Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics.

by Johnson Agniswamy, John M Louis, Julien Roche, Robert W Harrison, Irene T Weber
Published 2016-01-01

Fast three-color single-molecule FRET using statistical inference

by Janghyun Yoo, Jae-Yeol Kim, John M. Louis, Irina V. Gopich, Hoi Sung Chung
Published 2020-07-01

Insights into the Conformation of the Membrane Proximal Regions Critical to the Trimerization of the HIV-1 gp41 Ectodomain Bound to Dodecyl Phosphocholine Micelles.

by John M Louis, James L Baber, Rodolfo Ghirlando, Annie Aniana, Ad Bax, Julien Roche
Published 2016-01-01

Binding of HIV-1 gp41-directed neutralizing and non-neutralizing fragment antibody binding domain (Fab) and single chain variable fragment (ScFv) antibodies to the ectodomain of gp...

by John M Louis, Annie Aniana, Katheryn Lohith, Jane M Sayer, Julien Roche, Carole A Bewley, G Marius Clore
Published 2014-01-01

Structural basis of HIV-1 neutralization by affinity matured Fabs directed against the internal trimeric coiled-coil of gp41.

by Elena Gustchina, Mi Li, John M Louis, D Eric Anderson, John Lloyd, Christian Frisch, Carole A Bewley, Alla Gustchina, Alexander Wlodawer, G Marius Clore
Published 2010-11-01

Complexes of neutralizing and non-neutralizing affinity matured Fabs with a mimetic of the internal trimeric coiled-coil of HIV-1 gp41.

by Elena Gustchina, Mi Li, Rodolfo Ghirlando, Peter Schuck, John M Louis, Jason Pierson, Prashant Rao, Sriram Subramaniam, Alla Gustchina, G Marius Clore, Alexander Wlodawer
Published 2013-01-01