, Cyril D. S. Mamotte, Delia J. Nelson, Delia J. Nelson
Published 2018-11-01

Rapid copper acquisition by developing murine mesothelioma: decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltration.

by Andrew Crowe, Connie Jackaman, Katie M Beddoes, Belinda Ricciardo, Delia J Nelson
Published 2013-01-01

Mesothelioma tumor cells modulate dendritic cell lipid content, phenotype and function.

by Joanne K Gardner, Cyril D S Mamotte, Priya Patel, Teong Ling Yeoh, Connie Jackaman, Delia J Nelson
Published 2015-01-01

Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation.

by Joanne K Gardner, Scott M J Cornwall, Arthur W Musk, John Alvarez, Cyril D S Mamotte, Connie Jackaman, Anna K Nowak, Delia J Nelson
Published 2018-01-01

CD8+ cytotoxic T cell responses to dominant tumor-associated antigens are profoundly weakened by aging yet subdominant responses retain functionality and expand in response to chem...

by Connie Jackaman, Joanne K. Gardner, Federica Tomay, Joshua Spowart, Hannah Crabb, Danielle E. Dye, Simon Fox, Stephen Proksch, Pat Metharom, Satvinder S. Dhaliwal, Delia J. Nelson
Published 2019-04-01

Macrophage Depletion in Elderly Mice Improves Response to Tumor Immunotherapy, Increases Anti-tumor T Cell Activity and Reduces Treatment-Induced Cachexia

by Lelinh Duong, Hannah G. Radley-Crabb, Joanne K. Gardner, Federica Tomay, Danielle E. Dye, Miranda D. Grounds, Fiona J. Pixley, Delia J. Nelson, Connie Jackaman
Published 2018-11-01

Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression.

by Gianina Ravenscroft, Connie Jackaman, Caroline A Sewry, Elyshia McNamara, Sarah E Squire, Allyson C Potter, John Papadimitriou, Lisa M Griffiths, Anthony J Bakker, Kay E Davies, Nigel G Laing, Kristen J Nowak
Published 2011-01-01