A molecular genetic study of the variations in metabolic function during schistosome development

by Patrick J. Skelly, Charles B. Shoemaker
Published 1995-04-01

Accelerated neuronal cell recovery from Botulinum neurotoxin intoxication by targeted ubiquitination.

by Chueh-Ling Kuo, George A Oyler, Charles B Shoemaker
Published 2011-01-01

Two VHH Antibodies Neutralize Botulinum Neurotoxin E1 by Blocking Its Membrane Translocation in Host Cells

by Kwok-Ho Lam, Kay Perry, Charles B. Shoemaker, Rongsheng Jin
Published 2020-09-01

Differential neutralizing activities of a single domain camelid antibody (VHH) specific for ricin toxin's binding subunit (RTB).

by Cristina Herrera, David J Vance, Leslie E Eisele, Charles B Shoemaker, Nicholas J Mantis
Published 2014-01-01

Intraspecific epitopic variation in a carbohydrate antigen exposed on the surface of Trichostrongylus colubriformis infective L3 larvae.

by David R Maass, Gavin B Harrison, Warwick N Grant, Wayne R Hein, Charles B Shoemaker
Published 2009-09-01

Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism

by Greice Krautz-Peterson, Yongrong Zhang, Kevin Chen, George A. Oyler, Hanping Feng, Charles B. Shoemaker
Published 2012-01-01

Suppressing glucose transporter gene expression in schistosomes impairs parasite feeding and decreases survival in the mammalian host.

by Greice Krautz-Peterson, Mariana Simoes, Zahra Faghiri, David Ndegwa, Guilherme Oliveira, Charles B Shoemaker, Patrick J Skelly
Published 2010-06-01

Sheep Monoclonal Antibodies Prevent Systemic Effects of Botulinum Neurotoxin A1

by Charles B. Shoemaker, Peter Harrison, Saul Tzipori, Karen Baldwin, Kwasi Ofori, Julia Hill, Chase McCann, Jean Mukherjee
Published 2012-12-01

Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein.

by Jean Mukherjee, Igor Dmitriev, Michelle Debatis, Jacqueline M Tremblay, Gillian Beamer, Elena A Kashentseva, David T Curiel, Charles B Shoemaker
Published 2014-01-01

Genetically engineered red cells expressing single domain camelid antibodies confer long-term protection against botulinum neurotoxin

by Nai-Jia Huang, Novalia Pishesha, Jean Mukherjee, Sicai Zhang, Rhogerry Deshycka, Valentino Sudaryo, Min Dong, Charles B. Shoemaker, Harvey F. Lodish
Published 2017-09-01

Schistosoma mansoni Infection of Mice, Rats and Humans Elicits a Strong Antibody Response to a Limited Number of Reduction-Sensitive Epitopes on Five Major Tegumental Membrane Prot...

by Greice Krautz-Peterson, Michelle Debatis, Jacqueline M Tremblay, Sergio C Oliveira, Akram A Da'dara, Patrick J Skelly, Charles B Shoemaker
Published 2017-01-01

A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding

by Guorui Yao, Kwok-ho Lam, Jasmin Weisemann, Lisheng Peng, Nadja Krez, Kay Perry, Charles B. Shoemaker, Min Dong, Andreas Rummel, Rongsheng Jin
Published 2017-08-01

Structural Insights into Rational Design of Single-Domain Antibody-Based Antitoxins against Botulinum Neurotoxins

by Kwok-ho Lam, Jacqueline M. Tremblay, Edwin Vazquez-Cintron, Kay Perry, Celinia Ondeck, Robert P. Webb, Patrick M. McNutt, Charles B. Shoemaker, Rongsheng Jin
Published 2020-02-01

A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model.

by Jean Mukherjee, Jacqueline M Tremblay, Clinton E Leysath, Kwasi Ofori, Karen Baldwin, Xiaochuan Feng, Daniela Bedenice, Robert P Webb, Patrick M Wright, Leonard A Smith, Saul Tzipori, Charles B Shoemaker
Published 2012-01-01

On the three-finger protein domain fold and CD59-like proteins in Schistosoma mansoni.

by Leonardo P Farias, Greice Krautz-Peterson, Cibele A Tararam, Bogar O Araujo-Montoya, Tatiana R Fraga, Henrique K Rofatto, Floriano P Silva, Lourdes Isaac, Akram A Da'dara, R Alan Wilson, Charles B Shoemaker, Luciana C C Leite
Published 2013-01-01

Camelid VHH Antibodies that Neutralize Botulinum Neurotoxin Serotype E Intoxication or Protease Function

by Jacqueline M. Tremblay, Edwin Vazquez-Cintron, Kwok-Ho Lam, Jean Mukherjee, Daniela Bedenice, Celinia A. Ondeck, Matthieu T. Conroy, Skylar M. L. Bodt, Brittany M. Winner, Robert P. Webb, Konstantin Ichtchenko, Rongsheng Jin, Patrick M. McNutt, Charles B. Shoemaker
Published 2020-09-01