Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor

by Karyn Schmidt, Chase A. Weidmann, Thomas A. Hilimire, Elaine Yee, Breanne M. Hatfield, John S. Schneekloth, Jr., Kevin M. Weeks, Carl D. Novina
Published 2020-01-01

A chemical probe based on the PreQ1 metabolite enables transcriptome-wide mapping of binding sites

by Sumirtha Balaratnam, Curran Rhodes, Desta Doro Bume, Colleen Connelly, Christopher C. Lai, James A. Kelley, Kamyar Yazdani, Philip J. Homan, Danny Incarnato, Tomoyuki Numata, John S. Schneekloth Jr
Published 2021-10-01

A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

by Miyuki Suzawa, Diego A Miranda, Karmela A Ramos, Kenny K-H Ang, Emily J Faivre, Christopher G Wilson, Laura Caboni, Michelle R Arkin, Yeong-Sang Kim, Robert J Fletterick, Aaron Diaz, John S Schneekloth Jr, Holly A Ingraham
Published 2015-12-01