Post‐GWAS Polygenic Risk Score: Utility and Challenges

by Tuan V Nguyen, John A Eisman
Published 2020-11-01

A profiling analysis of contributions of cigarette smoking, dietary calcium intakes, and physical activity to fragility fracture in the elderly

by Thuy T. Pham, Diep N. Nguyen, Eryk Dutkiewicz, Jacqueline R. Center, John A. Eisman, Tuan V. Nguyen
Published 2018-07-01

Vitamin D metabolites are lower with active Crohn’s disease and spontaneously recover with development of remission

by Craig Haifer, Ian C. Lawrance, Jacqueline R. Center, Michael W. Clarke, Prue H. Hart, John A. Eisman, Robyn Lucas, Simon Ghaly
Published 2019-07-01

Epidemiological transition to mortality and refracture following an initial fracture

by Thao Phuong Ho-Le, Thach S Tran, Dana Bliuc, Hanh M Pham, Steven A Frost, Jacqueline R Center, John A Eisman, Tuan V Nguyen
Published 2021-02-01

Establishing baseline absolute risk of subsequent fracture among adults presenting to hospital with a minimal-trauma-fracture

by Steven A. Frost, Ayano Kelly, Julia Gaudin, Lynette Mc Evoy, Carol Wilson, Lynda Marov, Carlos El Haddad, Jacqueline Center, John A. Eisman, Tuan V. Nguyen, Geraldine Hassett
Published 2020-02-01

External validation of the Garvan nomograms for predicting absolute fracture risk: the Tromsø study.

by Luai A Ahmed, Nguyen D Nguyen, Åshild Bjørnerem, Ragnar M Joakimsen, Lone Jørgensen, Jan Størmer, Dana Bliuc, Jacqueline R Center, John A Eisman, Tuan V Nguyen, Nina Emaus
Published 2014-01-01

Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology.

by Iris P L Wong, Frank Driessler, Ee Cheng Khor, Yan-Chuan Shi, Birgit Hörmer, Amy D Nguyen, Ronaldo F Enriquez, John A Eisman, Amanda Sainsbury, Herbert Herzog, Paul A Baldock
Published 2012-01-01

Severe Hypertriglyceridemia Associated With Everolimus Treatment After Heart Transplantation

by Phillip Lo, MD, MMed, Katherine Kearney, MBBS, MMed, FRACP, Christopher A. Muir, MBBS, FRACP, Ning Song, MBBS, FRACP, John A. Eisman, MBBS, PhD, FRACP, Peter S. Macdonald, MBBS, MD, PhD, FRACP
Published 2020-09-01

Reduced mortality and subsequent fracture risk associated with oral bisphosphonate recommendation in a fracture liaison service setting: A prospective cohort study.

by Tineke A C M van Geel, Dana Bliuc, Piet P M Geusens, Jacqueline R Center, Geert-Jan Dinant, Thach Tran, Joop P W van den Bergh, Alastair R McLellan, John A Eisman
Published 2018-01-01

Neuropeptide Y knockout mice reveal a central role of NPY in the coordination of bone mass to body weight.

by Paul A Baldock, Nicola J Lee, Frank Driessler, Shu Lin, Susan Allison, Bernhard Stehrer, En-Ju D Lin, Lei Zhang, Ronald F Enriquez, Iris P L Wong, Michelle M McDonald, Matthew During, Dominique D Pierroz, Katy Slack, Yan C Shi, Ernie Yulyaningsih, Aygul Aljanova, David G Little, Serge L Ferrari, Amanda Sainsbury, John A Eisman, Herbert Herzog
Published 2009-01-01

Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

by Unnur Styrkarsdottir, Gudmar Thorleifsson, Sigurjon A. Gudjonsson, Asgeir Sigurdsson, Jacqueline R. Center, Seung Hun Lee, Tuan V. Nguyen, Timothy C.Y. Kwok, Jenny S.W. Lee, Suzanne C. Ho, Jean Woo, Ping-C. Leung, Beom-Jun Kim, Thorunn Rafnar, Lambertus A. Kiemeney, Thorvaldur Ingvarsson, Jung-Min Koh, Nelson L.S. Tang, John A. Eisman, Claus Christiansen, Gunnar Sigurdsson, Unnur Thorsteinsdottir, Kari Stefansson
Published 2016-01-01

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

by Scott E. Youlten, John P. Kemp, John G. Logan, Elena J. Ghirardello, Claudio M. Sergio, Michael R. G. Dack, Siobhan E. Guilfoyle, Victoria D. Leitch, Natalie C. Butterfield, Davide Komla-Ebri, Ryan C. Chai, Alexander P. Corr, James T. Smith, Sindhu T. Mohanty, John A. Morris, Michelle M. McDonald, Julian M. W. Quinn, Amelia R. McGlade, Nenad Bartonicek, Matt Jansson, Konstantinos Hatzikotoulas, Melita D. Irving, Ana Beleza-Meireles, Fernando Rivadeneira, Emma Duncan, J. Brent Richards, David J. Adams, Christopher J. Lelliott, Robert Brink, Tri Giang Phan, John A. Eisman, David M. Evans, Eleftheria Zeggini, Paul A. Baldock, J. H. Duncan Bassett, Graham R. Williams, Peter I. Croucher
Published 2021-05-01

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk.

by Emma L Duncan, Patrick Danoy, John P Kemp, Paul J Leo, Eugene McCloskey, Geoffrey C Nicholson, Richard Eastell, Richard L Prince, John A Eisman, Graeme Jones, Philip N Sambrook, Ian R Reid, Elaine M Dennison, John Wark, J Brent Richards, Andre G Uitterlinden, Tim D Spector, Chris Esapa, Roger D Cox, Steve D M Brown, Rajesh V Thakker, Kathryn A Addison, Linda A Bradbury, Jacqueline R Center, Cyrus Cooper, Catherine Cremin, Karol Estrada, Dieter Felsenberg, Claus-C Glüer, Johanna Hadler, Margaret J Henry, Albert Hofman, Mark A Kotowicz, Joanna Makovey, Sing C Nguyen, Tuan V Nguyen, Julie A Pasco, Karena Pryce, David M Reid, Fernando Rivadeneira, Christian Roux, Kari Stefansson, Unnur Styrkarsdottir, Gudmar Thorleifsson, Rumbidzai Tichawangana, David M Evans, Matthew A Brown
Published 2011-04-01

Publisher Correction: GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

by Unnur Styrkarsdottir, Olafur A. Stefansson, Kristbjorg Gunnarsdottir, Gudmar Thorleifsson, Sigrun H. Lund, Lilja Stefansdottir, Kristinn Juliusson, Arna B. Agustsdottir, Florian Zink, Gisli H. Halldorsson, Erna V. Ivarsdottir, Stefania Benonisdottir, Hakon Jonsson, Arnaldur Gylfason, Kristjan Norland, Katerina Trajanoska, Cindy G. Boer, Lorraine Southam, Jason C. S. Leung, Nelson L. S. Tang, Timothy C. Y. Kwok, Jenny S. W. Lee, Suzanne C. Ho, Inger Byrjalsen, Jacqueline R. Center, Seung Hun Lee, Jung-Min Koh, L. Stefan Lohmander, Lan T. Ho-Pham, Tuan V. Nguyen, John A. Eisman, Jean Woo, Ping-C. Leung, John Loughlin, Eleftheria Zeggini, Claus Christiansen, Fernando Rivadeneira, Joyce van Meurs, Andre G. Uitterlinden, Brynjolfur Mogensen, Helgi Jonsson, Thorvaldur Ingvarsson, Gunnar Sigurdsson, Rafn Benediktsson, Patrick Sulem, Ingileif Jonsdottir, Gisli Masson, Hilma Holm, Gudmundur L. Norddahl, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Kari Stefansson
Published 2019-05-01

GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures

by Unnur Styrkarsdottir, Olafur A. Stefansson, Kristbjorg Gunnarsdottir, Gudmar Thorleifsson, Sigrun H. Lund, Lilja Stefansdottir, Kristinn Juliusson, Arna B. Agustsdottir, Florian Zink, Gisli H. Halldorsson, Erna V. Ivarsdottir, Stefania Benonisdottir, Hakon Jonsson, Arnaldur Gylfason, Kristjan Norland, Katerina Trajanoska, Cindy G. Boer, Lorraine Southam, Jason C. S. Leung, Nelson L. S. Tang, Timothy C. Y. Kwok, Jenny S. W. Lee, Suzanne C. Ho, Inger Byrjalsen, Jacqueline R. Center, Seung Hun Lee, Jung-Min Koh, L. Stefan Lohmander, Lan T. Ho-Pham, Tuan V. Nguyen, John A. Eisman, Jean Woo, Ping-C. Leung, John Loughlin, Eleftheria Zeggini, Claus Christiansen, Fernando Rivadeneira, Joyce van Meurs, Andre G. Uitterlinden, Brynjolfur Mogensen, Helgi Jonsson, Thorvaldur Ingvarsson, Gunnar Sigurdsson, Rafn Benediktsson, Patrick Sulem, Ingileif Jonsdottir, Gisli Masson, Hilma Holm, Gudmundur L. Norddahl, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Kari Stefansson
Published 2019-05-01

WNT16 influences bone mineral density, cortical bone thickness, bone strength, and osteoporotic fracture risk.

by Hou-Feng Zheng, Jon H Tobias, Emma Duncan, David M Evans, Joel Eriksson, Lavinia Paternoster, Laura M Yerges-Armstrong, Terho Lehtimäki, Ulrica Bergström, Mika Kähönen, Paul J Leo, Olli Raitakari, Marika Laaksonen, Geoffrey C Nicholson, Jorma Viikari, Martin Ladouceur, Leo-Pekka Lyytikäinen, Carolina Medina-Gomez, Fernando Rivadeneira, Richard L Prince, Harri Sievanen, William D Leslie, Dan Mellström, John A Eisman, Sofia Movérare-Skrtic, David Goltzman, David A Hanley, Graeme Jones, Beate St Pourcain, Yongjun Xiao, Nicholas J Timpson, George Davey Smith, Ian R Reid, Susan M Ring, Philip N Sambrook, Magnus Karlsson, Elaine M Dennison, John P Kemp, Patrick Danoy, Adrian Sayers, Scott G Wilson, Maria Nethander, Eugene McCloskey, Liesbeth Vandenput, Richard Eastell, Jeff Liu, Tim Spector, Braxton D Mitchell, Elizabeth A Streeten, Robert Brommage, Ulrika Pettersson-Kymmer, Matthew A Brown, Claes Ohlsson, J Brent Richards, Mattias Lorentzon
Published 2012-07-01