Tetraspanins as Therapeutic Targets in Hematological Malignancy: A Concise Review

by Kyle Addison Beckwith, John C Byrd, Natarajan eMuthusamy
Published 2015-03-01

Hearing Loss due to Infiltration of the Tympanic Membrane by Chronic Lymphocytic Leukemia

by Jonathon B. Cohen, Robert Cavaliere, John C. Byrd, Leslie A. Andritsos
Published 2012-01-01

NF-κB Functions in Tumor Initiation by Suppressing the Surveillance of Both Innate and Adaptive Immune Cells

by David J. Wang, Nivedita M. Ratnam, John C. Byrd, Denis C. Guttridge
Published 2014-10-01

The PtdIns 3-kinase/Akt pathway regulates macrophage-mediated ADCC against B cell lymphoma.

by Trupti Joshi, Latha P Ganesan, Carolyn Cheney, Michael C Ostrowski, Natarajan Muthusamy, John C Byrd, Susheela Tridandapani
Published 2009-01-01

Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation

by Shaneice Mitchell, Pu Zhang, Matthew Cannon, Larry Beaver, Amy Lehman, Bonnie Harrington, Deepa Sampath, John C. Byrd, Rosa Lapalombella
Published 2021-06-01

How We Manage Patients With Chronic Lymphocytic Leukemia During the SARS-CoV-2 Pandemic

by Davide Rossi, Mazyar Shadman, Adalgisa Condoluci, Jennifer R. Brown, John C. Byrd, Gianluca Gaidano, Michael Hallek, Peter Hillmen, Anthony Mato, Emili Montserrat, Paolo Ghia
Published 2020-08-01

Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.

by Su-Lin Lee, Chih-Chien Chou, Hsiao-Ching Chuang, En-Chi Hsu, Po-Chen Chiu, Samuel K Kulp, John C Byrd, Ching-Shih Chen
Published 2013-01-01

Cotargeting of XPO1 Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Acute Myeloid Leukemia

by Lindsey T. Brinton, Steven Sher, Katie Williams, Daniel Canfield, Shelley Orwick, Ronni Wasmuth, Casey Cempre, Jordan Skinner, Amy Lehman, James S. Blachly, John C. Byrd, Rosa Lapalombella
Published 2020-06-01

CLEAR: coverage-based limiting-cell experiment analysis for RNA-seq

by Logan A. Walker, Michael G. Sovic, Chi-Ling Chiang, Eileen Hu, Jiyeon K. Denninger, Xi Chen, Elizabeth D. Kirby, John C. Byrd, Natarajan Muthusamy, Ralf Bundschuh, Pearlly Yan
Published 2020-02-01

Germline allele-specific expression of DAPK1 in chronic lymphocytic leukemia.

by Quan-Xiang Wei, Rainer Claus, Thomas Hielscher, Daniel Mertens, Aparna Raval, Christopher C Oakes, Stephan M Tanner, Albert de la Chapelle, John C Byrd, Stephan Stilgenbauer, Christoph Plass
Published 2013-01-01

Preclinical evaluation of the Hsp90 inhibitor SNX-5422 in ibrutinib resistant CLL

by Timothy L. Chen, Bonnie Harrington, Jean Truxall, Ronni Wasmuth, Alexander Prouty, Shelby Sloan, Amy M. Lehman, Deepa Sampath, Eric Orlemans, Robert A. Baiocchi, Lapo Alinari, John C. Byrd, Jennifer A. Woyach, Erin Hertlein
Published 2021-02-01

Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia

by Lindsey T. Brinton, Pu Zhang, Katie Williams, Daniel Canfield, Shelley Orwick, Steven Sher, Ronni Wasmuth, Larry Beaver, Casey Cempre, Jordan Skinner, Matthew Cannon, Mukul Govande, Bonnie Harrington, Amy Lehman, John C. Byrd, Rosa Lapalombella, James S. Blachly
Published 2020-10-01

Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.

by Wenjun Ni, Jia Ji, Zunyan Dai, Audrey Papp, Amy J Johnson, Sunjoo Ahn, Katherine L Farley, Thomas S Lin, James T Dalton, Xiaobai Li, David Jarjoura, John C Byrd, Wolfgang Sadee, Michael R Grever, Mitch A Phelps
Published 2010-11-01

Precision oncology in AML: validation of the prognostic value of the knowledge bank approach and suggestions for improvement

by Marius Bill, Krzysztof Mrózek, Brian Giacopelli, Jessica Kohlschmidt, Deedra Nicolet, Dimitrios Papaioannou, Ann-Kathrin Eisfeld, Jonathan E. Kolitz, Bayard L. Powell, Andrew J. Carroll, Richard M. Stone, Ramiro Garzon, John C. Byrd, Clara D. Bloomfield, Christopher C. Oakes
Published 2021-07-01

Activation of the FcgammaReceptorIIIa on human natural killer cells leads to increased expression of functional interleukin-21 receptor

by Elizabeth L. McMichael, Nicholas B. Courtney, Megan C. Duggan, Robert Wesolowski, Dionisia Quiroga, Sri Vidya Kondadasula, Lakhvir S. Atwal, Neela Bhave, Eric Luedke, Alena Cristina Jaime-Ramirez, Amanda R. Campbell, Xiaokui Mo, John C. Byrd, William E. Carson
Published 2017-05-01

Preclinical efficacy for a novel tyrosine kinase inhibitor, ArQule 531 against acute myeloid leukemia

by Ola A. Elgamal, Abeera Mehmood, Jae Yoon Jeon, Bridget Carmichael, Amy Lehman, Shelley J. Orwick, Jean Truxall, Virginia M. Goettl, Ronni Wasmuth, Minh Tran, Shaneice Mitchell, Rosa Lapalombella, Sudharshan Eathiraj, Brian Schwartz, Kimberly Stegmaier, Sharyn D. Baker, Erin Hertlein, John C. Byrd
Published 2020-01-01

Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT3‐ITD AML

by Daelynn R. Buelow, Stanley B. Pounds, Yong‐Dong Wang, Lei Shi, Yongjin Li, David Finkelstein, Sheila Shurtleff, Geoffrey Neale, Hiroto Inaba, Raul C. Ribeiro, Reid Palumbo, Dominique Garrison, Shelley J. Orwick, James S. Blachly, Karl Kroll, John C. Byrd, Tanja A. Gruber, Jeffrey E. Rubnitz, Sharyn D. Baker
Published 2019-11-01

Preclinical Evaluation of the Novel BTK Inhibitor Acalabrutinib in Canine Models of B-Cell Non-Hodgkin Lymphoma.

by Bonnie K Harrington, Heather L Gardner, Raquel Izumi, Ahmed Hamdy, Wayne Rothbaum, Kevin R Coombes, Todd Covey, Allard Kaptein, Michael Gulrajani, Bart Van Lith, Cecile Krejsa, Christopher C Coss, Duncan S Russell, Xiaoli Zhang, Bridget K Urie, Cheryl A London, John C Byrd, Amy J Johnson, William C Kisseberth
Published 2016-01-01

Characterization of a new chronic lymphocytic leukemia cell line for mechanistic in vitro and in vivo studies relevant to disease.

by Erin Hertlein, Kyle A Beckwith, Gerard Lozanski, Timothy L Chen, William H Towns, Amy J Johnson, Amy Lehman, Amy S Ruppert, Brad Bolon, Leslie Andritsos, Arletta Lozanski, Laura Rassenti, Weiqiang Zhao, Tiina M Jarvinen, Leigha Senter, Carlo M Croce, David E Symer, Albert de la Chapelle, Nyla A Heerema, John C Byrd
Published 2013-01-01

A precision medicine classification for treatment of acute myeloid leukemia in older patients

by Alice S. Mims, Jessica Kohlschmidt, Uma Borate, James S. Blachly, Shelley Orwick, Ann-Kathrin Eisfeld, Dimitrios Papaioannou, Deedra Nicolet, Krzysztof Mrόzek, Eytan Stein, Bhavana Bhatnagar, Richard M. Stone, Jonathan E. Kolitz, Eunice S. Wang, Bayard L. Powell, Amy Burd, Ross L. Levine, Brian J. Druker, Clara D. Bloomfield, John C. Byrd
Published 2021-06-01