Targeting tubulointerstitial remodeling in proteinuric nephropathy in rats

by Saleh Yazdani, Ryanne S. Hijmans, Fariba Poosti, Wendy Dam, Gerjan Navis, Harry van Goor, Jacob van den Born
Published 2015-08-01

Dapagliflozin Attenuates Renal Tubulointerstitial Fibrosis Associated With Type 1 Diabetes by Regulating STAT1/TGFβ1 Signaling

by Fengjuan Huang, Fengjuan Huang, Yanyan Zhao, Qingzhu Wang, Jan-Luuk Hillebrands, Jacob van den Born, Linlin Ji, Tingting An, Guijun Qin
Published 2019-07-01

Differential Effects of Long Term FTY720 Treatment on Endothelial versus Smooth Muscle Cell Signaling to S1P in Rat Mesenteric Arteries.

by Mahdi Hamidi Shishavan, Arash Bidadkosh, Saleh Yazdani, Sebastiaan Lambooy, Jacob van den Born, Hendrik Buikema, Robert H Henning, Leo E Deelman
Published 2016-01-01

Differential expression of proteoglycans in tissue remodeling and lymphangiogenesis after experimental renal transplantation in rats.

by Heleen Rienstra, Kirankumar Katta, Johanna W A M Celie, Harry van Goor, Gerjan Navis, Jacob van den Born, Jan-Luuk Hillebrands
Published 2010-01-01

Properdin Pattern Recognition on Proximal Tubular Cells Is Heparan Sulfate/Syndecan-1 but Not C3b Dependent and Can Be Blocked by Tick Protein Salp20

by Rosa G. M. Lammerts, Ditmer T. Talsma, Wendy A. Dam, Mohamed R. Daha, Marc A. J. Seelen, Stefan P. Berger, Jacob van den Born
Published 2020-08-01

Serum Carnosinase-1 and Albuminuria Rather than the CNDP1 Genotype Correlate with Urinary Carnosinase-1 in Diabetic and Nondiabetic Patients with Chronic Kidney Disease

by Angelica Rodriguez-Niño, Sibylle J. Hauske, Anna Herold, Jiedong Qiu, Jacob van den Born, Stephan J. L. Bakker, Bernhard K. Krämer, Benito A. Yard
Published 2019-01-01

Basement membrane zone collagens XV and XVIII/proteoglycans mediate leukocyte influx in renal ischemia/reperfusion.

by Azadeh Zaferani, Ditmer T Talsma, Saleh Yazdani, Johanna W A M Celie, Mari Aikio, Ritva Heljasvaara, Gerjan J Navis, Taina Pihlajaniemi, Jacob van den Born
Published 2014-01-01

Incomplete Restoration of Angiotensin II-Induced Renal Extracellular Matrix Deposition and Inflammation Despite Complete Functional Recovery in Rats.

by Anne-Roos S Frenay, Saleh Yazdani, Miriam Boersema, Anne Marijn van der Graaf, Femke Waanders, Jacob van den Born, Gerjan J Navis, Harry van Goor
Published 2015-01-01

Methylglyoxal induces p53 activation and inhibits mTORC1 in human umbilical vein endothelial cells

by Xinmiao Zhang, Angelica Rodriguez-Niño, Diego O. Pastene, Prama Pallavi, Jacob van den Born, Stephan J. L. Bakker, Bernhard K. Krämer, Benito A. Yard
Published 2021-04-01

Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases

by Marloes Sol, Jan A. A. M. Kamps, Jacob van den Born, Marius C. van den Heuvel, Johan van der Vlag, Guido Krenning, Jan-Luuk Hillebrands
Published 2020-10-01

High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats.

by Ryanne S Hijmans, Pragyi Shrestha, Kwaku A Sarpong, Saleh Yazdani, Rana El Masri, Wilhelmina H A de Jong, Gerjan Navis, Romain R Vivès, Jacob van den Born
Published 2017-01-01

Increased migration of antigen presenting cells to newly-formed lymphatic vessels in transplanted kidneys by glycol-split heparin.

by Ditmer T Talsma, Kirankumar Katta, Miriam Boersema, Saritha Adepu, Annamaria Naggi, Giangiacomo Torri, Coen Stegeman, Gerjan Navis, Harry van Goor, Jan-Luuk Hillebrands, Saleh Yazdani, Jacob van den Born
Published 2017-01-01

Direct Evidence of Endothelial Dysfunction and Glycocalyx Loss in Dermal Biopsies of Patients With Chronic Kidney Disease and Their Association With Markers of Volume Overload

by Josephine Koch, Ryanne S. Hijmans, Manuela Ossa Builes, Wendy A. Dam, Robert A. Pol, Stephan J. L. Bakker, Hendri H. Pas, Casper F. M. Franssen, Jacob van den Born
Published 2021-09-01

Association of plasma somatostatin with disease severity and progression in patients with autosomal dominant polycystic kidney disease

by A. Lianne Messchendorp, Edwin M. Spithoven, Niek F. Casteleijn, Wendy A. Dam, Jacob van den Born, Wouter F. Tonnis, Carlo A. J. M. Gaillard, Esther Meijer, on behalf of the DIPAK Consortium
Published 2018-12-01

Dermal tissue remodeling and non-osmotic sodium storage in kidney patients

by Ryanne S. Hijmans, Marco van Londen, Kwaku A. Sarpong, Stephan J. L. Bakker, Gerjan J. Navis, Twan T. R. Storteboom, Wilhelmina H. A. de Jong, Robert A. Pol, Jacob van den Born
Published 2019-03-01

An observational study on intracutaneous sodium storage in intensive care patients and controls.

by Marjolein van IJzendoorn, Jacob van den Born, Ryanne Hijmans, Rianne Bodde, Hanneke Buter, Wendy Dam, Peter Kingma, Gwendolyn Maes, Tsjitske van der Veen, Wierd Zijlstra, Baukje Dijkstra, Gerjan Navis, Christiaan Boerma
Published 2019-01-01

Urinary Properdin and sC5b-9 Are Independently Associated With Increased Risk for Graft Failure in Renal Transplant Recipients

by Rosa G. M. Lammerts, Michele F. Eisenga, Mohammed Alyami, Mohamed R. Daha, Marc A. Seelen, Robert A. Pol, Jacob van den Born, Jan-Stephan Sanders, Stephan J. L. Bakker, Stefan P. Berger
Published 2019-10-01

Proteinuria triggers renal lymphangiogenesis prior to the development of interstitial fibrosis.

by Saleh Yazdani, Fariba Poosti, Andrea B Kramer, Katarina Mirković, Arjan J Kwakernaak, Menno Hovingh, Maartje C J Slagman, Klaas A Sjollema, Martin H de Borst, Gerjan Navis, Harry van Goor, Jacob van den Born
Published 2012-01-01

Urinary vitamin D binding protein: a potential novel marker of renal interstitial inflammation and fibrosis.

by Katarina Mirković, Carolina R C Doorenbos, Wendy A Dam, Hiddo J Lambers Heerspink, Maartje C J Slagman, Ferdau L Nauta, Andrea B Kramer, Ronald T Gansevoort, Jacob van den Born, Gerjan Navis, Martin H de Borst
Published 2013-01-01

The CNDP1 (CTG)5 Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration

by Thomas Albrecht, Shiqi Zhang, Jana D. Braun, Li Xia, Angelica Rodriquez, Jiedong Qiu, Verena Peters, Claus P. Schmitt, Jacob van den Born, Stephan J. L. Bakker, Alexander Lammert, Hannes Köppel, Peter Schnuelle, Bernhard K. Krämer, Benito A. Yard, Sibylle J. Hauske
Published 2017-01-01