Mycophenolic acid and 6-mercaptopurine both inhibit B-cell proliferation in granulomatosis with polyangiitis patients, whereas only mycophenolic acid inhibits B-cell IL-6 productio...

by Anouk von Borstel, Wayel H Abdulahad, Gerjan Dekkema, Abraham Rutgers, Coen A Stegeman, Johanna Veldman, Peter Heeringa, Jan Stephan Sanders
Published 2020-01-01

M2 macrophage is the predominant phenotype in airways inflammatory lesions in patients with granulomatosis with polyangiitis

by Alexandre Wagner Silva de Souza, Mirjan van Timmeren, Jan-Stephan Sanders, Coen Stegeman, Peter Heeringa, Cees G. M. Kallenberg, Johanna Westra
Published 2017-05-01

CD27+CD38hi B Cell Frequency During Remission Predicts Relapsing Disease in Granulomatosis With Polyangiitis Patients

by Anouk von Borstel, Judith Land, Wayel H. Abdulahad, Wayel H. Abdulahad, Abraham Rutgers, Coen A. Stegeman, Arjan Diepstra, Peter Heeringa, Jan Stephan Sanders
Published 2019-09-01

A delicate balance between rejection and BK polyomavirus associated nephropathy; A retrospective cohort study in renal transplant recipients.

by Lilli Gard, Willem van Doesum, Hubert G M Niesters, Willem J van Son, Arjan Diepstra, Coen A Stegeman, Henk Groen, Annelies Riezebos-Brilman, Jan Stephan Sanders
Published 2017-01-01

Increased miR-142-3p Expression Might Explain Reduced Regulatory T Cell Function in Granulomatosis With Polyangiitis

by Gerjan J. Dekkema, Theo Bijma, Theo Bijma, Pytrick G. Jellema, Anke Van Den Berg, Bart-Jan Kroesen, Coen A. Stegeman, Peter Heeringa, Wayel H. Abdulahad, Wayel H. Abdulahad, Jan-Stephan Sanders
Published 2019-09-01

Urinary Properdin and sC5b-9 Are Independently Associated With Increased Risk for Graft Failure in Renal Transplant Recipients

by Rosa G. M. Lammerts, Michele F. Eisenga, Mohammed Alyami, Mohamed R. Daha, Marc A. Seelen, Robert A. Pol, Jacob van den Born, Jan-Stephan Sanders, Stephan J. L. Bakker, Stefan P. Berger
Published 2019-10-01

Biopsy-Controlled Non-Invasive Quantification of Collagen Type VI in Kidney Transplant Recipients: A Post-Hoc Analysis of the MECANO Trial

by Manuela Yepes-Calderón, Camilo G. Sotomayor, Daniel Guldager Kring Rasmussen, Ryanne S. Hijmans, Charlotte A. te Velde-Keyzer, Marco van Londen, Marja van Dijk, Arjan Diepstra, Stefan P. Berger, Morten Asser Karsdal, Frederike J. Bemelman, Johan W. de Fijter, Jesper Kers, Sandrine Florquin, Federica Genovese, Stephan J. L. Bakker, Jan-Stephan Sanders, Jacob Van Den Born
Published 2020-10-01

PIRCHE-II Is Related to Graft Failure after Kidney Transplantation

by Kirsten Geneugelijk, Matthias Niemann, Julia Drylewicz, Arjan D. van Zuilen, Irma Joosten, Wil A. Allebes, Arnold van der Meer, Luuk B. Hilbrands, Marije C. Baas, C. Erik Hack, Franka E. van Reekum, Marianne C. Verhaar, Elena G. Kamburova, Michiel L. Bots, Marc A. J. Seelen, Jan Stephan Sanders, Bouke G. Hepkema, Annechien J. Lambeck, Laura B. Bungener, Caroline Roozendaal, Marcel G. J. Tilanus, Joris Vanderlocht, Christien E. Voorter, Lotte Wieten, Elly M. van Duijnhoven, Mariëlle Gelens, Maarten H. L. Christiaans, Frans J. van Ittersum, Azam Nurmohamed, Junior N. M. Lardy, Wendy Swelsen, Karlijn A. van der Pant, Neelke C. van der Weerd, Ineke J. M. ten Berge, Fréderike J. Bemelman, Andries Hoitsma, Paul J. M. van der Boog, Johan W. de Fijter, Michiel G. H. Betjes, Michiel G. H. Betjes, Sebastiaan Heidt, Dave L. Roelen, Frans H. Claas, Henny G. Otten, Eric Spierings
Published 2018-03-01

Development and Validation of a Multiplex Non-HLA Antibody Assay for the Screening of Kidney Transplant Recipients

by Elena G. Kamburova, Tineke Kardol-Hoefnagel, Bram W. Wisse, Irma Joosten, Wil A. Allebes, Arnold van der Meer, Luuk B. Hilbrands, Marije C. Baas, Eric Spierings, Cornelis E. Hack, Franka E. van Reekum, Arjan D. van Zuilen, Marianne C. Verhaar, Michiel L. Bots, Adriaan C. A. D. Drop, Loes Plaisier, Jan Meeldijk, Niels Bovenschen, Niels Bovenschen, Marc A. J. Seelen, Jan Stephan Sanders, Bouke G. Hepkema, Annechien J. A. Lambeck, Laura B. Bungener, Caroline Roozendaal, Marcel G. J. Tilanus, Christina E. Voorter, Lotte Wieten, Elly M. van Duijnhoven, Mariëlle A. C. J. Gelens, Maarten H. L. Christiaans, Frans J. van Ittersum, Shaikh A. Nurmohamed, Neubury M. Lardy, Wendy Swelsen, Karlijn A. M. I. van der Pant, Neelke C. van der Weerd, Ineke J. M. ten Berge, Frederike J. Bemelman, Paul J. M. van der Boog, Johan W. de Fijter, Michiel G. H. Betjes, Sebastiaan Heidt, Dave L. Roelen, Frans H. Claas, Henny G. Otten
Published 2018-12-01