IDO and Kynurenine Metabolites in Peripheral and CNS Disorders

by Yi-Shu Huang, Joy Ogbechi, Felix I. Clanchy, Richard O. Williams, Trevor W. Stone
Published 2020-03-01

The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER.

by Belinda S Hall, Kirsti Hill, Michael McKenna, Joy Ogbechi, Stephen High, Anne E Willis, Rachel E Simmonds
Published 2014-04-01

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions.

by Joy Ogbechi, Marie-Thérèse Ruf, Belinda S Hall, Katherine Bodman-Smith, Moritz Vogel, Hua-Lin Wu, Alexander Stainer, Charles T Esmon, Josefin Ahnström, Gerd Pluschke, Rachel E Simmonds
Published 2015-07-01