Metabolomics and cardiovascular imaging: a combined approach for cardiovascular ageing

by Angela S. Koh, Jean‐Paul Kovalik
Published 2021-06-01

The acute transcriptional responses to dietary methionine restriction are triggered by inhibition of ternary complex formation and linked to Erk1/2, mTOR, and ATF4

by Kirsten P. Stone, Sujoy Ghosh, Jean Paul Kovalik, Manda Orgeron, Desiree Wanders, Landon C. Sims, Thomas W. Gettys
Published 2021-02-01

Diabetic Endothelial Cells Differentiated From Patient iPSCs Show Dysregulated Glycine Homeostasis and Senescence Associated Phenotypes

by Liping Su, Xiaocen Kong, Sze Jie Loo, Yu Gao, Jean-Paul Kovalik, Xiaofei Su, Jianhua Ma, Lei Ye
Published 2021-05-01

Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation

by Kyung Cheul Shin, Injae Hwang, Sung Sik Choe, Jeu Park, Yul Ji, Jong In Kim, Gha Young Lee, Sung Hee Choi, Jianhong Ching, Jean-Paul Kovalik, Jae Bum Kim
Published 2017-10-01

Effects of laparoscopic sleeve gastrectomy on concentration and composition of bile acids in an Asian population with morbid obesity

by Jie Yao, Jean-Paul Kovalik, Oi Fah Lai, Phong Ching Lee, Alvin Kim Hock Eng, Weng Hoong Chan, Eugene Kee Wee Lim, Yong Mong Bee, Hong Chang Tan
Published 2021-06-01

Profiling of Plasma Metabolites Suggests Altered Mitochondrial Fuel Usage and Remodeling of Sphingolipid Metabolism in Individuals With Type 2 Diabetes and Kidney Disease

by Jian-Jun Liu, Sujoy Ghosh, Jean-Paul Kovalik, Jianhong Ching, Hyung Won Choi, Subramaniam Tavintharan, Choon Nam Ong, Chee Fang Sum, Scott A. Summers, E. Shyong Tai, Su Chi Lim
Published 2017-05-01

Prdm16 Deficiency Leads to Age-Dependent Cardiac Hypertrophy, Adverse Remodeling, Mitochondrial Dysfunction, and Heart Failure

by Dasan Mary Cibi, Kathleen Wung Bi-Lin, Shamini Guna Shekeran, Reddemma Sandireddy, Nicole Tee, Anamika Singh, Yajun Wu, Dinesh Kumar Srinivasan, Jean-Paul Kovalik, Sujoy Ghosh, Patrick Seale, Manvendra K. Singh
Published 2020-10-01

Metabolic stress is a primary pathogenic event in transgenic Caenorhabditis elegans expressing pan-neuronal human amyloid beta

by Emelyne Teo, Sudharshan Ravi, Diogo Barardo, Hyung-Seok Kim, Sheng Fong, Amaury Cazenave-Gassiot, Tsze Yin Tan, Jianhong Ching, Jean-Paul Kovalik, Markus R Wenk, Rudiyanto Gunawan, Philip K Moore, Barry Halliwell, Nicholas Tolwinski, Jan Gruber
Published 2019-10-01

Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction

by Leonardo P. de Carvalho, MD, PhD, Sock Hwee Tan, PhD, Ghim-Siong Ow, BSc, Zhiqun Tang, PhD, Jianhong Ching, PhD, Jean-Paul Kovalik, MD, PhD, Sock Cheng Poh, BSc, Chee-Tang Chin, MBBS, A. Mark Richards, MD, PhD, Eliana C. Martinez, MD, PhD, Richard W. Troughton, MD, PhD, Alan Yean-Yip Fong, MBBS, Bryan P. Yan, MBBS, Aruni Seneviratna, MBBS, MPH, Vitaly Sorokin, MD, PhD, Scott A. Summers, PhD, Vladimir A. Kuznetsov, PhD, SciD, Mark Y. Chan, MBBS, PhD
Published 2018-04-01