Diagnosing tuberculosis in the 21st century – Dawn of a genomics revolution?

by Christopher Jeanes, Justin O'Grady
Published 2016-01-01

Co-infections: potentially lethal and unexplored in COVID-19

by Michael J Cox, Nicholas Loman, Debby Bogaert, Justin O'Grady
Published 2020-05-01

Application of highly portable MinION nanopore sequencing technology for the monitoring of nosocomial tuberculosis infection

by Matthew Bates, Pascal Polepole, Nathan Kapata, Matt Loose, Justin O′Grady
Published 2016-01-01

Tuberculosis trends in Saudis and non-Saudis in the Kingdom of Saudi Arabia--a 10 year retrospective study (2000-2009).

by Mohammad S Abouzeid, Alimuddin I Zumla, Shaza Felemban, Badriah Alotaibi, Justin O'Grady, Ziad A Memish
Published 2012-01-01

A novel multiplex real-time PCR for the identification of mycobacteria associated with zoonotic tuberculosis.

by Kate Reddington, Justin O'Grady, Siobhan Dorai-Raj, Stefan Niemann, Dick van Soolingen, Thomas Barry
Published 2011-01-01

Performance of the Xpert MTB/RIF assay in the diagnosis of tuberculosis in formalin-fixed, paraffin-embedded tissues

by Pascal Polepole, Mwila Kabwe, Mpanga Kasonde, John Tembo, Aaron Shibemba, Justin O'Grady, Nathan Kapata, Alimuddin Zumla, Matthew Bates
Published 2017-01-01

An optimised protocol for detection of SARS-CoV-2 in stool

by Tianqi Li, Enriqueta Garcia-Gutierrez, Daniel A. Yara, Jacob Scadden, Jade Davies, Chloe Hutchins, Alp Aydin, Justin O’Grady, Arjan Narbad, Stefano Romano, Lizbeth Sayavedra
Published 2021-09-01

Leprosy at the edge of Europe-Biomolecular, isotopic and osteoarchaeological findings from medieval Ireland.

by G Michael Taylor, Eileen M Murphy, Tom A Mendum, Alistair W G Pike, Bethan Linscott, Huihai Wu, Justin O'Grady, Hollian Richardson, Edmond O'Donovan, Carmelita Troy, Graham R Stewart
Published 2018-01-01

Rapid and accurate detection of Mycobacterium tuberculosis in sputum samples by Cepheid Xpert MTB/RIF assay--a clinical validation study.

by Andrea Rachow, Alimuddin Zumla, Norbert Heinrich, Gabriel Rojas-Ponce, Bariki Mtafya, Klaus Reither, Elias N Ntinginya, Justin O'Grady, Jim Huggett, Keertan Dheda, Catharina Boehme, Mark Perkins, Elmar Saathoff, Michael Hoelscher
Published 2011-01-01

Integrating informatics tools and portable sequencing technology for rapid detection of resistance to anti-tuberculous drugs

by Jody E. Phelan, Denise M. O’Sullivan, Diana Machado, Jorge Ramos, Yaa E. A. Oppong, Susana Campino, Justin O’Grady, Ruth McNerney, Martin L. Hibberd, Miguel Viveiros, Jim F. Huggett, Taane G. Clark
Published 2019-06-01

Surveillance of SARS-CoV-2 in Zimbabwe shows dominance of variants of concern

by Tapfumanei Mashe, Faustinos Tatenda Takawira, Hlanai Gumbo, Agnes Juru, Charles Nyagupe, Kenneth K Maeka, Sekesai Mtapuri-Zinyowera, Muchaneta Gudza-Mugabe, Leonardo de Oliveira Martins, Justin O'Grady, Robert A Kingsley, Andrew J Page, Raiva Simbi
Published 2021-05-01

Evaluation of the burden of unsuspected pulmonary tuberculosis and co-morbidity with non-communicable diseases in sputum producing adult inpatients.

by Matthew Bates, Justin O'Grady, Peter Mwaba, Lophina Chilukutu, Judith Mzyece, Busiku Cheelo, Moses Chilufya, Lukundo Mukonda, Maxwell Mumba, John Tembo, Mumba Chomba, Nathan Kapata, Andrea Rachow, Petra Clowes, Markus Maeurer, Michael Hoelscher, Alimuddin Zumla
Published 2012-01-01

Metagenomic identification of severe pneumonia pathogens in mechanically-ventilated patients: a feasibility and clinical validity study

by Libing Yang, Ghady Haidar, Haris Zia, Rachel Nettles, Shulin Qin, Xiaohong Wang, Faraaz Shah, Sarah F. Rapport, Themoula Charalampous, Barbara Methé, Adam Fitch, Alison Morris, Bryan J. McVerry, Justin O’Grady, Georgios D. Kitsios
Published 2019-11-01

INHALE: the impact of using FilmArray Pneumonia Panel molecular diagnostics for hospital-acquired and ventilator-associated pneumonia on antimicrobial stewardship and patient outco...

by Juliet High, Virve I. Enne, Julie A. Barber, David Brealey, David A. Turner, Robert Horne, Mark Peters, Zaneeta Dhesi, Adam P. Wagner, Alyssa M. Pandolfo, Sue Stirling, Charlotte Russell, Justin O’Grady, Ann Marie Swart, Vanya Gant, David M. Livermore, INHALE Study Group
Published 2021-10-01

MinION Analysis and Reference Consortium: Phase 2 data release and analysis of R9.0 chemistry [version 1; referees: 1 approved, 2 approved with reservations]

by Miten Jain, John R. Tyson, Matthew Loose, Camilla L.C. Ip, David A. Eccles, Justin O'Grady, Sunir Malla, Richard M. Leggett, Ola Wallerman, Hans J. Jansen, Vadim Zalunin, Ewan Birney, Bonnie L. Brown, Terrance P. Snutch, Hugh E. Olsen, MinION Analysis and Reference Consortium
Published 2017-05-01

The challenges of designing a benchmark strategy for bioinformatics pipelines in the identification of antimicrobial resistance determinants using next generation sequencing techno...

by Alexandre Angers-Loustau, Mauro Petrillo, Johan Bengtsson-Palme, Thomas Berendonk, Burton Blais, Kok-Gan Chan, Teresa M. Coque, Paul Hammer, Stefanie Heß, Dafni M. Kagkli, Carsten Krumbiegel, Val F. Lanza, Jean-Yves Madec, Thierry Naas, Justin O'Grady, Valentina Paracchini, John W.A. Rossen, Etienne Ruppé, Jessica Vamathevan, Vittorio Venturi, Guy Van den Eede
Published 2018-04-01

The challenges of designing a benchmark strategy for bioinformatics pipelines in the identification of antimicrobial resistance determinants using next generation sequencing techno...

by Alexandre Angers-Loustau, Mauro Petrillo, Johan Bengtsson-Palme, Thomas Berendonk, Burton Blais, Kok-Gan Chan, Teresa M. Coque, Paul Hammer, Stefanie Heß, Dafni M. Kagkli, Carsten Krumbiegel, Val F. Lanza, Jean-Yves Madec, Thierry Naas, Justin O'Grady, Valentina Paracchini, John W.A. Rossen, Etienne Ruppé, Jessica Vamathevan, Vittorio Venturi, Guy Van den Eede
Published 2018-12-01

MinION Analysis and Reference Consortium: Phase 1 data release and analysis [version 1; referees: 2 approved]

by Camilla L.C. Ip, Matthew Loose, John R. Tyson, Mariateresa de Cesare, Bonnie L. Brown, Miten Jain, Richard M. Leggett, David A. Eccles, Vadim Zalunin, John M. Urban, Paolo Piazza, Rory J. Bowden, Benedict Paten, Solomon Mwaigwisya, Elizabeth M. Batty, Jared T. Simpson, Terrance P. Snutch, Ewan Birney, David Buck, Sara Goodwin, Hans J. Jansen, Justin O'Grady, Hugh E. Olsen, MinION Analysis and Reference Consortium
Published 2015-10-01

CoronaHiT: high-throughput sequencing of SARS-CoV-2 genomes

by Dave J. Baker, Alp Aydin, Thanh Le-Viet, Gemma L. Kay, Steven Rudder, Leonardo de Oliveira Martins, Ana P. Tedim, Anastasia Kolyva, Maria Diaz, Nabil-Fareed Alikhan, Lizzie Meadows, Andrew Bell, Ana Victoria Gutierrez, Alexander J. Trotter, Nicholas M. Thomson, Rachel Gilroy, Luke Griffith, Evelien M. Adriaenssens, Rachael Stanley, Ian G. Charles, Ngozi Elumogo, John Wain, Reenesh Prakash, Emma Meader, Alison E. Mather, Mark A. Webber, Samir Dervisevic, Andrew J. Page, Justin O’Grady
Published 2021-02-01

An inter-laboratory study to investigate the impact of the bioinformatics component on microbiome analysis using mock communities

by Denise M. O’Sullivan, Ronan M. Doyle, Sasithon Temisak, Nicholas Redshaw, Alexandra S. Whale, Grace Logan, Jiabin Huang, Nicole Fischer, Gregory C. A. Amos, Mark D. Preston, Julian R. Marchesi, Josef Wagner, Julian Parkhill, Yair Motro, Hubert Denise, Robert D. Finn, Kathryn A. Harris, Gemma L. Kay, Justin O’Grady, Emma Ransom-Jones, Huihai Wu, Emma Laing, David J. Studholme, Ernest Diez Benavente, Jody Phelan, Taane G. Clark, Jacob Moran-Gilad, Jim F. Huggett
Published 2021-05-01