Electrospun Microfibers Modulate Intracellular Amino Acids in Liver Cells via Integrin β1

by Tianjiao Huang, John A. Terrell, Jay H. Chung, Chengpeng Chen
Published 2021-06-01

CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage.

by Hyeog Kang, Jae-Won Jung, Myung K Kim, Jay H Chung
Published 2009-08-01

AMPK regulates circadian rhythms in a tissue- and isoform-specific manner.

by Jee-Hyun Um, Julie S Pendergast, Danielle A Springer, Marc Foretz, Benoit Viollet, Alexandra Brown, Myung K Kim, Shin Yamazaki, Jay H Chung
Published 2011-03-01

Potent PDE4 inhibitor activates AMPK and Sirt1 to induce mitochondrial biogenesis.

by Sung-Jun Park, Faiyaz Ahmad, Robert J Bahde, Andrew Philp, Jeonghan Kim, Tianjiao Huang, Myung K Kim, William C Trenkle, Jay H Chung
Published 2021-01-01

The Multifunctional Sorting Protein PACS-2 Regulates SIRT1-Mediated Deacetylation of p53 to Modulate p21-Dependent Cell-Cycle Arrest

by Katelyn M. Atkins, Laura L. Thomas, Jonathan Barroso-González, Laurel Thomas, Sylvain Auclair, Jun Yin, Hyeog Kang, Jay H. Chung, Jimmy D. Dikeakos, Gary Thomas
Published 2014-09-01

Specific Sirt1 Activator-mediated Improvement in Glucose Homeostasis Requires Sirt1-Independent Activation of AMPK

by Sung-Jun Park, Faiyaz Ahmad, Jee-Hyun Um, Alexandra L. Brown, Xihui Xu, Hyeog Kang, Hengming Ke, Xuesong Feng, James Ryall, Andrew Philp, Simon Schenk, Myung K. Kim, Vittorio Sartorelli, Jay H. Chung
Published 2017-04-01

Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins

by Hyeog Kang, Shinichi Oka, Duck-Yeon Lee, Junhong Park, Angel M. Aponte, Young-Sang Jung, Jacob Bitterman, Peiyong Zhai, Yi He, Hamed Kooshapur, Rodolfo Ghirlando, Nico Tjandra, Sean B. Lee, Myung K. Kim, Junichi Sadoshima, Jay H. Chung
Published 2017-05-01