The herbicide atrazine activates endocrine gene networks via non-steroidal NR5A nuclear receptors in fish and mammalian cells.

by Miyuki Suzawa, Holly A Ingraham
Published 2008-01-01

Sex-dependent changes in metabolism and behavior, as well as reduced anxiety after eliminating ventromedial hypothalamus excitatory output

by Clement C. Cheung, William C. Krause, Robert H. Edwards, Cindy F. Yang, Nirao M. Shah, Thomas S. Hnasko, Holly A. Ingraham
Published 2015-11-01

LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival

by James R. Bayrer, Hongtao Wang, Roy Nattiv, Miyuki Suzawa, Hazel S. Escusa, Robert J. Fletterick, Ophir D. Klein, David D. Moore, Holly A. Ingraham
Published 2018-10-01

Disulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2).

by Felipe de Jesus Cortez, Miyuki Suzawa, Sam Irvy, John M Bruning, Elena Sablin, Matthew P Jacobson, Robert J Fletterick, Holly A Ingraham, Pamela M England
Published 2016-01-01

An Estrogen-Responsive Module in the Ventromedial Hypothalamus Selectively Drives Sex-Specific Activity in Females

by Stephanie M. Correa, David W. Newstrom, James P. Warne, Pierre Flandin, Clement C. Cheung, Alexander T. Lin-Moore, Andrew A. Pierce, Allison W. Xu, John L. Rubenstein, Holly A. Ingraham
Published 2015-01-01

Estrogen signaling in arcuate Kiss1 neurons suppresses a sex-dependent female circuit promoting dense strong bones

by Candice B. Herber, William C. Krause, Liping Wang, James R. Bayrer, Alfred Li, Matthew Schmitz, Aaron Fields, Breanna Ford, Zhi Zhang, Michelle S. Reid, Daniel K. Nomura, Robert A. Nissenson, Stephanie M. Correa, Holly A. Ingraham
Published 2019-01-01

A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver

by Miyuki Suzawa, Diego A Miranda, Karmela A Ramos, Kenny K-H Ang, Emily J Faivre, Christopher G Wilson, Laura Caboni, Michelle R Arkin, Yeong-Sang Kim, Robert J Fletterick, Aaron Diaz, John S Schneekloth Jr, Holly A Ingraham
Published 2015-12-01