Serum Amyloid P Component Ameliorates Neurological Damage Caused by Expressing a Lysozyme Variant in the Central Nervous System of Drosophila melanogaster.

by Linda Helmfors, Liza Bergkvist, Ann-Christin Brorsson
Published 2016-01-01

AβPP processing results in greater toxicity per amount of Aβ1-42 than individually expressed and secreted Aβ1-42 in Drosophila melanogaster

by Liza Bergkvist, Linnea Sandin, Katarina Kågedal, Ann-Christin Brorsson
Published 2016-08-01

Serum amyloid P component promotes formation of distinct aggregated lysozyme morphologies and reduces toxicity in Drosophila flies expressing F57I lysozyme.

by Liza Bergkvist, Daniel R Richards, Ana Bernardo-Gancedo, Janet R Kumita, Peter R Nilsson, Ann-Christin Brorsson
Published 2020-01-01

Mapping pathogenic processes contributing to neurodegeneration in Drosophila models of Alzheimer's disease

by Liza Bergkvist, Zhen Du, Greta Elovsson, Hanna Appelqvist, Laura S. Itzhaki, Janet R. Kumita, Katarina Kågedal, Ann‐Christin Brorsson
Published 2020-03-01

Heterozygous GBA D409V and ATP13a2 mutations do not exacerbate pathological α-synuclein spread in the prodromal preformed fibrils model in young mice

by Michaela E. Johnson, Liza Bergkvist, Lucas Stetzik, Jennifer A. Steiner, Lindsay Meyerdirk, Emily Schulz, Emily Wolfrum, Kelvin C. Luk, Daniel W. Wesson, Dimitri Krainc, Patrik Brundin
Published 2021-11-01

Inhibiting the mitochondrial pyruvate carrier does not ameliorate synucleinopathy in the absence of inflammation or metabolic deficits

by Wouter Peelaerts, Liza Bergkvist, Sonia George, Michaela Johnson, Lindsay Meyerdirk, Emily Schulz, Jennifer A. Steiner, Zachary Madaj, Jiyan Ma, Katelyn Becker, K. Peter R. Nilsson, Jerry R. Colca, Patrik Brundin
Published 2020-11-01