Assessing Plasmodium falciparum transmission in mosquito-feeding assays using quantitative PCR

by Claire Y. T. Wang, James S. McCarthy, Will J. Stone, Teun Bousema, Katharine A. Collins, Seweryn Bialasiewicz
Published 2018-07-01

Assays for quantification of male and female gametocytes in human blood by qRT-PCR in the absence of pure sex-specific gametocyte standards

by Claire Y. T. Wang, Emma Ballard, Stacey Llewellyn, Louise Marquart, Teun Bousema, James S. McCarthy, Katharine A. Collins
Published 2020-06-01

A mosquito feeding assay to examine Plasmodium transmission to mosquitoes using small blood volumes in 3D printed nano-feeders

by Wouter Graumans, Roel Heutink, Geert-Jan van Gemert, Marga van de Vegte-Bolmer, Teun Bousema, Katharine A. Collins
Published 2020-08-01

A portfolio of geographically distinct laboratory-adapted Plasmodium falciparum clones with consistent infection rates in Anopheles mosquitoes

by Marga van de Vegte-Bolmer, Wouter Graumans, Rianne Stoter, Geert-Jan van Gemert, Robert Sauerwein, Katharine A. Collins, Teun Bousema
Published 2021-09-01

Modeling the dynamics of Plasmodium falciparum gametocytes in humans during malaria infection

by Pengxing Cao, Katharine A Collins, Sophie Zaloumis, Thanaporn Wattanakul, Joel Tarning, Julie A Simpson, James McCarthy, James M McCaw
Published 2019-10-01

Ultra-low dose immunization and multi-component vaccination strategies enhance protection against malaria in mice

by Katharine A. Collins, Florian Brod, Rebecca Snaith, Marta Ulaszewska, Rhea J. Longley, Ahmed M. Salman, Sarah C. Gilbert, Alexandra J. Spencer, David Franco, W. Ripley Ballou, Adrian V. S. Hill
Published 2021-05-01

A multiplex assay for the sensitive detection and quantification of male and female Plasmodium falciparum gametocytes

by Lisette Meerstein-Kessel, Chiara Andolina, Elvira Carrio, Almahamoudou Mahamar, Patrick Sawa, Halimatou Diawara, Marga van de Vegte-Bolmer, Will Stone, Katharine A. Collins, Petra Schneider, Alassane Dicko, Chris Drakeley, Ingrid Felger, Till Voss, Kjerstin Lanke, Teun Bousema
Published 2018-11-01

Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: A pilot and a randomised volunteer infection study in Australia.

by Rebecca E Watts, Anand Odedra, Louise Marquart, Lachlan Webb, Azrin N Abd-Rahman, Laura Cascales, Stephan Chalon, Maria Rebelo, Zuleima Pava, Katharine A Collins, Cielo Pasay, Nanhua Chen, Christopher L Peatey, Jörg J Möhrle, James S McCarthy
Published 2020-08-01

Safety and feasibility of apheresis to harvest and concentrate parasites from subjects with induced blood stage Plasmodium vivax infection

by Anand Odedra, Kari Mudie, Glen Kennedy, Rebecca E. Watts, Emilie Rossignol, Hayley Mitchell, Jeremy Gower, Maria Rebelo, Zuleima Pava, Rebecca Pawliw, Stephen Woolley, David G. Lalloo, Greg Robinson, Sean Lynch, Katharine A. Collins, Fiona Amante, James McCarthy
Published 2021-01-01

Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure.

by Sumi Biswas, Prateek Choudhary, Sean C Elias, Kazutoyo Miura, Kathryn H Milne, Simone C de Cassan, Katharine A Collins, Fenella D Halstead, Carly M Bliss, Katie J Ewer, Faith H Osier, Susanne H Hodgson, Christopher J A Duncan, Geraldine A O'Hara, Carole A Long, Adrian V S Hill, Simon J Draper
Published 2014-01-01

Maintaining Plasmodium falciparum gametocyte infectivity during blood collection and transport for mosquito feeding assays in the field

by Harouna M. Soumare, Wamdaogo Moussa Guelbeogo, Marga van de Vegte-Bolmer, Geert-Jan van Gemert, Zongo Soumanaba, Alphonse Ouedraogo, Maurice S. Ouattara, Ahmad Abdullahi, Lamin Jadama, Muhammed M. Camara, Pa Modou Gaye, Michael Mendy, Nwakanma Davis, Alfred B. Tiono, Umberto D’Alessandro, Chris Drakeley, Teun Bousema, Marta Moreno, Katharine A. Collins
Published 2021-04-01

A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection model

by Isaie J Reuling, Lisanne A van de Schans, Luc E Coffeng, Kjerstin Lanke, Lisette Meerstein-Kessel, Wouter Graumans, Geert-Jan van Gemert, Karina Teelen, Rianne Siebelink-Stoter, Marga van de Vegte-Bolmer, Quirijn de Mast, André J van der Ven, Karen Ivinson, Cornelus C Hermsen, Sake de Vlas, John Bradley, Katharine A Collins, Christian F Ockenhouse, James McCarthy, Robert W Sauerwein, Teun Bousema
Published 2018-02-01

Phase Ia clinical evaluation of the safety and immunogenicity of the Plasmodium falciparum blood-stage antigen AMA1 in ChAd63 and MVA vaccine vectors.

by Susanne H Sheehy, Christopher J A Duncan, Sean C Elias, Sumi Biswas, Katharine A Collins, Geraldine A O'Hara, Fenella D Halstead, Katie J Ewer, Tabitha Mahungu, Alexandra J Spencer, Kazutoyo Miura, Ian D Poulton, Matthew D J Dicks, Nick J Edwards, Eleanor Berrie, Sarah Moyle, Stefano Colloca, Riccardo Cortese, Katherine Gantlett, Carole A Long, Alison M Lawrie, Sarah C Gilbert, Tom Doherty, Alfredo Nicosia, Adrian V S Hill, Simon J Draper
Published 2012-01-01

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.

by Christopher J A Duncan, Susanne H Sheehy, Katie J Ewer, Alexander D Douglas, Katharine A Collins, Fenella D Halstead, Sean C Elias, Patrick J Lillie, Kelly Rausch, Joan Aebig, Kazutoyo Miura, Nick J Edwards, Ian D Poulton, Angela Hunt-Cooke, David W Porter, Fiona M Thompson, Ros Rowland, Simon J Draper, Sarah C Gilbert, Michael P Fay, Carole A Long, Daming Zhu, Yimin Wu, Laura B Martin, Charles F Anderson, Alison M Lawrie, Adrian V S Hill, Ruth D Ellis
Published 2011-01-01

Safety and immunogenicity of heterologous prime-boost immunisation with Plasmodium falciparum malaria candidate vaccines, ChAd63 ME-TRAP and MVA ME-TRAP, in healthy Gambian and Ken...

by Caroline Ogwang, Muhammed Afolabi, Domtila Kimani, Ya Jankey Jagne, Susanne H Sheehy, Carly M Bliss, Christopher J A Duncan, Katharine A Collins, Miguel A Garcia Knight, Eva Kimani, Nicholas A Anagnostou, Eleanor Berrie, Sarah Moyle, Sarah C Gilbert, Alexandra J Spencer, Peninah Soipei, Jenny Mueller, Joseph Okebe, Stefano Colloca, Riccardo Cortese, Nicola K Viebig, Rachel Roberts, Katherine Gantlett, Alison M Lawrie, Alfredo Nicosia, Egeruan B Imoukhuede, Philip Bejon, Britta C Urban, Katie L Flanagan, Katie J Ewer, Roma Chilengi, Adrian V S Hill, Kalifa Bojang
Published 2013-01-01