MECHANISMS OF RESISTANCE TO ANTIPARASITIC DRUGS IN TRYPANOSOMA CRUZI. CORRELATIONS BETWEEN GENOTYPE AND RESISTANCE

by John M Kelly, Shane R. Wilkinson
Published 2013-01-01

Non-invasive monitoring of drug action: A new live in vitro assay design for Chagas' disease drug discovery.

by Anna F Fesser, Olivier Braissant, Francisco Olmo, John M Kelly, Pascal Mäser, Marcel Kaiser
Published 2020-07-01

Trypanosoma cruzi amastigotes that persist in the colon during chronic stage murine infections have a reduced replication rate

by Alexander I. Ward, Francisco Olmo, Richard L. Atherton, Martin C. Taylor, John M. Kelly
Published 2020-12-01

Highly Sensitive Bioluminescence Imaging Models for Chagas Disease Drug Discovery

by John M. Kelly, Amanda F. Francisco, Shiromani Jayawardhana, Martin C. Taylor, Michael D. Lewis
Published 2017-10-01

The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence.

by Martin C Taylor, Michael D Lewis, Amanda Fortes Francisco, Shane R Wilkinson, John M Kelly
Published 2015-04-01

Imaging the development of chronic Chagas disease after oral transmission

by Michael D. Lewis, Amanda F. Francisco, Shiromani Jayawardhana, Harry Langston, Martin C. Taylor, John M. Kelly
Published 2018-07-01

Image-Based In Vitro Screening Reveals the Trypanostatic Activity of Hydroxymethylnitrofurazone against <i>Trypanosoma cruzi</i>

by Cauê Benito Scarim, Francisco Olmo, Elizabeth Igne Ferreira, Chung Man Chin, John M. Kelly, Amanda Fortes Francisco
Published 2021-06-01

Intracellular DNA replication and differentiation of Trypanosoma cruzi is asynchronous within individual host cells in vivo at all stages of infection.

by Martin C Taylor, Alexander Ward, Francisco Olmo, Shiromani Jayawardhana, Amanda F Francisco, Michael D Lewis, John M Kelly
Published 2020-03-01

Challenges in Chagas Disease Drug Development

by Amanda F. Francisco, Shiromani Jayawardhana, Francisco Olmo, Michael D. Lewis, Shane R. Wilkinson, Martin C. Taylor, John M. Kelly
Published 2020-06-01

Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA

by Andrea Bistrović, Luka Krstulović, Ivana Stolić, Domagoj Drenjančević, Jasminka Talapko, Martin C. Taylor, John M. Kelly, Miroslav Bajić, Silvana Raić-Malić
Published 2018-01-01

Tetrasubstituted Imidazolium Salts as Potent Antiparasitic Agents against African and American Trypanosomiases

by Ouldouz Ghashghaei, Nicola Kielland, Marc Revés, Martin C. Taylor, John M. Kelly, Ornella Di Pietro, Diego Muñoz-Torrero, Belén Pérez, Rodolfo Lavilla
Published 2018-01-01

Synthesis, antiproliferative and antitrypanosomal activities, and DNA binding of novel 6-amidino-2-arylbenzothiazoles

by Livio Racané, Valentina Rep, Sandra Kraljević Pavelić, Petra Grbčić, Iva Zonjić, Marijana Radić Stojković, Martin C. Taylor, John M. Kelly, Silvana Raić-Malić
Published 2021-01-01

In Vivo Analysis of Trypanosoma cruzi Persistence Foci at Single-Cell Resolution

by Alexander I. Ward, Michael D. Lewis, Archie A. Khan, Conor J. McCann, Amanda F. Francisco, Shiromani Jayawardhana, Martin C. Taylor, John M. Kelly
Published 2020-08-01

Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase.

by Alex P McLatchie, Hollie Burrell-Saward, Elmarie Myburgh, Michael D Lewis, Theresa H Ward, Jeremy C Mottram, Simon L Croft, John M Kelly, Martin C Taylor
Published 2013-11-01

Drug-cured experimental Trypanosoma cruzi infections confer long-lasting and cross-strain protection.

by Gurdip Singh Mann, Amanda F Francisco, Shiromani Jayawardhana, Martin C Taylor, Michael D Lewis, Francisco Olmo, Elisangela Oliveira de Freitas, Fabiana M S Leoratti, Cesar López-Camacho, Arturo Reyes-Sandoval, John M Kelly
Published 2020-04-01

Publisher Correction: Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients

by Erica L. Schwarz, John M. Kelly, Kevin M. Blum, Kan N. Hor, Andrew R. Yates, Jacob C. Zbinden, Aekaansh Verma, Stephanie E. Lindsey, Abhay B. Ramachandra, Jason M. Szafron, Jay D. Humphrey, Toshiharu Shin’oka, Alison L. Marsden, Christopher K. Breuer
Published 2021-08-01

Hemodynamic performance of tissue-engineered vascular grafts in Fontan patients

by Erica L. Schwarz, John M. Kelly, Kevin M. Blum, Kan N. Hor, Andrew R. Yates, Jacob C. Zbinden, Aekaansh Verma, Stephanie E. Lindsey, Abhay B. Ramachandra, Jason M. Szafron, Jay D. Humphrey, Toshiharu Shin’oka, Alison L. Marsden, Christopher K. Breuer
Published 2021-07-01