Age and microenvironment outweigh genetic influence on the Zucker rat microbiome.

by Hannah Lees, Jonathan Swann, Simon M Poucher, Jeremy K Nicholson, Elaine Holmes, Ian D Wilson, Julian R Marchesi
Published 2014-01-01

Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier

by Lesley Hoyles, Tom Snelling, Umm-Kulthum Umlai, Jeremy K. Nicholson, Simon R. Carding, Robert C. Glen, Simon McArthur
Published 2018-03-01

Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery

by Arnaud M. Wolfer, Alasdair J. Scott, Claudia Rueb, Mathieu Gaudin, Ara Darzi, Jeremy K. Nicholson, Elaine Holmes, James M. Kinross
Published 2017-04-01

Roux-en-Y gastric bypass surgery in Zucker rats induces bacterial and systemic metabolic changes independent of caloric restriction-induced weight loss

by Florian Seyfried, Jutarop Phetcharaburanin, Maria Glymenaki, Arno Nordbeck, Mohammed Hankir, Jeremy K Nicholson, Elaine Holmes, Julian R. Marchesi, Jia V. Li
Published 2021-01-01

Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment

by Marie C. Lewis, Claire A. Merrifield, Bernard Berger, Olivier Cloarec, Swantje Duncker, Annick Mercenier, Jeremy K. Nicholson, Elaine Holmes, Mick Bailey
Published 2017-07-01

Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia.

by Elaine Holmes, Tsz M Tsang, Jeffrey T-J Huang, F Markus Leweke, Dagmar Koethe, Christoph W Gerth, Brit M Nolden, Sonja Gross, Daniela Schreiber, Jeremy K Nicholson, Sabine Bahn
Published 2006-08-01

Neuroendocrine Neoplasms: Identification Of Novel Metabolic Circuits of Potential Diagnostic Utility

by Beatriz Jiménez, Mei Ran Abellona U, Panagiotis Drymousis, Michael Kyriakides, Ashley K. Clift, Daniel S. K. Liu, Eleanor Rees, Elaine Holmes, Jeremy K. Nicholson, James M. Kinross, Andrea Frilling
Published 2021-01-01

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

by Richard G. Brown, Julian R. Marchesi, Yun S. Lee, Ann Smith, Benjamin Lehne, Lindsay M. Kindinger, Vasso Terzidou, Elaine Holmes, Jeremy K. Nicholson, Phillip R. Bennett, David A. MacIntyre
Published 2018-01-01

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice.

by Jane F Fearnside, Marc-Emmanuel Dumas, Alice R Rothwell, Steven P Wilder, Olivier Cloarec, Ayo Toye, Christine Blancher, Elaine Holmes, Roger Tatoud, Richard H Barton, James Scott, Jeremy K Nicholson, Dominique Gauguier
Published 2008-02-01

Diagnostic Potential of the Plasma Lipidome in Infectious Disease: Application to Acute SARS-CoV-2 Infection

by Nicola Gray, Nathan G. Lawler, Annie Xu Zeng, Monique Ryan, Sze How Bong, Berin A. Boughton, Maider Bizkarguenaga, Chiara Bruzzone, Nieves Embade, Julien Wist, Elaine Holmes, Oscar Millet, Jeremy K. Nicholson, Luke Whiley
Published 2021-07-01

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol

by Pierre Zalloua, Hanane Kadar, Essa Hariri, Layal Abi Farraj, Francois Brial, Lyamine Hedjazi, Aurelie Le Lay, Alexandre Colleu, Justine Dubus, David Touboul, Fumihiko Matsuda, Mark Lathrop, Jeremy K. Nicholson, Marc-Emmanuel Dumas, Dominique Gauguier
Published 2019-02-01

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota

by Lesley Hoyles, Maria L. Jiménez-Pranteda, Julien Chilloux, Francois Brial, Antonis Myridakis, Thomas Aranias, Christophe Magnan, Glenn R. Gibson, Jeremy D. Sanderson, Jeremy K. Nicholson, Dominique Gauguier, Anne L. McCartney, Marc-Emmanuel Dumas
Published 2018-04-01

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

by Marc-Emmanuel Dumas, Alice R. Rothwell, Lesley Hoyles, Thomas Aranias, Julien Chilloux, Sophie Calderari, Elisa M. Noll, Noémie Péan, Claire L. Boulangé, Christine Blancher, Richard H. Barton, Quan Gu, Jane F. Fearnside, Chloé Deshayes, Christophe Hue, James Scott, Jeremy K. Nicholson, Dominique Gauguier
Published 2017-07-01

Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype

by Jia V. Li, Hutan Ashrafian, Magali Sarafian, Daniel Homola, Laura Rushton, Grace Barker, Paula Momo Cabrera, Matthew R. Lewis, Ara Darzi, Edward Lin, Nana Adwoa Gletsu-Miller, Stephen L. Atkin, Thozhukat Sathyapalan, Nigel J. Gooderham, Jeremy K. Nicholson, Julian R. Marchesi, Thanos Athanasiou, Elaine Holmes
Published 2021-06-01

Urinary metabolic phenotyping for Alzheimer’s disease

by Natalja Kurbatova, Manik Garg, Luke Whiley, Elena Chekmeneva, Beatriz Jiménez, María Gómez-Romero, Jake Pearce, Torben Kimhofer, Ellie D’Hondt, Hilkka Soininen, Iwona Kłoszewska, Patrizia Mecocci, Magda Tsolaki, Bruno Vellas, Dag Aarsland, Alejo Nevado-Holgado, Benjamine Liu, Stuart Snowden, Petroula Proitsi, Nicholas J. Ashton, Abdul Hye, Cristina Legido-Quigley, Matthew R. Lewis, Jeremy K. Nicholson, Elaine Holmes, Alvis Brazma, Simon Lovestone
Published 2020-12-01

Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome

by Jordi Mayneris-Perxachs, Marina Cardellini, Lesley Hoyles, Jèssica Latorre, Francesca Davato, José Maria Moreno-Navarrete, María Arnoriaga-Rodríguez, Matteo Serino, James Abbott, Richard H. Barton, Josep Puig, Xavier Fernández-Real, Wifredo Ricart, Christopher Tomlinson, Mark Woodbridge, Paolo Gentileschi, Sarah A. Butcher, Elaine Holmes, Jeremy K. Nicholson, Vicente Pérez-Brocal, Andrés Moya, Donald Mc Clain, Rémy Burcelin, Marc-Emmanuel Dumas, Massimo Federici, José-Manuel Fernández-Real
Published 2021-05-01

A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection.

by George Nicholson, Mattias Rantalainen, Jia V Li, Anthony D Maher, Daniel Malmodin, Kourosh R Ahmadi, Johan H Faber, Amy Barrett, Josine L Min, N William Rayner, Henrik Toft, Maria Krestyaninova, Juris Viksna, Sudeshna Guha Neogi, Marc-Emmanuel Dumas, Ugis Sarkans, MolPAGE Consortium, Peter Donnelly, Thomas Illig, Jerzy Adamski, Karsten Suhre, Maxine Allen, Krina T Zondervan, Tim D Spector, Jeremy K Nicholson, John C Lindon, Dorrit Baunsgaard, Elaine Holmes, Mark I McCarthy, Chris C Holmes
Published 2011-09-01

Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children

by Chenhong Zhang, Aihua Yin, Hongde Li, Ruirui Wang, Guojun Wu, Jian Shen, Menghui Zhang, Linghua Wang, Yaping Hou, Haimei Ouyang, Yan Zhang, Yinan Zheng, Jicheng Wang, Xiaofei Lv, Yulan Wang, Feng Zhang, Benhua Zeng, Wenxia Li, Feiyan Yan, Yufeng Zhao, Xiaoyan Pang, Xiaojun Zhang, Huaqing Fu, Feng Chen, Naisi Zhao, Bruce R. Hamaker, Laura C. Bridgewater, David Weinkove, Karine Clement, Joel Dore, Elaine Holmes, Huasheng Xiao, Guoping Zhao, Shengli Yang, Peer Bork, Jeremy K. Nicholson, Hong Wei, Huiru Tang, Xiaozhuang Zhang, Liping Zhao
Published 2015-08-01