Microarray analysis of CA1 pyramidal neurons in a mouse model of tauopathy reveals progressive synaptic dysfunction

by Melissa J. Alldred, Karen E. Duff, Stephen D. Ginsberg
Published 2012-02-01

Chemogenetic attenuation of neuronal activity in the entorhinal cortex reduces Aβ and tau pathology in the hippocampus.

by Gustavo A Rodriguez, Geoffrey M Barrett, Karen E Duff, S Abid Hussaini
Published 2020-08-01

The Endosomal–Lysosomal Pathway Is Dysregulated by APOE4 Expression in Vivo

by Tal Nuriel, Katherine Y. Peng, Archana Ashok, Allissa A. Dillman, Allissa A. Dillman, Helen Y. Figueroa, Justin Apuzzo, Jayanth Ambat, Efrat Levy, Efrat Levy, Efrat Levy, Efrat Levy, Mark R. Cookson, Paul M. Mathews, Paul M. Mathews, Karen E. Duff, Karen E. Duff
Published 2017-12-01

3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Age...

by Hongjun Fu, S Abid Hussaini, Susanne Wegmann, Caterina Profaci, Jacob D Daniels, Mathieu Herman, Sheina Emrani, Helen Y Figueroa, Bradley T Hyman, Peter Davies, Karen E Duff
Published 2016-01-01

Evidence for peripheral clearance of cerebral Aβ protein following chronic, active Aβ immunization in PSAPP mice

by Cynthia A Lemere, Edward T Spooner, John LaFrancois, Brian Malester, Chica Mori, Jodi F Leverone, Yasuji Matsuoka, Jennie W Taylor, Ronald B DeMattos, David M Holtzman, John D Clements, Dennis J Selkoe, Karen E Duff
Published 2003-10-01

Neuronal hyperactivity due to loss of inhibitory tone in APOE4 mice lacking Alzheimer’s disease-like pathology

by Tal Nuriel, Sergio L. Angulo, Usman Khan, Archana Ashok, Qiuying Chen, Helen Y. Figueroa, Sheina Emrani, Li Liu, Mathieu Herman, Geoffrey Barrett, Valerie Savage, Luna Buitrago, Efrain Cepeda-Prado, Christine Fung, Eliana Goldberg, Steven S. Gross, S. Abid Hussaini, Herman Moreno, Scott A. Small, Karen E. Duff
Published 2017-11-01