Addressing the selectivity and toxicity of antiviral nucleosides

by Joy Y Feng
Published 2018-03-01

Mechanism of Inhibition of Ebola Virus RNA-Dependent RNA Polymerase by Remdesivir

by Egor P. Tchesnokov, Joy Y. Feng, Danielle P. Porter, Matthias Götte
Published 2019-04-01

Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Polymerase activity and mechanisms of action of nucleotide analogs.

by Ona Barauskas, Weimei Xing, Esmeralda Aguayo, Madeleine Willkom, Annapurna Sapre, Michael Clarke, Gabriel Birkus, Brian E Schultz, Roman Sakowicz, HyockJoo Kwon, Joy Y Feng
Published 2017-01-01

Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors.

by Weimei Xing, Ona Barauskas, Thorsten Kirschberg, Anita Niedziela-Majka, Michael Clarke, Gabriel Birkus, Perry Weissburg, Xiaohong Liu, Brian E Schultz, Roman Sakowicz, HyockJoo Kwon, Joy Y Feng
Published 2017-01-01

Prevention and therapy of SARS-CoV-2 and the B.1.351 variant in mice

by David R. Martinez, Alexandra Schäfer, Sarah R. Leist, Dapeng Li, Kendra Gully, Boyd Yount, Joy Y. Feng, Elaine Bunyan, Danielle P. Porter, Tomas Cihlar, Stephanie A. Montgomery, Barton F. Haynes, Ralph S. Baric, Michel C. Nussenzweig, Timothy P. Sheahan
Published 2021-07-01

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

by Maria L. Agostini, Erica L. Andres, Amy C. Sims, Rachel L. Graham, Timothy P. Sheahan, Xiaotao Lu, Everett Clinton Smith, James Brett Case, Joy Y. Feng, Robert Jordan, Adrian S. Ray, Tomas Cihlar, Dustin Siegel, Richard L. Mackman, Michael O. Clarke, Ralph S. Baric, Mark R. Denison, Kanta Subbarao
Published 2018-03-01

Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV

by Timothy P. Sheahan, Amy C. Sims, Sarah R. Leist, Alexandra Schäfer, John Won, Ariane J. Brown, Stephanie A. Montgomery, Alison Hogg, Darius Babusis, Michael O. Clarke, Jamie E. Spahn, Laura Bauer, Scott Sellers, Danielle Porter, Joy Y. Feng, Tomas Cihlar, Robert Jordan, Mark R. Denison, Ralph S. Baric
Published 2020-01-01

Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides.

by Jamie J Arnold, Suresh D Sharma, Joy Y Feng, Adrian S Ray, Eric D Smidansky, Maria L Kireeva, Aesop Cho, Jason Perry, Jennifer E Vela, Yeojin Park, Yili Xu, Yang Tian, Darius Babusis, Ona Barauskus, Blake R Peterson, Averell Gnatt, Mikhail Kashlev, Weidong Zhong, Craig E Cameron
Published 2012-01-01