Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV.

by Jonathan K Chan, Darshana Bhattacharyya, Kara G Lassen, Debbie Ruelas, Warner C Greene
Published 2013-01-01

A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs.

by Kara G Lassen, Andrew M Hebbeler, Darshana Bhattacharyya, Michael A Lobritz, Warner C Greene
Published 2012-01-01

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells.

by Kara G Lassen, Kasra X Ramyar, Justin R Bailey, Yan Zhou, Robert F Siliciano
Published 2006-07-01

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.

by Ianina C Ferder, Leslie Fung, Yasuyo Ohguchi, Xiaoyu Zhang, Kara G Lassen, Diane Capen, Dennis Brown, Ramnik J Xavier, Ning Wang
Published 2019-05-01

Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1).

by Naoki Sakane, Hye-Sook Kwon, Sara Pagans, Katrin Kaehlcke, Yasuhiro Mizusawa, Masafumi Kamada, Kara G Lassen, Jonathan Chan, Warner C Greene, Martina Schnoelzer, Melanie Ott
Published 2011-08-01

An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouse.

by Juan Liao, Humberto B Jijon, Ira R Kim, Gautam Goel, Aivi Doan, Harry Sokol, Hermann Bauer, Bernhard G Herrmann, Kara G Lassen, Ramnik J Xavier
Published 2014-01-01

Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics.

by Kara G Lassen, Michael A Lobritz, Justin R Bailey, Samantha Johnston, Sandra Nguyen, Benhur Lee, Tom Chou, Robert F Siliciano, Martin Markowitz, Eric J Arts
Published 2009-04-01

The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

by Sydney Lavoie, Kara L Conway, Kara G Lassen, Humberto B Jijon, Hui Pan, Eunyoung Chun, Monia Michaud, Jessica K Lang, Carey Ann Gallini Comeau, Jonathan M Dreyfuss, Jonathan N Glickman, Hera Vlamakis, Ashwin Ananthakrishnan, Aleksander Kostic, Wendy S Garrett, Ramnik J Xavier
Published 2019-01-01

Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

by Jakob Begun, Kara G. Lassen, Humberto B. Jijon, Leigh A. Baxt, Gautam Goel, Robert J. Heath, Aylwin Ng, Jenny M. Tam, Szu-Yu Kuo, Eduardo J. Villablanca, Lola Fagbami, Marije Oosting, Vinod Kumar, Monica Schenone, Steven A. Carr, Leo A.B. Joosten, Jatin M. Vyas, Mark J. Daly, Mihai G. Netea, Gordon D. Brown, Cisca Wijmenga, Ramnik J. Xavier
Published 2015-06-01