Genome-wide detection of genes targeted by non-Ig somatic hypermutation in lymphoma.

by Yanwen Jiang, T David Soong, Ling Wang, Ari M Melnick, Olivier Elemento
Published 2012-01-01

How Biophysical Forces Regulate Human B Cell Lymphomas

by F. Apoorva, Alexander M. Loiben, Shivem B. Shah, Alberto Purwada, Lorena Fontan, Rebecca Goldstein, Brian J. Kirby, Ari M. Melnick, Benjamin D. Cosgrove, Ankur Singh
Published 2018-04-01

EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop

by Wendy Béguelin, Martín A. Rivas, María T. Calvo Fernández, Matt Teater, Alberto Purwada, David Redmond, Hao Shen, Matt F. Challman, Olivier Elemento, Ankur Singh, Ari M. Melnick
Published 2017-10-01

MTA2/NuRD Regulates B Cell Development and Cooperates with OCA-B in Controlling the Pre-B to Immature B Cell Transition

by Xiangdong Lu, Chi-Shuen Chu, Terry Fang, Violeta Rayon-Estrada, Fang Fang, Alina Patke, Ye Qian, Stephen H. Clarke, Ari M. Melnick, Yi Zhang, F. Nina Papavasiliou, Robert G. Roeder
Published 2019-07-01

The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy.

by Marie-Sophie Fabre, Nicole M Stanton, Tania L Slatter, Samuel Lee, Dinindu Senanayake, Rosemary M A Gordon, M Leticia Castro, Matthew R Rowe, Ahmad Taha, Janice A Royds, Noelyn Hung, Ari M Melnick, Melanie J McConnell
Published 2020-01-01

The Impact of Heterogeneity on Single-Cell Sequencing

by Samantha L. Goldman, Samantha L. Goldman, Matthew MacKay, Matthew MacKay, Ebrahim Afshinnekoo, Ebrahim Afshinnekoo, Ebrahim Afshinnekoo, Ari M. Melnick, Shuxiu Wu, Shuxiu Wu, Christopher E. Mason, Christopher E. Mason, Christopher E. Mason, Christopher E. Mason
Published 2019-03-01

Targeted detection and quantitation of histone modifications from 1,000 cells.

by Nebiyu A Abshiru, Jacek W Sikora, Jeannie M Camarillo, Juliette A Morris, Philip D Compton, Tak Lee, Yaseswini Neelamraju, Samuel Haddox, Caroline Sheridan, Martin Carroll, Larry D Cripe, Martin S Tallman, Elisabeth M Paietta, Ari M Melnick, Paul M Thomas, Francine E Garrett-Bakelman, Neil L Kelleher
Published 2020-01-01

Clonal hematopoiesis before, during, and after human spaceflight

by Nuria Mencia-Trinchant, Matthew J. MacKay, Christopher Chin, Ebrahim Afshinnekoo, Jonathan Foox, Cem Meydan, Daniel Butler, Christopher Mozsary, Nicholas A. Vernice, Charlotte Darby, Michael C. Schatz, Susan M. Bailey, Ari M. Melnick, Monica L. Guzman, Kelly Bolton, Lior Z. Braunstein, Francine Garrett-Bakelman, Ross L. Levine, Duane C. Hassane, Christopher E. Mason
Published 2021-02-01

Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL

by Alessandro Pastore, Federico Gaiti, Sydney X. Lu, Ryan M. Brand, Scott Kulm, Ronan Chaligne, Hongcang Gu, Kevin Y. Huang, Elena K. Stamenova, Wendy Béguelin, Yanwen Jiang, Rafael C. Schulman, Kyu-Tae Kim, Alicia Alonso, John N. Allan, Richard R. Furman, Andreas Gnirke, Catherine J. Wu, Ari M. Melnick, Alexander Meissner, Bradley E. Bernstein, Omar Abdel-Wahab, Dan A. Landau
Published 2019-04-01

Cohesin Core Complex Gene Dosage Contributes to Germinal Center Derived Lymphoma Phenotypes and Outcomes

by Martin A. Rivas, Ceyda Durmaz, Andreas Kloetgen, Cristopher R. Chin, Cristopher R. Chin, Zhengming Chen, Bhavneet Bhinder, Bhavneet Bhinder, Bhavneet Bhinder, Amnon Koren, Aaron D. Viny, Aaron D. Viny, Christopher D. Scharer, Jeremy M. Boss, Olivier Elemento, Olivier Elemento, Olivier Elemento, Christopher E. Mason, Christopher E. Mason, Christopher E. Mason, Christopher E. Mason, Ari M. Melnick
Published 2021-09-01

Cell-free DNA (cfDNA) and Exosome Profiling from a Year-Long Human Spaceflight Reveals Circulating Biomarkers

by Daniela Bezdan, Kirill Grigorev, Cem Meydan, Fanny A. Pelissier Vatter, Michele Cioffi, Varsha Rao, Matthew MacKay, Kiichi Nakahira, Philip Burnham, Ebrahim Afshinnekoo, Craig Westover, Daniel Butler, Chris Mozsary, Timothy Donahoe, Jonathan Foox, Tejaswini Mishra, Serena Lucotti, Brinda K. Rana, Ari M. Melnick, Haiying Zhang, Irina Matei, David Kelsen, Kenneth Yu, David C. Lyden, Lynn Taylor, Susan M. Bailey, Michael P. Snyder, Francine E. Garrett-Bakelman, Stephan Ossowski, Iwijn De Vlaminck, Christopher E. Mason
Published 2020-12-01

Homeobox NKX2-3 promotes marginal-zone lymphomagenesis by activating B-cell receptor signalling and shaping lymphocyte dynamics

by Eloy F. Robles, Maria Mena-Varas, Laura Barrio, Sara V. Merino-Cortes, Péter Balogh, Ming-Qing Du, Takashi Akasaka, Anton Parker, Sergio Roa, Carlos Panizo, Idoia Martin-Guerrero, Reiner Siebert, Victor Segura, Xabier Agirre, Laura Macri-Pellizeri, Beatriz Aldaz, Amaia Vilas-Zornoza, Shaowei Zhang, Sarah Moody, Maria Jose Calasanz, Thomas Tousseyn, Cyril Broccardo, Pierre Brousset, Elena Campos-Sanchez, Cesar Cobaleda, Isidro Sanchez-Garcia, Jose Luis Fernandez-Luna, Ricardo Garcia-Muñoz, Esther Pena, Beatriz Bellosillo, Antonio Salar, Maria Joao Baptista, Jesús Maria Hernandez-Rivas, Marcos Gonzalez, Maria Jose Terol, Joan Climent, Antonio Ferrandez, Xavier Sagaert, Ari M. Melnick, Felipe Prosper, David G. Oscier, Yolanda R. Carrasco, Martin J. S. Dyer, Jose A. Martinez-Climent
Published 2016-06-01

Shotgun transcriptome, spatial omics, and isothermal profiling of SARS-CoV-2 infection reveals unique host responses, viral diversification, and drug interactions

by Daniel Butler, Christopher Mozsary, Cem Meydan, Jonathan Foox, Joel Rosiene, Alon Shaiber, David Danko, Ebrahim Afshinnekoo, Matthew MacKay, Fritz J. Sedlazeck, Nikolay A. Ivanov, Maria Sierra, Diana Pohle, Michael Zietz, Undina Gisladottir, Vijendra Ramlall, Evan T. Sholle, Edward J. Schenck, Craig D. Westover, Ciaran Hassan, Krista Ryon, Benjamin Young, Chandrima Bhattacharya, Dianna L. Ng, Andrea C. Granados, Yale A. Santos, Venice Servellita, Scot Federman, Phyllis Ruggiero, Arkarachai Fungtammasan, Chen-Shan Chin, Nathaniel M. Pearson, Bradley W. Langhorst, Nathan A. Tanner, Youngmi Kim, Jason W. Reeves, Tyler D. Hether, Sarah E. Warren, Michael Bailey, Justyna Gawrys, Dmitry Meleshko, Dong Xu, Mara Couto-Rodriguez, Dorottya Nagy-Szakal, Joseph Barrows, Heather Wells, Niamh B. O’Hara, Jeffrey A. Rosenfeld, Ying Chen, Peter A. D. Steel, Amos J. Shemesh, Jenny Xiang, Jean Thierry-Mieg, Danielle Thierry-Mieg, Angelika Iftner, Daniela Bezdan, Elizabeth Sanchez, Thomas R. Campion, John Sipley, Lin Cong, Arryn Craney, Priya Velu, Ari M. Melnick, Sagi Shapira, Iman Hajirasouliha, Alain Borczuk, Thomas Iftner, Mirella Salvatore, Massimo Loda, Lars F. Westblade, Melissa Cushing, Shixiu Wu, Shawn Levy, Charles Chiu, Robert E. Schwartz, Nicholas Tatonetti, Hanna Rennert, Marcin Imielinski, Christopher E. Mason
Published 2021-03-01