EDEM2 and OS-9 are required for ER-associated degradation of non-glycosylated sonic hedgehog.

by Hsiang-Yun Tang, Chih-Hsiang Huang, Ya-Han Zhuang, John C Christianson, Xin Chen
Published 2014-01-01

Centrosomal localisation of the cancer/testis (CT) antigens NY-ESO-1 and MAGE-C1 is regulated by proteasome activity in tumour cells.

by Anna Pagotto, Otavia L Caballero, Norbert Volkmar, Sylvie Devalle, Andrew J G Simpson, Xin Lu, John C Christianson
Published 2013-01-01

Inadequate BiP availability defines endoplasmic reticulum stress

by Milena Vitale, Anush Bakunts, Andrea Orsi, Federica Lari, Laura Tadè, Alberto Danieli, Claudia Rato, Caterina Valetti, Roberto Sitia, Andrea Raimondi, John C Christianson, Eelco van Anken
Published 2019-03-01

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

by Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson
Published 2020-07-01

The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K

by Simon R. Bushell, Ashley C. W. Pike, Maria E. Falzone, Nils J. G. Rorsman, Chau M. Ta, Robin A. Corey, Thomas D. Newport, John C. Christianson, Lara F. Scofano, Chitra A. Shintre, Annamaria Tessitore, Amy Chu, Qinrui Wang, Leela Shrestha, Shubhashish M. M. Mukhopadhyay, James D. Love, Nicola A. Burgess-Brown, Rebecca Sitsapesan, Phillip J. Stansfeld, Juha T. Huiskonen, Paolo Tammaro, Alessio Accardi, Elisabeth P. Carpenter
Published 2019-09-01