Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine

by Shunxing Rong, Jeffrey G. McDonald, Luke J. Engelking
Published 2017-10-01

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways

by Matthew A Mitsche, Jeffrey G McDonald, Helen H Hobbs, Jonathan C Cohen
Published 2015-06-01

A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma

by Jeffrey G. McDonald, Daniel D. Smith, Ashlee R. Stiles, David W. Russell
Published 2012-07-01

Insights into lipid accumulation in skeletal muscle in dysferlin-deficient mice

by Anil K. Agarwal, Katie Tunison, Matthew A. Mitsche, Jeffrey G. McDonald, Abhimanyu Garg
Published 2019-12-01

Structural basis for human sterol isomerase in cholesterol biosynthesis and multidrug recognition

by Tao Long, Abdirahman Hassan, Bonne M Thompson, Jeffrey G McDonald, Jiawei Wang, Xiaochun Li
Published 2019-06-01

Three-phase liquid extraction: a simple and fast method for lipidomic workflows[S]

by Gonçalo Vale, Sarah A. Martin, Matthew A. Mitsche, Bonne M. Thompson, Kaitlyn M. Eckert, Jeffrey G. McDonald
Published 2019-03-01

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice

by Shunxing Rong, Víctor A Cortés, Shirya Rashid, Norma N Anderson, Jeffrey G McDonald, Guosheng Liang, Young-Ah Moon, Robert E Hammer, Jay D Horton
Published 2017-02-01

Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice

by Youngah Jo, Jason S Hamilton, Seonghwan Hwang, Kristina Garland, Gennipher A Smith, Shan Su, Iris Fuentes, Sudha Neelam, Bonne M Thompson, Jeffrey G McDonald, Russell A DeBose-Boyd
Published 2019-02-01

Measurement of lipogenic flux by deuterium resolved mass spectrometry

by Xiaorong Fu, Stanisław Deja, Justin A. Fletcher, Norma N. Anderson, Monika Mizerska, Gonçalo Vale, Jeffrey D. Browning, Jay D. Horton, Jeffrey G. McDonald, Matthew A. Mitsche, Shawn C. Burgess
Published 2021-06-01

Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress

by Suneeta Chimalapati, Marcela de Souza Santos, Alexander E Lafrance, Ann Ray, Wan-Ru Lee, Giomar Rivera-Cancel, Gonçalo Vale, Krzysztof Pawlowski, Matthew A Mitsche, Jeffrey G McDonald, Jen Liou, Kim Orth
Published 2020-08-01

27-Hydroxycholesterol Promotes Cell-Autonomous, ER-Positive Breast Cancer Growth

by Qian Wu, Tomonori Ishikawa, Rosa Sirianni, Hao Tang, Jeffrey G. McDonald, Ivan S. Yuhanna, Bonne Thompson, Luc Girard, Chieko Mineo, Rolf A. Brekken, Michihisa Umetani, David M. Euhus, Yang Xie, Philip W. Shaul
Published 2013-11-01

Cholesterol accessibility at the ciliary membrane controls hedgehog signaling

by Maia Kinnebrew, Ellen J Iverson, Bhaven B Patel, Ganesh V Pusapati, Jennifer H Kong, Kristen A Johnson, Giovanni Luchetti, Kaitlyn M Eckert, Jeffrey G McDonald, Douglas F Covey, Christian Siebold, Arun Radhakrishnan, Rajat Rohatgi
Published 2019-10-01

Subcellular organelle lipidomics in TLR-4-activated macrophages1[S]

by Alexander Y. Andreyev, Eoin Fahy, Ziqiang Guan, Samuel Kelly, Xiang Li, Jeffrey G. McDonald, Stephen Milne, David Myers, Hyejung Park, Andrea Ryan, Bonne M. Thompson, Elaine Wang, Yihua Zhao, H. Alex Brown, Alfred H. Merrill, Christian R.H. Raetz, David W. Russell, Shankar Subramaniam, Edward A. Dennis
Published 2010-09-01

Glucagon Receptor Antagonism Improves Glucose Metabolism and Cardiac Function by Promoting AMP-Mediated Protein Kinase in Diabetic Mice

by Ankit X. Sharma, Ezekiel B. Quittner-Strom, Young Lee, Joshua A. Johnson, Sarah A. Martin, Xinxin Yu, Jianping Li, John Lu, Zheqing Cai, Shiuhwei Chen, May-yun Wang, Yiyi Zhang, Mackenzie J. Pearson, Andie C. Dorn, Jeffrey G. McDonald, Ruth Gordillo, Hai Yan, Dung Thai, Zhao V. Wang, Roger H. Unger, William L. Holland
Published 2018-02-01

Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans

by Min Ni, Ashley Solmonson, Chunxiao Pan, Chendong Yang, Dan Li, Ashley Notzon, Ling Cai, Gerardo Guevara, Lauren G. Zacharias, Brandon Faubert, Hieu S. Vu, Lei Jiang, Bookyung Ko, Noriko Merida Morales, Jimin Pei, Gonçalo Vale, Dinesh Rakheja, Nick V. Grishin, Jeffrey G. McDonald, Garrett K. Gotway, Markey C. McNutt, Juan M. Pascual, Ralph J. DeBerardinis
Published 2019-04-01

Lipidomics reveals a remarkable diversity of lipids in human plasma1[S]

by Oswald Quehenberger, Aaron M. Armando, Alex H. Brown, Stephen B. Milne, David S. Myers, Alfred H. Merrill, Sibali Bandyopadhyay, Kristin N. Jones, Samuel Kelly, Rebecca L. Shaner, Cameron M. Sullards, Elaine Wang, Robert C. Murphy, Robert M. Barkley, Thomas J. Leiker, Christian R.H. Raetz, Ziqiang Guan, Gregory M. Laird, David A. Six, David W. Russell, Jeffrey G. McDonald, Shankar Subramaniam, Eoin Fahy, Edward A. Dennis
Published 2010-11-01

Biomarkers of NAFLD progression: a lipidomics approach to an epidemic1[S]

by D.Lee Gorden, David S. Myers, Pavlina T. Ivanova, Eoin Fahy, Mano R. Maurya, Shakti Gupta, Jun Min, Nathanael J. Spann, Jeffrey G. McDonald, Samuel L. Kelly, Jingjing Duan, M.Cameron Sullards, Thomas J. Leiker, Robert M. Barkley, Oswald Quehenberger, Aaron M. Armando, Stephen B. Milne, Thomas P. Mathews, Michelle D. Armstrong, Chijun Li, Willie V. Melvin, Ronald H. Clements, M.Kay Washington, Alisha M. Mendonsa, Joseph L. Witztum, Ziqiang Guan, Christopher K. Glass, Robert C. Murphy, Edward A. Dennis, Alfred H. Merrill, Jr., David W. Russell, Shankar Subramaniam, H.Alex Brown
Published 2015-03-01