Novel insulin sensitizer modulates nutrient sensing pathways and maintains β-cell phenotype in human islets.

by Nidhi Rohatgi, Haytham Aly, Connie A Marshall, William G McDonald, Rolf F Kletzien, Jerry R Colca, Michael L McDaniel
Published 2013-01-01

Inhibiting the mitochondrial pyruvate carrier does not ameliorate synucleinopathy in the absence of inflammation or metabolic deficits

by Wouter Peelaerts, Liza Bergkvist, Sonia George, Michaela Johnson, Lindsay Meyerdirk, Emily Schulz, Jennifer A. Steiner, Zachary Madaj, Jiyan Ma, Katelyn Becker, K. Peter R. Nilsson, Jerry R. Colca, Patrik Brundin
Published 2020-11-01

Mitochondrial Pyruvate Carrier 2 Hypomorphism in Mice Leads to Defects in Glucose-Stimulated Insulin Secretion

by Patrick A. Vigueira, Kyle S. McCommis, George G. Schweitzer, Maria S. Remedi, Kari T. Chambers, Xiaorong Fu, William G. McDonald, Serena L. Cole, Jerry R. Colca, Rolf F. Kletzien, Shawn C. Burgess, Brian N. Finck
Published 2014-06-01

Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins.

by Jerry R Colca, William G McDonald, Gregory S Cavey, Serena L Cole, Danielle D Holewa, Angela S Brightwell-Conrad, Cindy L Wolfe, Jean S Wheeler, Kristin R Coulter, Peter M Kilkuskie, Elena Gracheva, Yulia Korshunova, Michelle Trusgnich, Robert Karr, Sandra E Wiley, Ajit S Divakaruni, Anne N Murphy, Patrick A Vigueira, Brian N Finck, Rolf F Kletzien
Published 2013-01-01