Sheep Monoclonal Antibodies Prevent Systemic Effects of Botulinum Neurotoxin A1

by Charles B. Shoemaker, Peter Harrison, Saul Tzipori, Karen Baldwin, Kwasi Ofori, Julia Hill, Chase McCann, Jean Mukherjee
Published 2012-12-01

Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein.

by Jean Mukherjee, Igor Dmitriev, Michelle Debatis, Jacqueline M Tremblay, Gillian Beamer, Elena A Kashentseva, David T Curiel, Charles B Shoemaker
Published 2014-01-01

Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin

by Nai-Jia Huang, Novalia Pishesha, Jean Mukherjee, Sicai Zhang, Rhogerry Deshycka, Valentino Sudaryo, Min Dong, Charles B. Shoemaker, Harvey F. Lodish
Published 2017-09-01

Evidence of Influenza A in Wild Norway Rats (Rattus norvegicus) in Boston, Massachusetts

by Charles O. Cummings, Nichola J. Hill, Wendy B. Puryear, Benjamin Rogers, Jean Mukherjee, Jessica H. Leibler, Marieke H. Rosenbaum, Jonathan A. Runstadler
Published 2019-03-01

A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model.

by Jean Mukherjee, Jacqueline M Tremblay, Clinton E Leysath, Kwasi Ofori, Karen Baldwin, Xiaochuan Feng, Daniela Bedenice, Robert P Webb, Patrick M Wright, Leonard A Smith, Saul Tzipori, Charles B Shoemaker
Published 2012-01-01

Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function

by Jacqueline M. Tremblay, Edwin Vazquez-Cintron, Kwok-Ho Lam, Jean Mukherjee, Daniela Bedenice, Celinia A. Ondeck, Matthieu T. Conroy, Skylar M. L. Bodt, Brittany M. Winner, Robert P. Webb, Konstantin Ichtchenko, Rongsheng Jin, Patrick M. McNutt, Charles B. Shoemaker
Published 2020-09-01