Targeted genome editing in acute lymphoblastic leukemia: a review

by Adrián Montaño, Maribel Forero-Castro, Jesús-María Hernández-Rivas, Ignacio García-Tuñón, Rocío Benito
Published 2018-07-01

New Challenges in Targeting Signaling Pathways in Acute Lymphoblastic Leukemia by NGS Approaches: An Update

by Adrián Montaño, Maribel Forero-Castro, Darnel Marchena-Mendoza, Rocío Benito, Jesús María Hernández-Rivas
Published 2018-04-01

Clinical, cytogenetic, and molecular findings in a patient with ring chromosome 4: case report and literature review

by César Paz-y-Miño, Ana Proaño, Stella D. Verdezoto, Juan Luis García, Jesús María Hernández-Rivas, Paola E. Leone
Published 2019-11-01

Alteration in endoglin-related angiogenesis in refractory cytopenia with multilineage dysplasia.

by Mónica del Rey, Miguel Pericacho, Soraya Velasco, Eva Lumbreras, José Miguel López-Novoa, Jesús María Hernández-Rivas, Alicia Rodríguez-Barbero
Published 2013-01-01

<i>ETV6</i>/<i>RUNX1</i> Fusion Gene Abrogation Decreases the Oncogenicity of Tumour Cells in a Preclinical Model of Acute Lymphoblastic Leukaemia

by Adrián Montaño, Jose Luis Ordoñez, Verónica Alonso-Pérez, Jesús Hernández-Sánchez, Sandra Santos, Teresa González, Rocío Benito, Ignacio García-Tuñón, Jesús María Hernández-Rivas
Published 2020-01-01

The Evolving Landscape of Chronic Lymphocytic Leukemia on Diagnosis, Prognosis and Treatment

by Claudia Pérez-Carretero, Isabel González-Gascón-y-Marín, Ana E. Rodríguez-Vicente, Miguel Quijada-Álamo, José-Ángel Hernández-Rivas, María Hernández-Sánchez, Jesús María Hernández-Rivas
Published 2021-05-01

TET2 Overexpression in Chronic Lymphocytic Leukemia Is Unrelated to the Presence of TET2 Variations

by María Hernández-Sánchez, Ana Eugenia Rodríguez, Alexander Kohlmann, Rocío Benito, Juan Luis García, Alberto Risueño, Encarna Fermiñán, Javier De Las Rivas, Marcos González, Jesús-María Hernández-Rivas
Published 2014-01-01

NEMHESYS—European Perspective on the Implementation of Next-generation Sequencing Into Clinical Diagnostics

by Inmaculada Serramito-Gómez, Kathryn M. Clarke, Ana Eugenia Rodríguez-Vicente, Julie E. McGimpsey, María Abáigar, Carlos Barranquero Díez, Rocío Benito, Lars Bullinger, Ken I. Mills, Jesús María Hernández Rivas
Published 2021-03-01

The International Prognostic Index for Patients with Chronic Lymphocytic Leukemia Has the Higher Value in Predicting Overall Outcome Compared with the Barcelona-Brno Biomarkers Onl...

by Carolina Muñoz-Novas, María Poza-Santaella, Isabel González-Gascón y Marín, María Hernández-Sánchez, Ana-Eugenia Rodríguez-Vicente, María-Stefania Infante, Cecilia Heras, María-Ángeles Foncillas, Karen Marín, Jesús-María Hernández-Rivas, José-Ángel Hernández
Published 2018-01-01

Splice donor site sgRNAs enhance CRISPR/Cas9-mediated knockout efficiency.

by Ignacio García-Tuñón, Verónica Alonso-Pérez, Elena Vuelta, Sandra Pérez-Ramos, María Herrero, Lucía Méndez, Jesús María Hernández-Sánchez, Marta Martín-Izquierdo, Raquel Saldaña, Julián Sevilla, Fermín Sánchez-Guijo, Jesús María Hernández-Rivas, Manuel Sánchez-Martín
Published 2019-01-01

A Low Frequency of Losses in 11q Chromosome Is Associated with Better Outcome and Lower Rate of Genomic Mutations in Patients with Chronic Lymphocytic Leukemia.

by José Ángel Hernández, María Hernández-Sánchez, Ana Eugenia Rodríguez-Vicente, Vera Grossmann, Rosa Collado, Cecilia Heras, Anna Puiggros, Ana África Martín, Noemí Puig, Rocío Benito, Cristina Robledo, Julio Delgado, Teresa González, José Antonio Queizán, Josefina Galende, Ignacio de la Fuente, Guillermo Martín-Núñez, José María Alonso, Pau Abrisqueta, Elisa Luño, Isabel Marugán, Isabel González-Gascón, Francesc Bosch, Alexander Kohlmann, Marcos González, Blanca Espinet, Jesús María Hernández-Rivas, Jesús María Hernández-Rivas, Grupo Cooperativo Español de Citogenética Hematológica (GCECGH) and Grupo Español de Leucemia Linfática Crónica (GELLC)
Published 2015-01-01

Dissecting the role of TP53 alterations in del(11q) chronic lymphocytic leukemia

by Miguel Quijada‐Álamo, Claudia Pérez‐Carretero, María Hernández‐Sánchez, Ana‐Eugenia Rodríguez‐Vicente, Ana‐Belén Herrero, Jesús‐María Hernández‐Sánchez, Marta Martín‐Izquierdo, Sandra Santos‐Mínguez, Mónica del Rey, Teresa González, Araceli Rubio‐Martínez, Alfonso García de Coca, Julio Dávila‐Valls, José‐Ángel Hernández‐Rivas, Helen Parker, Jonathan C. Strefford, Rocío Benito, José‐Luis Ordóñez, Jesús‐María Hernández‐Rivas
Published 2021-02-01

Comprehensive Custom NGS Panel Validation for the Improvement of the Stratification of B-Acute Lymphoblastic Leukemia Patients

by Adrián Montaño, Jesús Hernández-Sánchez, Maribel Forero-Castro, María Matorra-Miguel, Eva Lumbreras, Cristina Miguel, Sandra Santos, Valentina Ramírez-Maldonado, José Luís Fuster, Natalia de Las Heras, Alfonso García-de Coca, Magdalena Sierra, Julio Dávila, Ignacio de la Fuente, Carmen Olivier, Juan Olazabal, Joaquín Martínez, Nerea Vega-García, Teresa González, Jesús María Hernández-Rivas, Rocío Benito
Published 2020-09-01

Biological significance of monoallelic and biallelic BIRC3 loss in del(11q) chronic lymphocytic leukemia progression

by Miguel Quijada-Álamo, María Hernández-Sánchez, Ana-Eugenia Rodríguez-Vicente, Claudia Pérez-Carretero, Alberto Rodríguez-Sánchez, Marta Martín-Izquierdo, Verónica Alonso-Pérez, Ignacio García-Tuñón, José María Bastida, María Jesús Vidal-Manceñido, Josefina Galende, Carlos Aguilar, José Antonio Queizán, Isabel González-Gascón y Marín, José-Ángel Hernández-Rivas, Rocío Benito, José Luis Ordóñez, Jesús-María Hernández-Rivas
Published 2021-07-01

A pediatric regimen for adolescents and young adults with Philadelphia chromosome‐negative acute lymphoblastic leukemia: Results of the ALLRE08 PETHEMA trial

by Josep‐Maria Ribera, Mireia Morgades, Pau Montesinos, Mar Tormo, Daniel Martínez‐Carballeira, José González‐Campos, Cristina Gil, Pere Barba, Raimundo García‐Boyero, Rosa Coll, María Pedreño, Jordi Ribera, Santiago Mercadal, Susana Vives, Andrés Novo, Eulàlia Genescà, Jesús‐María Hernández‐Rivas, Juan Bergua, María‐Luz Amigo, Ferran Vall‐Llovera, Pilar Martínez‐Sánchez, María Calbacho, Irene García‐Cadenas, Antoni Garcia‐Guiñon, María‐José Sánchez‐Sánchez, Marta Cervera, Evarist Feliu, Alberto Orfao, the PETHEMA Group, Spanish Society of Hematology
Published 2020-04-01

Next-generation sequencing and FISH studies reveal the appearance of gene mutations and chromosomal abnormalities in hematopoietic progenitors in chronic lymphocytic leukemia

by Miguel Quijada-Álamo, María Hernández-Sánchez, Cristina Robledo, Jesús-María Hernández-Sánchez, Rocío Benito, Adrián Montaño, Ana E. Rodríguez-Vicente, Dalia Quwaider, Ana-África Martín, María García-Álvarez, María Jesús Vidal-Manceñido, Gonzalo Ferrer-Garrido, María-Pilar Delgado-Beltrán, Josefina Galende, Juan-Nicolás Rodríguez, Guillermo Martín-Núñez, José-María Alonso, Alfonso García de Coca, José A. Queizán, Magdalena Sierra, Carlos Aguilar, Alexander Kohlmann, José-Ángel Hernández, Marcos González, Jesús-María Hernández-Rivas
Published 2017-04-01

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

by Eloy F. Robles, Maria Mena-Varas, Laura Barrio, Sara V. Merino-Cortes, Péter Balogh, Ming-Qing Du, Takashi Akasaka, Anton Parker, Sergio Roa, Carlos Panizo, Idoia Martin-Guerrero, Reiner Siebert, Victor Segura, Xabier Agirre, Laura Macri-Pellizeri, Beatriz Aldaz, Amaia Vilas-Zornoza, Shaowei Zhang, Sarah Moody, Maria Jose Calasanz, Thomas Tousseyn, Cyril Broccardo, Pierre Brousset, Elena Campos-Sanchez, Cesar Cobaleda, Isidro Sanchez-Garcia, Jose Luis Fernandez-Luna, Ricardo Garcia-Muñoz, Esther Pena, Beatriz Bellosillo, Antonio Salar, Maria Joao Baptista, Jesús Maria Hernandez-Rivas, Marcos Gonzalez, Maria Jose Terol, Joan Climent, Antonio Ferrandez, Xavier Sagaert, Ari M. Melnick, Felipe Prosper, David G. Oscier, Yolanda R. Carrasco, Martin J. S. Dyer, Jose A. Martinez-Climent
Published 2016-06-01